喀什怎么提高男性性能力(喀什男性勃起功能障碍怎么办) (今日更新中)

WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

SAN FRANCISCO, April 27 (Xinhua) -- Apple Inc. on Wednesday denied the alleged location-tracking practice of its mobile operating system, saying it will release software updates to make iPhone store less location information to quell public concerns over privacy.CLARIFICATION"Apple is not tracking the location of your iPhone. Apple has never done so and has no plans to ever do so," the company said in a statement."Users are confused, partly because the creators of this new technology (including Apple) have not provided enough education about these issues to date."According to the statement, the location data researchers saw on iPhone is a database of Wi-Fi hotspots and cell towers around users' current location that Apple is maintaining to help iPhone rapidly and accurately calculate its location when requested. It noted Apple cannot locate iPhone users based on Wi-Fi hotspot and cell tower data as the information is in an anonymous and encrypted form.Apple admitted that part of the location data (Wi-Fi hotspots and cell towers) is backed up on iTunes, which means it could be possible that people with access to iPhone users'computer may get their location information. It said a software update has been planned to cease the backing-up.It is also planning to provide an update to limit the data storage on iPhone, in response to questions that the device has been storing location data since the release of iOS 4 operating system last June.Apple said it is a bug that iPhone keeps storing location data even if its location services are disabled, noting it will fix this through a software update in the coming weeks.The company also reiterated its focus on personal information security and privacy."Pretty much what I expected at this stage. The response is measured and the update should fix the problem," Alasdair Allan, one of the two British researchers who first announced the discovery of stored location data on iPhone, said on his Twitter account.ALLEGATIONThe statement on Wednesday is Apple's first official response to the location-tracking allegations.Worries on the iPhone tracking issue first surfaced last Wednesday when two British researchers announced at a technology conference in California that iPhone has been collecting users' location information and storing the data since June 21, 2010.Last Friday, The Wall Street Journal reported its security analysts had found that Apple's iPhone and smartphones running Google's Android operating system regularly transmit users' locations back to the two companies respectively, which is part of their race to build databases capable of pinpointing people's locations via smartphones.The newspaper then reported on Sunday that its analysts had also found iPhone is collecting and storing user's location data even when location services are turned off.PRESSUREThe Cupertino, California-based company has been facing mounting pressure from lawmakers, customers as well as media reports following the revelations.The U.S. House Energy and Commerce Committee on Monday sent letters to six developers of mobile device operating systems, including Apple and Google, demanding Apple's explanation on implications of alleged tracking for individual privacy and federal communications policy.Also on Monday, Minnesota Senator Al Franken, chairman of the U. S. Senate Judiciary Subcommittee on Privacy, Technology and the Law, announced he had scheduled a mobile privacy hearing on May 10 and asked representatives from Apple and Google to speak at the hearing.Meanwhile, Lisa Madigan, Attorney General of U.S. state of Illinois, on Monday called for a meeting with Apple and Google executives on the location-tracking reports, citing her ongoing effort to protect consumers' personal information online.Last Friday, two iPhone users filed a class action suit against Apple in Tempa, Florida, accusing the company of invasion of privacy and computer fraud and seeking a judge's order to bar the alleged data collection.Last Thursday, U.S. congressman Edward Markey asked Apple CEO Steve Jobs to make a response within 15 business days or no later than May 12, saying "Apple needs to safeguard personal location information of its users to ensure that an iPhone doesn't become an iTrack."On Saturday, Markey called for a congressional investigation into the privacy practices of Apple and Google. In a statement, he made clear that he thinks the data collection is potentially dangerous, saying predators could have hacked into an iPhone or Android phone to find out children's location information.Apple is also reportedly being investigated in South Korea, France, Germany and Italy over the alleged tracking practice.

WASHINGTON, April 6 (Xinhua) -- U.S. researchers have discovered two genes in which variation affects intake of caffeine, the most widely consumed stimulant in the world, according to a report described Wednesday in the open-access journal PLoS Genetics.A team of investigators from the National Cancer Institute, Harvard School of Public Health, Brigham and Women's Hospital, and the University of North Carolina at Chapel Hill examined genetic variation across the entire genome of more than 47,000 individuals from the U.S.They found the genes -- CYP1A2, which has previously been implicated in the metabolism of caffeine, and AHR, involved in the regulation of CYP1A2, played roles in regulating intake of caffeine. Individuals with the highest-consumption genotype for either gene consumed 40 mg more caffeine than those with the lowest-consumption genotype, equivalent to the amount of one-third cup of caffeinated coffee, or one can of cola.Caffeine is implicated in numerous physiological and medical conditions; it affects sleep patterns, energy levels, mood, and mental and physical performance. The identification of genes that have an impact on daily consumption offers opportunities to better understand these conditions. Further exploration of the identified genetic variants may provide insight into the speed of caffeine metabolism, how long caffeine circulates in the blood, or how strong the physiological effects of consuming a given amount of caffeine are.

MADRID, Jan. 24 (Xinhua) -- The Spanish branch of Industrial and Commerce Bank of China (ICBC) was officially inaugurated in Madrid Monday.ICBC President Jiang Jianqing, Spanish Minister of Industry, Tourism and Commerce Miguel Sebastian and Chinese Ambassador to Spain Zhu Bangzao attended an inaugural gala dinner here.In a speech, Jiang thanked the Spanish government and authorities for allowing the ICBC to open in Spain and highlighted the importance of the Spanish economy and the close relations between the two countries.Sebastian said Spain welcomes the arrival of the biggest Chinese bank, which would further improve the already good relationship between the two counties.The Madrid branch is to provide a wide range of financial services to 166,000 Chinese nationals living in Spain.ICBC has a total of 386,723 employees and 162 foreign branches throughout the World.

BEIJING, March 22 (Xinhuanet) -- An autopsy began Monday on Berlin zoo's superstar polar bear Knut who died suddenly on Saturday, media reports said.However, it remained unclear when the results from the post-mortem examination of Knut would be published."I cannot give you a timeline. We will inform the public when we know what the exact cause was," AFP quoted spokeswoman Claudia Bienek as saying.Knut died while sunbathing at Berlin zoo in Germany in front of visitors. The four-year-old swivelled around several times before falling backwards into the water in his enclosure.Witnesses said he suffered a series of convulsions and appeared to have had an epileptic fit or a heart attack.Knut was born in 2006 to a female bear who rejected him at birth. He was hand-raised by his keeper at the zoo. Films were made about him and he appeared on the front cover of Vanity Fair magazine and earned the zoo about 7.11 million U.S. dollars.More than 15,000 Knut fans have so far paid tribute to him on Berlin zoo's website. Hundreds more have flocked to the zoo in person to lay flowers at his enclosure.

来源：资阳报