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COPENHAGEN, June 7 (Xinhua) -- The outbreak of infections caused by E. coli bacteria may be over in Denmark as no new cases have been reported here since Friday.According to Denmark's National Serum Institute (NSI), there are 18 confirmed cases of severe intestinal infection caused by exposure to the bacteria as of Monday. No new infections have been reported since Friday, it added.The confirmed cases are said to consist of 10 men and 8 women aged between 23 and 81 years of age. Seven show symptoms of kidney failure which is associated with advanced stages of the infection.All but one are believed to have contracted the infection while traveling in northern Germany, where the outbreak started, the NSI said.So far, the E. coli infection has claimed 21 lives in Germany, which reports over 2,100 confirmed and suspected cases. It has also spread to 12 countries according to the World Health Organization (WHO)."This particular strain of E.coli has been identified in some people sporadically in the past, but it has not been known to have been associated with outbreaks in the past," a WHO spokesperson said Friday, adding it was a "very, very rare strain."Health authorities in Germany now suspect bean sprouts as the source of contamination in this outbreak, although this is yet to be confirmed.Dr Kaare Moelbak, an epidemiologist at NSI told Danish media Sunday that bean sprouts were a "very likely" source of contamination.Cucumbers were initially suspected and Denmark's food authority continues to warn against eating raw tomato, cucumber or lettuce from Germany until the source is established.Children are normally most vulnerable to E. coli infection but most of those infected in this outbreak are above the age of 20 years, Moelbak told Xinhua last week.He said children are likely less affected by this outbreak as they usually eat fewer salads than adults.In Germany, it is mostly women who have been affected by the infection. Moelbak explained the skew in infections saying women tend to choose to eat more vegetables than men, in comments made to Danish media Thursday.
SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.
SAN FRANCISCO, Sept. 13 (Xinhua) -- Researchers in San Francisco, U.S. have found in a latest study that bisphenol A (BPA) and methylparaben, two chemicals commonly used in consumer products, can interfere with the breast cancer drugs, local media reported on Tuesday.In the study, doctors from California Pacific Medical Center in San Francisco found that healthy breast cells from high-risk patients started to find ways to bypass breast cancer drugs after they were exposed to BPA and methylparaben in the lab.The cells exposed to the two chemicals kept growing and didn't die after they were introduced with Tamoxifen, a current standard drug therapy for female breast cancer and most common used treatment for male breast cancer, Dr. William Goodson, lead author of the study, told San Francisco Chronicle.Goodson said that BPA and methylparaben not only mimic estrogen 's ability to drive cancer, but appear to be even better than the natural hormone in bypassing the ability of drugs to treat it. The finds have been published online in the British medical journal Carcinogenesis.The research shows more evidence of safety issues of BPA, a chemical primarily used to make plastic baby bottles, food containers, household electronics and etc, as well as the less known methylparaben, a chemical preservative used in cosmetics and other personal care products.The researchers noted that the breast cancer rates have been growing by about the same amount in men as in women over the past three decades. Scientists have been looking at environmental causes for the disease and wondering where the hormones are coming from.Goodson said BPA and methylparaben are used so widely and even found in household dust, noting that it is still unknown whether the effects of exposure to the chemicals are reversible.Since 2008, several governments issued reports questioning the negative health effects of BPA, especially raising concerns regarding exposure of fetuses, infants and children. BPA use has been banned in baby bottles in a lot of countries and regions.As for methylparaben, the U.S. Food and Drug Administration said on its website that "at the present time there is no reason for consumers to be concerned about the uses of cosmetics containing parabens (including methylparaben)."
BEIJING, August 4 (Xinhuanet) -- Medtronic Inc. is giving Yale University a 2.5 million U.S. dollar grant to review the safety and effectiveness of its controversial spine treatment called Infuse Bone Graft, according to The Wall Street Journals Thursday.Under terms of the pact, the company will release to Yale and eventually the public what participants described as an unprecedented amount of clinical trial and other data. The university will select two research teams from other organizations to perform separate analyses of the data.The announcement comes in the wake of a paper in June in the Spine Journal. The paper revealed that several clinical studies of Infuse, conducted by surgeons with strong economic ties to Medtronic, failed to report serious complications that arose in the trials. The critical paper also found that many of the studies were designed in ways in favor of Infuse over a treatment given to a control group.Medtronic disputes some of the findings and is conducting an internal investigation of the matter.Infuse accounts for about 700 million dollars in annual sales for Medtronic. The product is under investigation by the Senate Finance Committee over the role payments to physicians who may have played how studies were reported.
BEIJING, Aug. 25 (Xinhua) -- China pledged on Thursday to make more efforts to aid people living in the drought-stricken Horn of Africa in collaboration with the International Committee for the Red Cross (ICRC)."We noticed that the ICRC launched an appeal regarding the situation in the Horn of Africa. The Red Cross Society of China (RCSC) has decided to donate 4 million yuan (about 623,000 U.S. dollars) to the ICRC for its humanitarian aid in the region," said Hua Jianmin, president of the RCSC, while meeting with visiting ICRC President Jakob Kellenberger in Beijing on Thursday.Earlier this month, the RCSC donated 8 million yuan (1.25 million dollars) to famine-plagued countries in the Horn of Africa to be used for emergency humanitarian aid.A donation of 2 million yuan was sent to Kenya through the country's Red Cross organization, while another 2 million went to Ethiopia. The other 4 million yuan was donated to other countries in the region.The Chinese government has decided to provide a total of 90 million yuan (14 million dollars) in emergency food assistance to countries in the Horn of Africa."The Red Cross Society of China is willing to work together with the International Committee for the Red Cross to meet the needs of those who have been affected (by the droughts)," Hua said.Some 12.4 million people in Kenya, Ethiopia, Somalia and other countries in the region are in dire need of food due to a serious drought, the worst to hit the region since the 1980s.