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SAN DIEGO (KGTV) — Independent reviews by the FDA show the COVID-19 vaccines by Pfizer and Moderna have similar levels of safety and efficacy, although there are early indications of potential differences.Both vaccines rely on the same basic approach: jumpstarting the immune system with messenger RNA. The FDA confirmed their overall efficacy is essentially identical; 95 percent for Pfizer and 94.1 percent for Moderna.However, signals in the data suggest Moderna’s vaccine may better protect against severe cases of COVID-19, while Pfizer’s vaccine may work better in adults over 65. But experts warned those differences may just be statistical illusions.In Moderna’s study of 30,000 volunteers, 30 people got severe cases of COVID-19. All 30 of those cases were in the placebo group, suggesting the vaccine offers powerful protection against the most serious symptoms.In Pfizer’s trial of 44,000 volunteers, one vaccinated person got a severe case compared to 10 people in the placebo group.“We still need more data,” said Dr. Abisola Olulade of Sharp Rees-Stealy. “It's not a reason to recommend one versus the other.”In adults over 65, the efficacy of Moderna’s vaccine dipped slightly to 86.4 percent. Pfizer’s vaccine was 92.9 percent effective in people aged 65 to 74 and 100 percent effective in individuals 75 and up.“When I think people in the community look at that number, they might say, ‘Oh, that Moderna vaccine probably isn't as good for the older population compared to the Pfizer vaccine.’ But as a clinician looking at numbers, they're both amazing,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.FDA scientists found both vaccines are safe but short-term side effects are common, especially with Moderna’s drug. Both vaccines are administered in two doses. The table below lists the percentage of vaccinated volunteers who reported a side effect after either dose, although side effects were most common after the second injection.Side effect Moderna PfizerFatigue 68.5% 62.9%Headache 63.0% 55.1%Muscle pain59.6%38.3%Joint pain44.8%23.6%Chills43.4%31.9%Fever14.8%14.2%Typically the symptoms went away in one day.“Just because a vaccine has side effects doesn’t mean it’s not safe,” said Dr. Olulade. “We know that side effects happen actually because your immune system is working and waking up. It's actually a positive thing.”The slight difference in side effects could be because of differences in the way researchers polled volunteers, or it could be something with the architecture of the vaccines, experts said.The companies use different tiny bubbles of fat to enclose the messenger RNA. Moderna’s bubble is a little stronger and more stable so it doesn’t need to be stored at sub-arctic temperatures.“It could be that [Moderna’s] elicits a little more inflammation than the other,” Dr. Chin-Hong said.Having slightly more side effects could be a sign that Moderna’s vaccine prompts a stronger immune response that might lead to longer-lasting immunity, but the durability of either vaccine remains one of the most pressing unanswered questions.The biggest difference may be where the vaccines are deployed. Since Pfizer's vaccine needs to be stored at such cold temperatures, experts said Moderna's vaccine may be prioritized for rural hospitals and community health centers that lack ultra-cold storage units. 3370
SAN DIEGO (KGTV) — If you're single in San Diego, chances are you're not impressed by the dating field locally.At least according to Apartment List, which ranked 130 cities on their ability to provide singles with the best atmosphere. San Diego is, well, lukewarm according to the study.The city ranked 73 overall, right in the middle of the park and posting an overall score of 48 out of 100 possible points.RELATED: Love hurts: Price of a date in San Diego could cost you, study saysThe study ranked cities on their dating satisfaction, social satisfaction, dating affordability, and percentage of reported singles, using data from Apartment List’s Annual Renter Satisfaction Survey and Census Bureau American Community Survey 2017.When it broke down that way, only about 22% of respondents were satisfied with the dating in San Diego. How women and men feel about dating locally may give us an idea about why the city ranked where it did. About 17% of women and 35% of men were satisfied with dating here.Far more San Diegans, about 58%, were satisfied with their social lives in town. And looking at census data, the city posted a measly 22 out of 100 for percentage of singles.RELATED: Ideas for a first date in San DiegoAccording to Apartment List, San Diego's lacking singles population and low satisfaction rate with dating here don't make it an inviting city for singles. The price of dating in California is also abysmal.But social lives are thriving.Atlanta ranked as the best city for singles, followed by Madison, Wisc.; Washington, D.C.; Bloomington, Ind.; and New Orleans, La. Heading up the bottom of the list was a handful of California cities: San Bernardino, Calif.; Bakersfield, Calif.; Anaheim, Calif.; Fayetteville, N.C.; and lastly Stockton, Calif. 1779

