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The first experimental COVID-19 vaccine in the U.S. is on track to begin a huge study next month to prove if it really can fend off the coronavirus, while hard-hit Brazil is testing a different shot from China.Where to do crucial, late-stage testing and how many volunteers are needed to roll up their sleeves are big worries for health officials as the virus spread starts tapering off in parts of the world.Moderna Inc. said Thursday the vaccine it is developing with the National Institutes of Health will be tested in 30,000 people in the U.S. Some will get the real shot and some a dummy shot, as scientists carefully compare which group winds up with the most infections.With far fewer COVID-19 cases in China, Sinovac Biotech turned to Brazil, the epicenter of Latin America’s outbreak, for at least part of its final testing. The government of S?o Paulo announced Thursday that Sinovac will ship enough of its experimental vaccine to test in 9,000 Brazilians starting next month.If it works, “with this vaccine we will be able to immunize millions of Brazilians,” said S?o Paulo′s Gov. Joao Doria.Worldwide, about a dozen COVID-19 potential vaccines are in early stages of testing. The NIH expects to help several additional shots move into those final, large-scale studies this summer, including one made by Oxford University that’s also being tested in a few thousand volunteers in Brazil.There’s no guarantee any of the experimental shots will pan out.But if all goes well, “there will be potential to get answers” on which vaccines work by the end of the year, Dr. John Mascola, who directs NIH’s vaccine research center, told a meeting of the National Academy of Medicine on Wednesday.Vaccines train the body to recognize a virus and fight back, and specialists say it’s vital to test shots made in different ways — to increase the odds that at least one kind will work.Sinovac’s vaccine is made by growing the coronavirus in a lab and then killing it. So-called “whole inactivated” vaccines are tried-and-true, used for decades to make shots against polio, flu and other diseases — giving the body a sneak peek at the germ itself — but growing the virus is difficult and requires lab precautions.The vaccine made by the NIH and Moderna contains no actual virus. Those shots contain the genetic code for the aptly named “spike” protein that coats the surface of the coronavirus. The body’s cells use that code to make some harmless spike protein that the immune system reacts to, ready if it later encounters the real thing. The so-called mRNA vaccine is easier to make, but it’s a new and unproven technology.Neither company has yet published results of how their shots fared in smaller, earlier-stage studies, designed to check for serious side effects and how well people’s immune systems respond to different doses.Even before proof that any potential vaccine will work, companies and governments are beginning to stockpile millions of doses so they can be ready to start vaccinating as soon as answers arrive.In the U.S., a program called “Operation Warp Speed” aims to have 300 million doses on hand by January. Under Brazil’s agreement with Sinovac, the Instituto Butantan will learn to produce the Chinese shot.___AP journalist Marcelo Silva de Sousa contributed to this report.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3499
The Duke and Duchess of Cambridge are very pleased to share a new picture of The Duke with Prince George, Princess Charlotte and Prince Louis ahead of The Duke’s birthday tomorrow.The picture was taken earlier this month by The Duchess. pic.twitter.com/maFAGS4bTe— The Duke and Duchess of Cambridge (@KensingtonRoyal) June 20, 2020 339
The CDC reports that the number of flu cases is low right now, and it could be because of safety precautions to slow the spread of the coronavirus, including wearing masks and remaining distant from people in public. Also, high levels of flu vaccinations.The Centers for Disease Control and Prevention tracks flu vaccine distribution and shows, so far for the 2020-2021 season, just under 190 million flu vaccines have been distributed. This compares to about 174 million distributed during the whole 2019-2020 season.According to the CDC’s weekly “flu view” update, “seasonal influenza activity in the United States remains lower than usual for this time of year.”“Overall flu activity is low, and lower than we usually see at this time of year,” Dr. Daniel B. Jernigan, director of the influenza division of the Centers for Disease Control and Prevention, told the New York Times. “I don’t think we can definitively say there will be no twindemic; I’ve been working with flu for a long time, and I’ve been burned. But flu is atypically low.”However, they caution that flu activity may increase in the coming months. Flu season typically peaks at the beginning of the year, depending on the region.The CDC’s map showing state-by-state flu activity shows the majority of the country with “minimal” rates of flu activity, with Oklahoma at a low “moderate” level. A comparison to the 2019-2020 season showed two states were in the moderate level at this time.“The unprecedented demand we’ve seen for flu shots this season, along with safety precautions everyone is taking to limit the spread of COVID-19, such as social distancing, wearing facemasks and frequently washing their hands, may be contributing to lower flu activity this season,” Dr. Kevin Ban, the chief medical officer at Walgreens, said in a written statement.Related: Is it the flu or coronavirus? Walgreens is reporting fewer sales of antiviral medications for flu so far this season compared to 2019. The health and wellness company has a flu tracker each season that tracks regional activity.Health experts remind everyone it is not too late to get the flu vaccine and be protected for the 2020-2021 flu season. 2186
The first presidential debate of the 2020 election is behind us, but we still have two more coming up before Nov. 3, as well as a vice presidential debate.The single vice presidential debateThe next debate will be between the running mates, Vice President Mike Pence and Sen. Kamala Harris. The candidates for vice president will square off on Oct. 7 at the University of Utah in Salt Lake City.The debate will be moderated by Susan Page, the Chief of USA Today’s Washington Bureau.The event will be divided into nine segments, with about 10 minutes being spent on each. Page will ask an opening question, after which Pence and Harris will have two minutes to respond. Page will use the balance of the time in the segment for a deeper discussion of the topic.The second presidential debateThe next time President Donald Trump and former Vice President Joe Biden will face off will be on Oct. 15 at the Adrienne Arsht Center for the Performing Arts in Miami, Florida.The debate will be a town meeting-style event, moderated by Steve Scully, Senior Executive Producer and Political Editor at C-SPAN.The debate’s questions will be posed by citizens of the South Florida area. The candidates will have two minutes to respond to each question and there will be an additional minute for the moderator to facilitate further discussion.The town meeting participants will be uncommitted voters selected under the supervision of Dr. Frank Newport, Senior Scientist at Gallup.The third presidential debateThe third and final presidential debate of this cycle will be held just days before Election Day on Oct. 22. The event is set to take place at Belmont University in Nashville Tennessee and will be moderated by Kristen Welker, White House Correspondent for NBC News and weekend co-anchor of the Today Show.The format of this debate will be identical to the first, divided into six segments with about 15 minutes dedicated to major topics selected by the moderator. Welker will open each segment with a question and each candidate will have two minutes to respond. Trump and Biden will then have an opportunity to respond to each other.Changes to upcoming debatesThe day after the first debate, the Commission on Presidential Debates announced that there will be changes made “to ensure a more orderly discussion of the issues” at future debates this election season."Last night’s debate made clear that additional structure should be added to the format of the remaining debates to ensure a more orderly discussion of the issues," the commission said in a statement. "The CPD will be carefully considering the changes that it will adopt and will announce those measures shortly."The commission also said it's grateful to Chris Wallace for the "professionalism and skill" he brought to first debate, and they intend to ensure that additional tools to maintain order are in place for the remaining debates. 2905
The Center for Disease Control (CDC) has issued a reminder to the public to stop washing and reusing condoms.The CDC said in a tweet that this reminder to all sexually-active Americans was sent out "because people do it." 229