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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Singer R. Kelly appeared in a Chicago court Wednesday, where a judge said he would like to set a trial date for early next year and prosecutors turned over a DVD allegedly showing pornographic images involving a minor.Kelly pleaded not guilty earlier this month to 11 new charges in his sexual assault and sexual abuse case, according to his attorney, Steve Greenberg.During the brief hearing Wednesday, state prosecutors turned over DVDs allegedly containing pornographic evidence involving a minor."We'll see what it shows, we'll make our assessment on it," Greenberg told reporters after the hearing.Kelly, wearing a dark suit and flanked by his legal team, did not address the court or the media after the hearing.Judge Lawrence Flood placed a protective order on the DVDs and warned both parties against leaking them."If there's any violation of this protective order, I'm going to impose sanctions, severe sanctions," he said. "I just want everybody on notice with that. Plus, there could be criminal implications to violation of this protective order."Kelly remains free on bonds totaling million that were set in February. The next hearing in his case is scheduled for August 15.After the hearing, Kelly's spokesman Darrell Johnson said the singer looked forward to the start of the trial."I think that's great ... The faster the better," Johnson said of an early 2020 trial, adding that Kelly is "living on royalties right now."Greenberg, outside court, enumerated what he said were a number of problems with the case, including improperly collected and tested scientific evidence and issues with the statute of limitations.Kelly initially was charged in February with 10 counts of aggravated criminal sexual abuse -- a Class 2 felony -- involving four alleged victims, including three who prosecutors say were underage girls. The charges, to which he pleaded not guilty, cover allegations from 1998 to 2010.In late May, a grand jury indicted him with 11 more charges pertaining to one of those four accusers. Those charges included not only aggravated criminal sexual abuse but also more serious charges: aggravated criminal sexual assault, a Class X felony; and criminal sexual assault, a Class 1 felony.A person convicted of Class X felonies generally can be sentenced to up to 30 years in prison, according to Illinois law. Class 1 and 2 felonies generally carry lower maximum penalties.Kelly, 52, has vehemently denied any allegations of sexual misconduct.The singer also was released on bail in March in a case in which authorities have said he failed to pay his ex-wife child support of 1,000.Kelly has faced accusations of abuse, manipulation and inappropriate encounters with girls and young women for more than two decades.In a March interview with CBS, he said: "I'm very tired of all of the lies. I've been hearing things and seeing things on all of the blogs and I'm just tired." 2919

Sad to report that the number of fatalities increased by one. Victim passed early this morning at the hospital.— EL PASO POLICE DEPT (@EPPOLICE) August 5, 2019 172

Rep. Seth Moulton will end his presidential bid on Friday during a speech at the Democratic National Committee summer meeting in San Francisco, according to prepared remarks of the speech the Massachusetts Democrat plans to deliver.The decision closes out a campaign in which the candidate failed to get traction or make this year's Democratic debates."Today, I want to use this opportunity, with all of you here, to announce that I am ending my campaign for president," Moulton plans to tell the DNC meeting. "Though this campaign is not ending the way we hoped, I am leaving this race knowing that we raised issues that are vitally important to the American people and our future."Moulton, a Marine veteran and three-term congressman who represents Boston's northern suburbs, will tell the audience that he plans to run for reelection to Congress and relaunch Serve America, a PAC that looks to elect Democrats with service backgrounds."I will continue to fight for a new generation of leadership in our party and our country," he plans to say. "And most of all, I will be campaigning my ass off for whoever wins our nomination in 2020."Moulton entered the race later than most -- in late April -- and failed to catch on with more than 20 Democrats vying to take on President Donald Trump.The congressman failed to register in national or statewide polls and did not garner the needed fundraising to qualify for either the June or July Democratic debates.Moulton centered his bid on his personal military service and traveled the country to talk about his plan to incentivize national service at events during which the congressman personally did a service project. Moulton had hoped that his focus on national security and service would set him apart in the large Democratic field, but the congressman was boxed out by other military veterans -- namely Hawaii Rep. Tulsi Gabbard and South Bend, Indiana, Mayor Pete Buttigieg.Moulton has told staff and friends that he plans to continue pushing the Democratic Party on issues that motivated his campaign, like issues facing veterans, the need to incentivize national service and the importance of a comprehensive strategy around national defense.Those efforts will commence on Monday when Moulton hosts a town hall for veterans in Fairfax, Virginia, alongside General Stanley McChrystal, a military leader who endorsed Moulton's 2020 bid.Aides to the congressman said they hope that he could be in line for a host of administration posts, should a Democrat in the White House in 2020, including secretary of veterans affairs, defense secretary and United Nations ambassador.Moulton is the latest Democratic candidate to get out of the 2020 race, following California Rep. Eric Swalwell, former Colorado Gov. John Hickenlooper and Washington Gov. Jay Inslee. 2821

TAMPA, Florida — Many people see living in Florida as the dream, which may be why 149 people move to Tampa every day, according to a Bloomberg report. 162