SAN DIEGO (KGTV) - Looking for more space for your money? The Del Cerro and Torrey Highlands are the best San Diego neighborhoods for renters, according to HotPads.Analysts evaluated rental size and price per square foot. San Diego’s median rental size is 1,154 feet, and renters can expect to spend .32 per square foot of space.The median rental size in Torrey Highlands is 2,033 square feet, at .14 per square foot, HotPads reported. Del Cerro residents pay .77 per square foot, with a median rental size of 1,710 square feet. Rancho Pe?asquitos, Miramar Ranch North (Scripps Ranch), and the South Bay neighborhood of Ocean Crest are also in the top five communities with the most space for the money.RELATED: Report: San Diego seeing housing price cutsLas Vegas, a top destination for San Diegans who choose to leave the city, has some of the largest rentals and the most affordable rents. Raleigh, North Carolina, is also a good value, according to HotPads analysts.Denver and Boston have the smallest rentals for the money, averaging about 1,050 square feet. By comparison, Los Angeles and San Francisco average at 1,200 square feet.Size matters, but not as much as price. A Zillow Group Consumer Housing Trends Report showed 82 percent of renters named affordability as a top concern, 42 percent said finding the right size rental was extremely or very important.RELATED: The 10 fastest-growing metro areas 1431
SAN DIEGO (KGTV) - In celebration of National Pool Opening Day and in anticipation of the summer season, San Diego leaders will hold a community water safety festival Saturday.The 10th annual "April Pools Day" event will be held at Bud Kearns Pool, at 2229 Morely Field Dr., featuring swim assessments, CPR demonstrations, and safety presentations to educate about safe water practices.The event will also hold a cannonball kickoff and giant inflatable obstacle course for kids.RELATED: National Pool Opening Day signals summertime swimmingThe community water festival is aimed at waterproofing San Diego, through a multi-step approach to drowning prevention, swimming lessons, and beach safety training.As San Diego readies itself for the summer, the Prevent Drowning Foundation of San Diego will also hold a number of free swimming lessons and CPR demonstrations around the county. A full list can be found on the organization's website. 952
SAN DIEGO (KGTV) -- Like so many businesses throughout San Diego County, businesses along the border in San Ysidro are also preparing to scale back operations because of the state's COVID-19 purple tier.Businesses in the border region have already seen a significant decline in business because of international travel restrictions currently in place. Since March, the border has been closed to all tourist travel, only open for essential needs, like going to work or getting medical care. Tuetano Taqueria is one of the businesses affected. Just blocks from the border, its owners are doing everything it can to stay open. The trendy taco shop is run by Fernando Covarrubias and his wife, Chef Priscilla Curiel. During the initial stay-at-home order, the couple had to lay off their employees and run the business themselves. The taqueria was recently honored, making the Michelin Guide, famous for it's tacos served with the option of bone marrow on the side. Now, the owners are getting ready to scale back to takeout orders because of the purple tier restrictions. According to the San Ysidro Chamber of Commerce, from March to July, roughly 100 businesses closed permanently. Jason Wells, the chamber's executive director, said the border travel restrictions are devastating the region. Wells said all businesses in the area are hurting, but retail has taken the biggest hit. According to Wells, about 95% of customers in the area are from Mexico.Wells explained that most of the businesses along the border make their biggest profits during the holidays, and the state's purple tier isn't helping. If the border travel restrictions continue, Wells thinks more businesses will not survive. Covarrubias and his wife are hoping people will follow the health guidelines so COVID-19 case rates go down and business can get back to full operation. Despite their struggles, the couple is working on opening a second business in National City, called Mujer Divina, a coffee shop that will also serve burritos. Purple tier restrictions take effect Saturday at midnight. Border travel restrictions are in place until Nov. 21, but could be extended. 2153
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