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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene.  In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma.  More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.

LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

CHENGDU, Sept. 20 (Xinhua) -- A United Nations official said Tuesday that she hopes China will take every opportunity to reinforce, support and lead the UN's agenda and "infuse it with strength and wisdom.""The more China gives, the better the UN can become," said Renata Lok-Dessallien, UN Resident Coordinator and United Nations Development Program (UNDP) Resident Representative in China, at the Seminar in Memory of the 40th Anniversary of the Resumption of Lawful Rights of China in the United Nations.The three-day seminar from Sept. 19 to 21 is being held in the city of Chengdu in southwest China's Sichuan Province. About 100 UN and Chinese officials are gathering to discuss China's role in the UN, as well as the UN's role in global diplomacy.Lok-Dessallien said that the General Assembly Resolution of Oct. 25, 1971 was an "important milestone in China's international relations and in the history of the United Nations.""It restored the rights of the People's Republic of China in the United Nations and marked China's entry to the world stage," she said.Steven Sabey, a senior policy advisor from the UNDP's China office, said that China plays an important role in facilitating cooperation about the member states of the United Nations."China needs the United Nations, and the United Nations also needs China," said Wu Hailong, China's assistant minister of foreign affairs."We must recognize that as the largest developing country in the world, China needs to manage its domestic affairs first, as this can have a positive effect on humanity as a whole," Wu said.As China's role in the world continues to grow and evolve, the UN's role in China will also grow, according to Lok-Dessallien."As China's development trajectory continues to evolve, we are entering significantly new territory in the UN-China relationship," she said.Sabey said that he hopes China will strengthen its cooperation with the United Nations in order to further improve intercultural communication and allow China to contribute more to other developing countries."The United Nations is committed to continuing to deepen and strengthen our partnership as we tackle the many global challenges ahead," said Lok-Dessallien.

PARIS, Aug. 7 (Xinhua) -- European heavy-lift launcher Ariane 5 lifted off two communication satellites on Saturday.The Ariane 5, carrying Astra 1N and BSAT-3c/JCSAT-110R, was launched at 2252 GMT on Saturday from Kourou launch centre in French Guiana, according to live broadcast of the launching process.This was the fourth mission of Ariane 5 in 2011 and its 203th flight that sent off the two satellites Saturday night to their respective geostationary transfer orbits.Astra 1N, to be separated first, is built by EADS Astrium in Toulouse, France, for the Luxembourg-based operator SES Astra. With a designed lifespan of 15 years, it has an estimated liftoff mass of 5,350 kg and is fitted with 52 active Ku-band transponders.It is initially to deliver interim capacity from an orbital position of 28.2 degree East, and will subsequently move to SES Astra's prime location at 19.2 degree East for primary and backup services.BSAT-3c/JCSAT-110R is manufactured by Lockheed Martin Commercial Space Systems in Newtown, Pennsylvania, for Japanese operators B-SAT Corporation and SKY Perfect JSAT Corporation. This satellite weighs approximately 2,910 kg at launch time. It is to be positioned at 110 degree East longitude in geostationary orbit with a lifetime exceeding 16 years.This Ariane 5 flight has been postponed twice, firstly due to some technical problem in early July and then delayed by bad weather.Arianespace plans to achieve six Ariane 5 missions through this year.

SUVA, Sept. 21 (Xinhua) -- The Secretariat of the Pacific Community (SPC) stressed on Wednesday that sustainable use and management of forests and tree resources will remain its important focus for the foreseeable future.Sairusi Bulai, a forestry team coordinator of SPC's Land Resources Division (LRD) told a regional workshop currently underway in Fiji's western tourist city of Nadi that "our main issue was and continues to be the lack of adequate resources to enable countries to effectively implement sustainable forest management.""Therefore, we are very fortunate that we have this opportunity to discuss findings and recommendations of the mission, which the UN-REDD Program has undertaken in the Pacific earlier this year," he added.REDD+ is a new international mechanism to compensate developing countries for reducing their rate of deforestation and forest degradation and increasing their carbon stocks.Developing countries participate on a voluntary basis. They provide technical and financial assistance to enable eligible countries to meet the requirements for future participation. Once a country begins participating, it receives compensation for its verified reduction in carbon emission from forest activities.The UN-REDD Program is a collaborative partnership of the United Nations Development Program (UNDP), the United Nations Environment Program (UNEP) and the Food and Agriculture Organization (FAO) to support countries in the preparation of this mechanism.Bulai encouraged participants to take advantage of the excellent opportunity to discuss REDD+ experiences in the region and to link up with the experts in attendance.REDD+ gives an excellent opportunity to create better awareness and understanding amongst all stakeholders, including resource owners, so that informed decisions are made to avoid exploitation, he said.Bulai, meanwhile, stressed on the critical importance of multi- sectoral as well as multi-stakeholder based approaches to forest management to effectively reduce deforestation and forest degradation.