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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

Former Fleetwood Mac singer and guitarist Lindsey Buckingham is suing the band for making him go his own way.In court documents obtained by CNN, Buckingham claims that lost an estimated million in upcoming tour proceeds?after he was involuntarily expelled from Fleetwood Mac in January. He is suing Stevie Nicks, Christine McVie, John McVie and Mick Fleetwood for breach of fiduciary duty and breach of oral contract.It's not entirely clear what led to Buckingham's departure from the group, though his suit outlines debate about touring schedules.Fleetwood Mac was originally founded in 1967 by Peter Green and was named after two of its band members, Fleetwood and John McVie. Green left the band in 1969. Buckingham joined in 1974, the same year as Nicks, Fleetwood Mac's lead singer.Buckingham wrote some of the band's most well-known songs, including "Go Your Own Way," which was the lead single off the band's highly successful 1977 album, "Rumours."Fleetwood Mac has had a tumultuous history. The group took a hiatus in 1982 and when they agreed to go back on tour in 1987, Buckingham backed out at the last minute. In 1998, Christine McVie left the band and later rejoined in 2014."Everything that we wore on our sleeve, the discord and nature of the band, was the people breaking up, the dysfunction," Buckingham told CNN at a MusiCares event, days before he found out the band would be touring without him. "Right below all of that dysfunction is a great, great deal of love."CNN has reached out to Buckingham and Fleetwood Mac's representatives for comment. 1585

For the first time in its history, Sports Illustrated will feature a transgender model in its annual Swimsuit Edition.Sports Illustrated said Friday that 23-year-old Brazilian model Valentina Sampaio would be featured in the magazine, which is slated for a July 21 release.In an open letter published on Sports Illustrated's website, Sampaio said she was "excited and honored" to be a part of the upcoming issue."Being trans usually means facing closed doors to peoples’ hearts and minds," she wrote. "We face snickers, insults, fearful reactions and physical violations just for existing. Our options for growing up in a loving and accepting family, having a fruitful experience at school or finding dignified work are unimaginably limited and challenging.""I recognize that I am one of the fortunate ones, and my intention is to honor that as best I can."According to NBC, the Swimsuit Edition is just the latest barrier Sampaio has smashed as a transgender model. Last year, she was hired as the first openly trans Victoria's Secret model, and she was the first openly trans model to appear on the cover of any Vogue magazine."Valentina has been on our radar for some time now and when we finally met face-to-face it became apparent that besides her obvious beauty, she is an impassioned activist, a true pioneer for the LGBT+ community and just simply embodies the well-rounded woman we are proud to have represent SI Swimsuit across our platforms," Sports Illustrated said in a statement to NBC.In 2019, Sports Illustrated featured a Muslim model, Halima Aden, in the Swimsuit Edition. Aden sported a hijab and a burkini in her photo shoot. 1653

Former NFL running back Kareem Hunt was accused of kicking a man at a nightclub in Kansas City, Missouri, in January 2018.The incident is the latest to come to light allegedly involving Hunt since video surfaced Friday showing him physically assaulting a woman in February. Three incidents of violence involving Hunt have been documented this year.No charges were filed in any of the cases. The Kansas City Chiefs released Hunt on Friday after TMZ posted the video. Hunt asked for forgiveness Sunday in an ESPN interview and admitted to lying to the Chiefs about the incident."I'm asking for forgiveness and I definitely believe I deserve forgiveness," Hunt told ESPN. "Everything is really happening fast right now, and I just want everybody to forgive me."Here is what we know about three incidents in which Hunt's name came up in 2018. 846

First lady Melania Trump spoke out against cyberbullying Monday as part of her Be Best campaign, warning against "destructive and harmful" uses of social media and once again highlighting a messaging rift between the East Wing and the West Wing."In today's global society, social media is an inevitable part of our children's daily lives," Trump said at a cyberbullying summit in Rockville, Maryland. "It can be used in many positive ways, but can also be destructive and harmful when used incorrectly. This is why Be Best chooses to focus on the importance of teaching our next generation how to conduct themselves safely and in a positive manner in an online setting."At the same time, President Donald Trump was on Twitter, railing against John Brennan, whom he called a "hack" and "the worst CIA Director in our country's history" as summit panelists discussed the need for adults to be "good digital role models" for children. Despite firing off multiple tweets Monday morning, none were about the first lady's Be Best initiatives or her speech.The President's well-known Twitter habit, exemplified last week by his harsh attack on former White House aide Omarosa Manigault Newman, has drawn criticism and highlights the seeming disconnect between the East Wing and the West Wing."When you give a crazed, crying lowlife a break, and give her a job at the White House, I guess it just didn't work out. Good work by General Kelly for quickly firing that dog!" he tweeted.The first lady's spokeswoman sought to downplay any disconnect between the East Wing and the West Wing, calling the first lady "independent.""She's addressed this before. She is well aware of the criticism, but that will not deter her from doing what she feels is right. I would hope most people in this country are proud that they have a strong and independent first lady who only has the best interests of children at heart -- I know I am," the first lady's communications director Stephanie Grisham told CNN.In a White House with a President who makes his own rules -- especially on social media -- his wife has faced criticism for being unable to curb her own husband's behavior. Instead, she's made an independent choice to do what she can."She is aware of the criticism but it will not deter her from doing what she feels is right. The President is proud of her commitment to children and encourages her in all that she does," Grisham said in a statement.Responding to the apparent hypocrisy between the first lady's assertion that social media can be "destructive and harmful when used incorrectly" and the President's own habits, Grisham deflected."Rather than dissecting her remarks, let's focus on the countless children who struggle w bullying & online safety each day," she tweeted.She later described Trump's advocacy against cyberbullying as "a sincere campaign meant to help children."During her speech, the first lady acknowledged that children can be more aware of the "pitfalls" of social media than adults."Let's face it: most children are more aware of the benefits and pitfalls of social media than some adults, but we still need to do all we can to provide them with information and tools for successful and safe online habits," she said. 3246

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