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WASHINGTON, April 4 (Xinhua) -- New research from the University of Pennsylvania School of Medicine has revealed an increased incidence of major adverse cardiac events (MACE), such as heart attack, stroke, and cardiovascular death, in patients with severe psoriasis. The study results were reported Monday at the annual American College of Cardiology meeting in New Orleans.Psoriasis is a common inflammatory skin disease, and if severe, has been demonstrated to be a risk factor for cardiovascular disease. However, the degree to which psoriasis is associated with MACE has not been defined.In a cohort study analyzing data from a general practice research database, Lead author Nehal Mehta, director of Inflammatory Risk in Penn's Preventive Cardiology program, and colleagues reviewed the case histories of over 3,600 patients with severe psoriasis and 14,300 controls. They found that patients with severe psoriasis have a 53 percent increased incidence of MACE compared to the general population. They also found that having a diagnosed case of severe psoriasis confers an additional ten-year risk of six percent on MACE.Previous work from Mehta and colleagues found that the risk of death from cardiovascular disease increased by 57 percent in patients with severe psoriasis. In addition, the relative risk of death from cardiovascular disease was even higher in younger patients, who were as young as age 40.The researchers conclude that this new estimate of increased ten-year MACE may warrant more aggressive strategies for treatment of cardiovascular risk factors in patients with psoriasis.
LOS ANGELES, April 3 (Xinhua) -- People with lower levels of vitamin D are more likely to have stiffer arteries and an inability of blood vessels to relax, U.S. researchers have found.This finding also applies to people who are in general good health, according to researchers from the Emory University School of Medicine.The researchers presented their findings on Sunday at the annual American College of Cardiology meeting in New Orleans.Impaired vascular health in correlation with lower vitamin D levels contributes to high blood pressure and the risk of cardiovascular disease, the researchers say.The study involved 554 participants, with the average age of 47 and generally healthy.The average level of 25-hydroxyvitamin D (a stable form of the vitamin reflecting diet as well as production in the skin) in participants' blood was 31.8 nanograms per milliliter. In this group, 14 percent had 25-hydroxyvitamin D levels considered deficient, or less than 20 nanograms per milliliter, and 33 percent had levels considered insufficient, less than 30 nanograms per milliliter.The researchers monitored the ability of participants' blood vessels to relax by inflating and then removing a blood pressure cuff on their arms. To allow blood to flow back into the arm, blood vessels must relax and enlarge -- a change that can be measured by ultrasound. The researchers also made other measurements of smaller blood vessels and examined the resistance to blood flow imposed by the arteries.
WASHINGTON, May 25 (Xinhua) -- The number of young adults in the United States with high blood pressure may be much higher than previously reported, according to a new study by researchers at the University of North Carolina (UNC) at Chapel Hill.Researchers analyzed data on more than 14,000 men and women between 24 and 32 years old in 2008 from the National Longitudinal Study of Adolescent Health, known as Add Health. They found 19 percent had elevated blood pressure, also referred to as hypertension. Only about half of the participants with elevated blood pressure had ever been told by a health-care provider that they had the condition."The findings are significant because they indicate that many young adults are at risk of developing heart disease, but are unaware that they have hypertension," said Quynh Nguyen, a doctoral student at UNC's Gillings School of Global Public Health and the study's lead author. Hypertension is a strong risk factor for stroke and coronary heart disease, the leading cause of death for adults in the United States.The findings were published this week in the journal Epidemiology.Kathleen Mullan Harris, Add Health's principal investigator and a co-author of the paper, said the findings were noteworthy because they were from the first nationally representative, field- based study of blood pressure to focus on young adults."The message is clear," said Harris. "Young adults and the medical professionals they visit shouldn't assume they're not old enough to have high blood pressure. This is a condition that leads to chronic illness, premature death and costly medical treatment."
SAN FRANCISCO, March 29 (Xinhua) -- Computer networking equipment giant Cisco Systems Inc. on Tuesday announced the intent to buy privately-held software company newScale Inc., in a move to complement and expand its offerings in cloud computing.Based in San Mateo in the U.S. state of California, newScale provides software that delivers a service catalog and self-service portal for information technology (IT) organizations to select and quickly deploy cloud services within their businesses.Founded in 1999, the company now has more than two million users worldwide, including 20 percent of the Fortune 50 companies, according to information posted on newScale's website."With the acquisition of newScale, Cisco will be able to accelerate the deployment of cloud services through a service catalog and self-service portal that allows customers to easily manage their IT infrastructures," Parvesh Sethi, Cisco's senior vice president, noted in a statement.Cisco said it expects to close the deal in the second half of its fiscal year 2011, without disclosing financial terms.
LOS ANGELES, April 14 (Xinhua) -- Vegetarians experience a much lower risk of metabolic syndrome than non-vegetarians, U.S. researchers have found.Researchers at Loma Linda University in California based their findings on analysis of more than 700 adults randomly sampled from a long-term study of the lifestyle and health of almost 100,000 Seventh-day Adventist Christians across the United States and Canada.While 25 percent of vegetarians had metabolic syndrome, the number significantly rises to 37 percent for semi-vegetarians and 39 percent for non-vegetarians, according to the study published in the April issue of the journal Diabetes Care.The findings showed that the risk of developing metabolic syndrome is 36 percent lower among vegetarians than non- vegetarians.This means that vegetarians are less likely to develop heart disease, diabetes and stroke -- three major conditions that are closely linked with metabolic syndrome, the researchers say.The study also found that vegetarians, though slightly older than non-vegetarians, had lower triglycerides, glucose levels, blood pressure, waist circumference, and body mass index (BMI). Semi-vegetarians, meanwhile, also had a significantly lower BMI and waist circumference compared to those who ate meat more regularly.The findings will not be affected by other factors such as age, gender, race, physical activity, calories consumed, smoking, and alcohol intake, the researchers say."In view of the high rate of metabolic syndrome in the United States and its deleterious health effects, we wanted to examine lifestyle patterns that could be effective in the prevention and possible treatment of this disorder," says lead researcher Nico S. Rizzo, PhD."I was not sure if there would be a significant difference between vegetarians and non-vegetarians, and I was surprised by just how much the numbers contrast," he says. "It indicates that lifestyle factors such as diet can be important in the prevention of metabolic syndrome."