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(KGTV) -- Many scientists and doctors are cautiously optimistic about taking a step forward in the fight against COVID-19 after encouraging news from Pfizer Monday.Pfizer announced that early data revealed its vaccine was more than 90 percent effective in protecting trial participants against the coronavirus.The U.S. Federal Food and Drug Admiration still needs to review the drug for safety and efficacy, and Pfizer plans to seek an Emergency Use Authorization this month, but regardless some see this as a good sign for other vaccine trials.“I think this is frankly the break we’ve all been waiting for, and I hope we have many others to follow,” said Dr. Susan Little, a UC San Diego Professor of Medicine.UCSD is participating in Phase 3 clinical trials for Moderna, AstraZeneca, and Janssen vaccines.Little leads the AstraZeneca and Janssen trials, which resumed locally last week.“I think what this means for all of the trials that are available at this stage, this is incredibly good news,” she said. “So far, they all use the same approach to vaccine development; they are all targeting the same protein, the spike protein, on the coronavirus.”She expects similar results to come from Moderna’s early data sometime this year.“The Pfizer and the Moderna both use the same vaccine platform, the same structure for their vaccine construct, so there’s every reason to be very optimistic the Moderna study might show similar results,” she said. “While the AstraZeneca and the Janssen use a different vaccine construct, they both are targeting the same protein.”If Pfizer’s vaccine is approved, it could be given to healthcare workers and high-risk populations in just months, and the general population in 2021, according to Pfizer.Pfizer said it expects to produce 50 million vaccine doses globally in 2020 and up to 1.3 billion in 2021.Pfizer’s CEO, Albert Bourla, said he expects the vaccine to be free of charge for Americans. 1943

(KGTV/WXYZ) - Less than two months after a report said Toys 'R' Us would close many of its U.S. stores, a new report said the toy store is considering closing all stores. 178

(KGTV) - The National Football League said Tuesday it does not support a GOP-backed tax bill that could force teams to put up more of their own funds for any stadium construction, according to Reuters.The bill, introduced in the U.S. House of Representatives last week, would prevent local governments from funding the building or renovating of professional sports stadiums with tax-exempt, public-purpose bonds - commonly used to fund projects related to schools, libraries, and public transit.RELATED: GOP leaders unveil key details in new tax planAccording to NFL spokesman Joe Lockhart, the league believes the economic development from stadiums should make those projects eligible for tax breaks. 729

(KGTV) - The mass shooting at an El Paso, Texas, Walmart Saturday had the city scrambling to rush the victims to hospitals and lock down nearby businesses for safety.While the crime scene remained focused on the store off Interstate 10, the area affected by the emergency spread across the border town of roughly 685,000.See the interactive map: 353

6/10"Paper Mario: The Origami King" tries really hard to make a good first impression. The game’s art style is dressed up to dazzle, the gameplay is simple and approachable, and the music is among the best of any Switch game to date. With every preceding moment, however, this game’s chores began to outweigh its charm, making it a paper-thin adventure for Nintendo’s most iconic character and one of the more disappointing gaming experiences of 2020.The Paper Mario series is known for its turn-based combat, and this entry continues that tradition. Even though it introduces a new ring-based battlefield that requires enemies to be lined up prior to the attack, it maintains the typical exchange of blows until HP is depleted. Rotating enemies is extremely repetitive, but it’s a lack of a leveling-up system that truly makes the combat feel like a drag. The absence of a skill tree equivalent not only creates for less attention to detail in battles, but it also had me wanting to avoid them altogether. Rather than gaining experience points, you’re rewarded with coins that allow for purchasing weapons (that eventually break down) and extra health, but with the game’s battles being so easy, I rarely felt the need to purchase anything. Boss battles provide a slightly tougher challenge, but after a few failed runs, even they begin to feel like busywork, making me long for a meaty JRPG experience with a purpose. 1427