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EL CAJON (CNS) - The California Highway Patrol is investigating a fatal traffic collision in the 13500 block of Piping Rock Lane near El Cajon, authorities said today.At least one person has died, according to a dispatcher with the California Highway Patrol's Border Communications Center.The agency was notified of the crash by Heartland Fire & Rescue at 9:45 p.m. Saturday.CHP investigators were still on scene at 12:15 a.m. El Cajon police did not respond to the incident, as it occurred outside the city's boundaries, an El Cajon Police Department dispatcher said.The cause was under investigation. 614

DOHA, Qatar (AP) — The United States and the Taliban have signed a peace agreement aimed at ending the 18-year war in Afghanistan, America's longest. The signing could help President Donald Trump fulfill a key campaign promise to extract America from its “endless wars.” Under the agreement, the U.S. will begin withdrawing thousands of troops in exchange for Taliban commitments to prevent Afghanistan from being a launchpad for terrorist attacks.If the Taliban meet their commitments, all U.S. troops would leave in 14 months. The U.S. invaded Afghanistan after the Sept. 11, 2001 attacks to overthrow the Taliban, who had hosted Osama bin Laden and al-Qaida as they planned and celebrated the assault.The agreements are considered the first step for talks with Afghan factions, which are likely to be complicated. Under the agreement, the Afghan government would release 5,000 Taliban fighters, but it's unclear whether the government will do that. It's also unclear whether those fighters will abide by any peace deal, the Associated Press reported.The complete withdrawal of American troops would not depend on any specific outcome in talks between Taliban and other Afghan factions, the AP reports.In Qatar, U.S. Secretary of State Mike Pompeo met with the Taliban, where the group has a political office, but did not sign the agreement. The agreement was signed by U.S. peace envoy Zalmay Khalilzad and Taliban leader Mullah Abdul Ghani Baradar.Pompeo told reporters that the U.S. is “realistic” about the deal, but is “seizing the best opportunity for peace in a generation.”The Associated Press contributed to this report. 1639

Dr. Anthony Fauci, who has become America’s doctor during this tumultuous coronavirus pandemic, says he will be celebrating his upcoming 80th birthday and Christmas holiday without his three adult daughters or other extended family or friends.“I'm going to be with my wife — period,” Fauci told the Washington Post’s “Power Up” during an interview this week.“The Christmas holiday is a special holiday for us because Christmas Eve is my birthday. And Christmas Day is Christmas Day. And they are not going to come home … That's painful. We don't like that.He said as painful as it is, that’s just something we have to accept during this “unprecedented challenging time.”He reminded Americans we cannot treat this like “business as usual this Christmas” because we could “make it worse if we don’t do something about it.”America has seen record-breaking surges in coronavirus infections and deaths following the Thanksgiving holiday, when millions traveled and gathered with people outside their household.“We have a big problem,” Fauci told the Washington Post. “Look at the numbers - the numbers are really quite dramatic.”The CDC urged people to stay home for Thanksgiving to slow the spread of the coronavirus, and they have repeated their pleas for the December holiday season.“Celebrating virtually or with members of your own household (who are consistently taking measures to reduce the spread of COVID-19) poses the lowest risk for spread,” the CDC states in their holiday guidelines.But telling loved ones you won’t be coming for dinner, or that party, or that small gathering, can be emotionally and physically difficult.Fauci says try putting things into perspective.“Maybe this is a time to just say, 'This is an unusual situation, it's not going to last forever, it is highly likely that with vaccines being distributed, that we will be back to normal by next Christmas,’” he said.For those who are traveling, Fauci warned that a “negative (test) today doesn’t mean that you’re going to be negative tomorrow,” and that additional measures like isolation, mask-wearing and social distancing need to be practiced. 2132

Due to the wildfires raging in Northern California, San Francisco, Stockton and Sacramento were the world's three "most polluted cities" on Friday morning, according to Berkeley Earth, a nonprofit that aggregates data from air-quality monitoring sites.PurpleAir, which has a network of sensors around the world, also showed that California had worse air than traditional smog hotspots in India and China.CNN meteorologist Brandon Miller confirmed that "no region on Earth had as many air quality stations in the highest ranges" of particulate matter, or PM, the toxic mixture of particles and droplets that worsens after wildfires.Those values, he said, "stretched for hundreds of miles over Northern and Central California, from the mountains to the valleys and the coast."Schools, colleges and public transit have closed as smoke from the Camp Fire descends on the region."It appears to be the worst air quality ever experienced in San Francisco," said Dan Jaffe, a professor of environmental chemistry at the University of Washington. He called the situation "an air quality emergency," and experts said the smoke could undo decades of progress on pollution."We have made tremendous efforts and investment to clean up our air with considerable benefits for public health," said Dr. Daniel Jacob, a professor of atmospheric chemistry and environmental engineering at Harvard University. "But now it's like we're getting stabbed in the back with those wildfires." 1472

Donna and Sam Van Why are adjusting to a new lifestyle. Several years ago, after signs of failing short-term memory, doctors informed the couple that Donna was dealing with a neurocognitive disorder that’s possibly Alzheimers. Sam is now her primary caregiver.“I have a long ways to go in getting my cooking up to where Donna was before,” Van Why said.According to the Alzheimer’s Association, more than 5 million Americans are living with Alzheimer’s disease. Director of Scientific Engagement Rebecca Edelmayer says the disease causes progressive memory and function loss due to nerve cell death that happens in the brain. This leads to stages of dementia.“Dementia are those symptoms that people are experiencing outwardly," Dr. Edelmayer said. "So this could be changes in their memory or their thinking. It could also be changing in their personality or some of their behaviors. Like they may have issues with depression, or agitation, or even sleep disturbances.”Currently, there’s no treatment for Alzheimer’s, but research is moving at a fast pace and Van Why is always thrilled to hear about any new discoveries.“We may not be to the point of the solved vaccine for Alzheimer’s, but these steps are tremendous,” Van Why said.Aside from treatment, preventing the disease in the first place would be substantial progress and getting a yearly flu shot could be an answer.“New research presented at the Alzheimer’s Association International Conference suggests that flu and pneumonia vaccines may be associated with a lower risk of Alzheimer’s,” Dr. Edelmayer said.Fourth-year medical student Albert Amran made the discovery when pulling medical history of nearly 40,000 people in a national database. He says he and his colleagues at McGovern Medical School at UT Health in Houston looked at patients' charts focusing on drug history to see if anything could be repurposed to reduce the risk of Alzheimer’s disease. The influenza vaccination popped out.“What we’re thinking is happening that as people get older the people who gets shots essentially are keeping their immune systems in shape,” Amran said.However, it should be noted that this research isn’t conclusive. Amran says it’s all very new and needs to be observed in a clinical study. Edelmayer suggests the risk reduction for Alzheimer’s could even be from a completely different factor.“It’s very possible that these are indirect effects," Dr. Edelmayer said. "That people who are getting vaccinated also take care of their health in other ways. And things could really add to a lower risk of Alzheimer’s and other dementias.”Amran says the next step is seeing if these findings can be confirmed in different populations. In the meantime, families feeling the effects of Alzheimer’s are doing what they can to help the ones they love while waiting for a treatment or cure.“I am trying my best to stay in the house or with Sam. I’m lucky I got him,” Donna Van Why said. 2944