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SAN FRANCISCO, June 13 (Xinhua) -- Social networking giant Facebook will likely go public in the first quarter of 2012 with a valuation that could top 100 billion U.S. dollars, U.S. media reported on Monday.In a report, CNBC quoted people familiar with the matter as saying that Facebook could submit filing to register its securities with the U.S. Securities and Exchange Commission (SEC) as early as October or November this year.People who are on Wall Street and track this information told the business news television channel that they think the Facebook initial public offering (IPO), if and when it happens could value the company of more than 100 billion dollars.A factor in the company's IPO timing is the SEC's requirement that companies must disclose financial information if they have more than 500 private investors."The company has until the end of April 2012 to disclose their financials, but they may just want to get ahead of that by doing a formal initial public offering, I'm told. And that could happen in the first quarter of the year," said CNBC Wall Street reporter Kate Kelly.Facebook is also facing internal pressure as employees have not been permitted to sell their private shares on the secondary market since last spring. An IPO would make it easier for employees to monetize their shares, said Kelly, citing sources.Facebook shares have been traded in private markets such as Sharepost.com, which puts the social networking company's valuation at 85 billion dollars.Meanwhile, latest data show that Facebook is losing users last month in the United States, Canada and several European countries, indicating that the company could have hit the limits of expansion in its mature markets.

SAN FRANCISCO, June 13 (Xinhua) -- Google on Monday confirmed that it had signed an agreement to buy Admeld, an on-line advertising optimization firm, in a deal seen as the Internet search giant's latest move to bolster its on-line display ad business.Admeld, launched in 2007 and headquartered in New York City, has developed a service that can help on-line publishers manage their ad space more efficiently and profitably.Admeld now has more than 500 customers worldwide, among them are FOX News, IDG TechNetwork, Discovery and The Weather Channel, according to information posted on its website."By combining Admeld's services, expertise and technology with Google's offerings, we're investing in what we hope will be an improved era of flexible ad management tools for major publishers, " Neal Mohan, Google's vice president of display advertising, said in a blog post announcing the deal."We believe that this investment will be an important step to help on-line publishers, and will further improve and grow the display advertising industry as a whole," Mohan noted.On-line display ads usually appear in forms that consist of images and may be interactive. According to the Interactive Advertising Bureau, a U.S. trade association, display-related on- line ad revenue in the United States totaled nearly 10 billion U.S. dollars in 2010.Financial terms of the deal were not disclosed by the two companies. TechCrunch, a technology blog site, has reported that Google paid around 400 million dollars.

COPENHAGEN, June 7 (Xinhua) -- The outbreak of infections caused by E. coli bacteria may be over in Denmark as no new cases have been reported here since Friday.According to Denmark's National Serum Institute (NSI), there are 18 confirmed cases of severe intestinal infection caused by exposure to the bacteria as of Monday. No new infections have been reported since Friday, it added.The confirmed cases are said to consist of 10 men and 8 women aged between 23 and 81 years of age. Seven show symptoms of kidney failure which is associated with advanced stages of the infection.All but one are believed to have contracted the infection while traveling in northern Germany, where the outbreak started, the NSI said.So far, the E. coli infection has claimed 21 lives in Germany, which reports over 2,100 confirmed and suspected cases. It has also spread to 12 countries according to the World Health Organization (WHO)."This particular strain of E.coli has been identified in some people sporadically in the past, but it has not been known to have been associated with outbreaks in the past," a WHO spokesperson said Friday, adding it was a "very, very rare strain."Health authorities in Germany now suspect bean sprouts as the source of contamination in this outbreak, although this is yet to be confirmed.Dr Kaare Moelbak, an epidemiologist at NSI told Danish media Sunday that bean sprouts were a "very likely" source of contamination.Cucumbers were initially suspected and Denmark's food authority continues to warn against eating raw tomato, cucumber or lettuce from Germany until the source is established.Children are normally most vulnerable to E. coli infection but most of those infected in this outbreak are above the age of 20 years, Moelbak told Xinhua last week.He said children are likely less affected by this outbreak as they usually eat fewer salads than adults.In Germany, it is mostly women who have been affected by the infection. Moelbak explained the skew in infections saying women tend to choose to eat more vegetables than men, in comments made to Danish media Thursday.

SAN FRANCISCO, July 20 (Xinhua) -- Google announced on Wednesday that it has reached a deal with author J.K. Rowling to launch the series of Harry Potter ebooks on Google's platform.When the series of Harry Potter ebooks launch on Pottermore.com in early October, the bestsellers will be available in the United States via Google eBooks platform, said Google in a blog post.When customers buy a Harry Potter ebook from Pottermore.com, they will be able to choose to keep it in their Google's online library in the cloud, as well as other e-reading platforms.Google said Google eBooks can be read on most devices with a modern browser, through Google apps for iOS and Android smartphones and tablets, and on more than 80 e-readers.Meanwhile, Rowling will continue to issue announcements via YouTube, as she announced Pottermore.com in June.The two sides also agreed to make Google Checkout the preferred third-party payment platform for all purchases made on Rowling's Pottermore.com.Pottermore.com, which will be launched on July 31, will sell ebook and audiobook versions of the seven Harry Potter novels, as well as additional content including background details and settings.According to The Times, the Harry Potter brand value is estimated to be more than 15 billion U.S. dollars. The deal could make Google move some e-reader customers from competitors like Amazon, whose e-reader Kindle does not support Google eBooks.

WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.