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CANBERRA, Sept. 7 (Xinhua) -- A team of Australian and U.S. scientists on Wednesday said they discovered a genetic defect, which can lead to Leigh syndrome, a rare disorder which affects the central nervous syndrome.The scientists tested more than 1000 genes by encoding proteins active in two individuals who suffer from the illness. They used a new technique known as next-generation DNA sequencing to examine the genes.The gene they discovered encodes an enzyme which is found in the mitochondria which are subsets of cells. Without this enzyme the mitochondria do not translate proteins efficiently, and this then causes Leigh syndrome.According to David Thorburn, from the Murdoch Children's Research Institute in Melbourne, the discovery shows the enormous potential of the new technology."These findings demonstrate the ability of sequencing technologies to improve diagnosis," Professor Thorburn said in a statement released on Wednesday."Although it isn't clear in the case of Leigh syndrome whether the precise molecular diagnosis will necessarily lead to therapies, the current findings represent a meaningful service."He added that diagnosis of the disease along with its specific genetic cause can also be informative about the risk a couple has of having another affected child. The diagnostic information can help in decisions about whether and how to pursue alternative means of having children, for instance through the use of donor sperm or eggs.The research team consisted of scientists from Australia's Murdoch Institute as well as the Broad Institute in the U.S.In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of three. The problem is that the mitochondria responsible for powering their cells cannot keep up with the demand for energy in their developing brains.

BEIJING, Sept. 18 (Xinhua) -- No newly-formed oil belt was detected in the past two days in north China's Bohai Bay from ConocoPhillips' platforms in the Penglai 19-3 oilfield, the State Oceanic Administration (SOA) said.However, new spots of visible oil spills could still be found around platform C, the SOA said in a statement on Sunday.It is estimated that about 4.51 liters of oil leaked into the sea on Saturday, a slight drop from 6.56 liters from Thursday.No oil clean-up work was done on Friday and Saturday due to the strong winds and rough conditions at sea, the statement said.ConocoPhillips China, a subsidiary of U.S. energy giant ConocoPhillips, first reported spills to authorities in June. The oil spills have polluted more than 5,500 square km of sea water in the Bohai Bay since June.The oil spills have spread to beaches in Hebei and Liaoning provinces. The spills have been blamed for losses in the provinces' tourism and aquatic farming industries.The company on Aug. 31 submitted a report to the SOA claiming that it had screened out all potential sources for oil spills and blocked all oil leaks.After days of evaluation, however, the SOA said on Sept. 2 that ConocoPhillips had failed to complete the clean-up.

SAN FRANCISCO, June 21 (Xinhua) -- Database giant Oracle on Tuesday announced that it has entered into an agreement to acquire FatWire Software, a provider of web experience management solutions.FatWire's solutions provide organizations with ability to deliver relevant customer content, build community engagement and drive site stickiness and loyalty.It currently has more than 500 customers in industries, including finance, healthcare, manufacturing, media, retail, public sector and more. Its key customers include Wal-Mart, Best Buy, Ford and Pfizer.Oracle said in a statement that the acquisition is expected to help Oracle clients improve online engagement across web, mobile and social channels, through website optimizations.The transaction is expected to close mid-year 2011 and the financial details were not disclosed. In its recent acquisitions, Oracle acquired e-commerce software company Art Technology Group for 1 billion U.S. dollars.

HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.

WELLINGTON, Sept. 27 (Xinhua) -- New Zealand and Japanese scientists are teaming up to develop healthier foods under two government-funded "functional foods" projects.One project, to be led by New Zealand's Massey University, will work with New Zealand food companies to create and develop a functional food with specific health enhancing effects for menopausal women, New Zealand Science and Innovation Minister Wayne Mapp announced Tuesday.The other project, to be led in New Zealand by Plant and Food Research, would use mass spectrometry to develop a "metabolic atlas" of the chemical composition of allium vegetables, such as onions and garlic, which the horticultural industry could use to develop new food products with health benefits.Mapp said the two research projects would be awarded a total of 1 million NZ dollars (782,000 U.S. dollars) in funding to strengthen collaborative research relationships between New Zealand and Japan, Mapp said."These research projects have strong commercial potential, including through the Japanese market, and so have the potential to benefit our economy," said Mapp."The government is committed to building and strengthening research relationships with other countries that will achieve world-class scientific results and lead to new innovative technologies."The two projects awarded funding under Ministry of Science and Innovation's Japan Science and Technology Agency (JST) funding round focus on functional foods. The ministry and Japan each fund half the cost of each research project awarded funding.