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SAN DIEGO (KGTV) — As the federal government failed to pass a new spending measure to fund several agencies through the new year, a partial government shutdown went into effect late Friday.TSA agents in San Diego, categorized as essential employees, will return to work Saturday but without pay under the partial shutdown. Many other employees will also be required to work without pay, including: The Department of Homeland SecurityThe Justice DepartmentThe Interior DepartmentThe State DepartmentThe Department of Housing and Urban Development"Mortgages, car payments, things of that nature, Border Patrol agents will have to find a way to make ends meet, even while they're not receiving their paychecks," Joshua Wilson, vice president of the National Border Patrol Council, told 10News. Though, Wilson added a shutdown was worth ensuing more border security for him and other agents. "It's about darn time Congress do something about border security. They keep punting, and we're very, very tired of it. We want their support they have we have the support of this adminstration."RELATED: Holiday-season gridlock in DC brings partial federal closureAbout 380,000 total federal non-essential employees could be placed on furlough, or essentially placed on leave without pay until the government shutdown ends. The Internal Revenue Service, NASA, and the National Park Service will likely see employees furloughed, the latter of which could be seen as San Diego's Cabrillo National Monument closed Saturday. Many national parks area expected to close during the shutdown.Congress could order retroactive payments to furloughed employees after the shutdown, but that isn't guaranteed.We asked our 10News Facebook audience how the government shutdown will affect them: 1775

SAN DIEGO (KGTV) - Attendance may have dipped at one of San Diego's biggest tourist destinations, but it may not be doom and gloom for the theme park.A new report from the Themed Entertainment Association shows Americans are heading out for fun at top parks around the U.S. The report says the country's top 20 parks saw a 2.3 percent increase overall in 2017.In San Diego, however, the draw to get people into parks wasn't nearly as positive.RELATED: SeaWorld San Diego's new Electric Eel roller coaster opens to the publicSeaWorld San Diego had 3.1 million visitors in 2017, a 13.9 percent drop from 2016's attendance of 3.6 million. The park did report a 15 percent increase in attendance and 16 percent increase in revenue across all parks in the first quarter of 2018. The report stated: 815

SAN DIEGO (KGTV) — Bernie Sanders is showing his support for dozens of hotel workers on strike over their pay and benefits. The former presidential candidate stood alongside protestors at The Westin Hotel on Friday. “Nobody wants to do this. We would all like to work right now,” says employee Arturo Ramirez.Ramirez has been working at The Westin Hotel since February. With the high cost of living in San Diego, Ramirez says its sometimes hard to pay the bills.“My mother and I, we work at the same hotel. We’re struggling to pay ,100 in rent," Ramirez says.Bernie Sanders took the stage to show his support to workers during his visit to San Diego.“We’re saying to Marriott who owns Westin, we’re saying to every corporation in this country who make billions of dollars in profit, pay your workers a living wage," Sanders said to a crowd of protesters.Employees are asking for a raise of at least an hour and a chance to save for their retirement.“It’s a billion dollar company that needs to pay the workers a living wage so they can live in the city of San Diego," says Bridgett Browning, President of Unite Here Union. Browning says employee wages at The Westin are lower than competing hotels. Unite Here union says they will go into negotiations with The Westin Hotel on Monday.10News reached out to the hotel, we are still waiting for a response.  1388

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

SAN DIEGO (KGTV) -- Caltrans is warning drivers about a series of SR-163 closures throughout the week. According to the agency, all lanes of north and southbound SR-163 between I-8 and Genesee Avenue for three to six nights. The highway will be closed so crews can remove falsework from the bridge on the SR-163 Friars Road overcrossing. The southbound closures will begin at 11 p.m. with the northbound closures starting at 11:30 p.m. All lanes will reopen at 5 a.m. The list below shows which lanes will be closed on certain nights: Sunday: All southbound lanes, the northbound far right collector lane and the right main lane (slow lane).Monday: No full freeway closure. Only the northbound and southbound right main lanes.Tuesday: All southbound lanes, and the northbound left lane (fast lane).Wednesday: All northbound lanes, and the southbound left lane.Thursday: No full freeway closures. Only the northbound right lane.Friday/Saturday: No freeway work scheduledSunday, March 10: All northbound lanes. During the closures, drivers on the northbound SR-163 will be rerouted to eastbound I-8 to northbound I-805 to the merge at northbound SR-163.Southbound motorists will be rerouted to southbound I-805 to westbound I-8 to the southbound SR-163 connector ramp. 1274

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