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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871
KATOWICE, Poland (AP) — Arnold Schwarzenegger says he wishes he could travel back in time like the cyborg he played in "The Terminator" so he could stop fossil fuels from being used."If we would've never started in that direction and used other technology, we'd be much better off," the actor and former California governor said Monday at the start of a U.N. climate conference in Poland."The biggest evil is fossil fuels: it's coal, it's gasoline, it's the natural gas," he told conference delegates.Schwarzenegger also insisted that the United States was "still in" an international accord to curb global warming despite U.S. President Donald Trump's decision to walk away from the agreement.Calling Trump "meshugge" - Yiddish for "crazy" - for abandoning the accord, Schwarzenegger said the 2015 agreement has widespread support at the local and state levels even if the federal government isn't on board.American states, cities, businesses and citizens can do a lot to curb global warming, and representatives from those arenas should be invited to next year's climate conference, he told the audience in Poland."And if you do that, I promise you: I'll be back," he said in another reference to "The Terminator."Schwarzenegger later told The Associated Press he has converted his signature Humvee trucks to run on hydrogen, electricity and biofuel and only allows himself to eat meat three days a week."I mean, maybe it tastes delicious, but I think we should think then and there before we eat about the world and about the pollution," he said. "So I discontinued eating meat four days a week. And eventually, maybe we'll go to seven days" 1652
LA JOLLA, Calif. (KGTV) -- A group of San Diego conservationists is testing a high-tech approach to catch poachers illegally fishing in marine protected areas.The Imperial Beach-based non-profit Wildcoast is in the midst of a pilot study with the Scripps Institution of Oceanography to examine the effectiveness of land-based radar as a real-time monitoring tool for law enforcement.A single radar station can send a signal up to three miles and detect vessels as small as a kayak, said Wildcoast conservationist Cory Pukini."Enforcement officers will be able to open up a laptop or look at their cell phone to see if people are in compliance without actually deploying resources to come out here," Pukini said while boating through one of the marine protected areas (MPAs).There are 11 MPAs in San Diego County which have restrictions on fishing, including one near Crystal Pier in Pacific Beach and another near the La Jolla Children's Pool. The areas are designed to help fish populations rebound, provide a buffer zone for the effects of climate change, and preserve other resources.A new law that took effect this year allows wardens to issue heftier fines to people caught fishing for profit in an MPA. The penalty for a first offense now ranges from ,000 to ,000, up from 0 to ,000. Although wardens have issued more fines and warnings in recent years, enforcement remains elusive. The California Department of Fish and Wildlife has just one boat and five wardens to patrol 18 MPAs in San Diego and Orange Counties. That's where the land-based radar and app could make an impact, according to Pukini."It'll help them more efficiently deploy resources to the field," he said.Together with ocean temperatures and weather data, information gathered by the radar could be used to forecast the times and locations where poaching is most likely, Pukini said. The Marine Monitor Radar Project study is in its second year. If it's shown to be effective, the approach could help protect marine preserves around the world, Pukini said. 2050
JUNEAU, Alaska — Health officials in Alaska have reported that a second health care worker had an adverse reaction to a COVID-19 vaccine.Bartlett Regional Hospital in Juneau says the two workers showed adverse reactions about 10 minutes after receiving the vaccine and were treated. One received the vaccine Tuesday and will remain in the hospital another night under observation while the other, vaccinated Wednesday, has fully recovered.U.S. health authorities warned doctors to be on the lookout for rare allergic reactions when they rolled out the first vaccine, made by Pfizer and Germany’s BioNTech. In the U.S., vaccine recipients are supposed to hang around after the injection in case signs of an allergy appear and they need immediate treatment — exactly what happened when the health worker in Juneau.The CDC said it is aware of the incident."Anaphylaxis is a rare event following vaccination and CDC is evaluating the case," the CDC said in a statement. "CDC and public health experts prepared for a side effect like this after reports of anaphylaxis were made in England. Appropriate medical treatment for severe allergic reactions must be immediately available in the event of an anaphylactic reaction occurs, the CDC said. Britain had reported a few similar allergic reactions a week earlier.Allergies are always a question with a new medical product, but monitoring COVID-19 vaccines for any other, unexpected side effects is a bigger challenge than usual.It’s not just because so many people need to be vaccinated over the next year. Never before have so many vaccines made in different ways converged at the same time — and it’s possible that one shot option will come with different side effects than another.Getting either the Pfizer-BioNTech shot or the Moderna version can cause some temporary discomfort, just like many vaccines do.In addition to a sore arm, people can experience a fever and some flu-like symptoms — fatigue, aches, chills, headache. They last about a day, sometimes bad enough that recipients miss work, and are more common after the second dose and in younger people.These reactions are a sign that the immune system is revving up. COVID-19 vaccines tend to cause more of those reactions than a flu shot, about what people experience with shingles vaccinations. 2312
KINGSVILLE, Texas (AP) — The U.S. Navy has welcomed its first Black female Tactical Aircraft pilot.The Navy on Thursday recognized that Lt. j.g. Madeline Swegle had completed naval flight school and would later this month receive the flight officer insignia known as the “Wings of Gold.”The Naval Air Training Command tweeted that Swegle is the Navy’s “first known Black female TACAIR pilot.”According to Stars and Stripes, Swegle is from Burke, Virginia, and graduated from the U.S. Naval Academy in 2017.Officials say she is assigned to the Redhawks of Training Squadron 21 in Kingsville, Texas. 605