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When I was diagnosed, I kept wanting to talk to someone who had been through this before and had done well, Green said. "But it seemed like nobody had heard of this or had any connection with anyone who had this, and that's when I realized how incredibly rare it was."Ocular melanoma refers to a malignant tumor that develops from cells called melanocytes that produce the dark-colored pigment melanin, which is present in people's skin, eyes and hair and the lining of some internal organs, according to the Ocular Melanoma Foundation.Symptoms vary by person but generally include blurry vision, spots in the visual field and vision loss, according to Dr. Marlana Orloff, an oncologist at Jefferson University Hospitals in Philadelphia, who is treating a number of the people in the Alabama group."For the primary eye tumors, it will either be incidentally picked up on routine eye exam having no symptoms, or more commonly patients have symptoms of a retinal detachment with flashes and floaters or blurry vision," Orloff said.Ocular melanomas are the second most common type of melanoma -- after cutaneous, or skin, melanomas -- and represent about 5% of all melanoma cases. However, ocular melanomas behave much differently than cutaneous melanomas and are generally considered to be more lethal, according to Orloff."Even though people want to lump it in with skin melanoma, we know that it's a very different disease, and a lot of the treatments for skin melanoma don't work for eye melanoma. There's really nothing officially FDA-approved to treat eye melanoma," Orloff said.In about 50% of ocular melanoma cases, the cancer spreads, or metastasizes, to the liver. Only about 80% of patients with liver metastases survive longer than a year, according to a 2005 study.But Allyson Allred, a preschool teacher in Birmingham, has beaten those odds."My doctor said only 3% make it as long as I have. Ninety-six percent of the people die once it spreads to their liver, and mine spread to my liver in 2008," Allred said.Allred was diagnosed with ocular melanoma in 2001, at the age of 31, 11 years after she graduated from Auburn. She was the second person in her group of friends to be diagnosed with the condition, she says."I was the second one diagnosed from Auburn, and I'm the one who told my doctor in Philadelphia that I had two friends with the same cancer, and that's when they realized there may be a cluster in Auburn and started researching this," Allred said.Allred has undergone two liver resections and is receiving radiation to shrink metastatic tumors that have spread to at least nine places in her body, she said."The cancer in my liver is stable, but in December, it went to my adrenal glands, a place near my kidney, a place near my diaphragm and a place next to my thyroid. So I did radiation on all those four spots. And last week, I found out that it had gone to my brain, and began radiation on my brain," Allred said.There is no known cure for ocular melanoma, although radiation therapy and surgery can help prolong the length and quality of life, according to Orloff."Once they're diagnosed, the treatment is often radiation," Orloff said, "or if the tumors are very large or depending on location, enucleation, or removal of the eye," may be necessary.The exact cause of ocular melanoma is still unknown. Individuals at highest risk include those with light eye color, those with light skin color and those exposed to high levels of artificial UV radiation. People with certain occupations, such as cooks and metal workers, also appear to have an increased risk, according to a 2001 study.No common cause has been identified in the current group of cases, Orloff says."We are not calling them official clusters. In order to meet the definition of a 'cluster,' you need to look at the expected incidence and observed incidence, and for a number of reasons it's been hard to qualify these as true clusters," Orloff said."But certainly, it's a unique accumulation of cases," she added.The Alabama Department of Public Health indicates it is evaluating the recent increase in cases but says it has not identified a common source."We are working closely with Auburn, a survivor we have connected with and Dr. Orloff's team," said Justin George, director of cancer epidemiology at the Alabama Department of Public Health. "We are collaborating and working in an advisory role; the survivor who has spoken out is providing us a complete list of all those who have been sickened, and then we will work to verify the incidents and make sure the cases meet the definition of ocular melanoma."Auburn said in a statement that it is "working closely with the Alabama Department of Public Health, which is leading the review of area cases of uveal melanoma. Researchers from the Sidney Kimmel Cancer Center and the coordinator of research in North Carolina have also been involved."While we have been informed by ADPH officials that it would be premature to determine that a cancer cluster exists in the area, we are cooperating fully with their work. The health and safety of our students, employees and alumni are of the utmost importance."Allred believes the group of cases among former Auburn students is no coincidence. She and at least two other patients lived in neighboring sororities and were all education majors, she said.Green and another patient "were in the same sorority, and my sorority dorm was right next to theirs. And we were all education majors," Allred said."We need the funding for the research to figure out what possibly could be the environmental cause. ... There must be some link, and if we can find that link, we're that much closer to finding a cure and preventing people from continuing to get this," she added.Three of the physicians treating the Alabama cases have also organized a task force to help raise awareness and funding for research into the causes and treatments of ocular melanoma, according to Allred."Auburn has so far not contributed money, so we're going to go back and try to get some other options to get our funding," she said."But we've had lots of people praying for us, and I believe in the power of prayer," Allred added. "I have a strong faith that the Lord is my healer, and we have many hundreds of thousands of people praying who have gotten us through this." 6337

UPDATE: 1M+ customers out after 48 hours of restoration efforts. All substations and 1K+ main power lines restored. https://t.co/I4gg8ZPATu pic.twitter.com/X2Xv3FBNao— FPL Newsroom (@FPL_Newsroom) September 14, 2017 215

We are very saddened by the loss today, and our hearts and prayers go out to them, said Amy Bottegal, the President of the Stuart Air Show. "I've never had to experience something like this before, it's my first time, and it's very sad."Photos posted to social media by MCSO showed the aircraft on the grass at Witham Field with its wings smashed and metal debris scattered around it. 384

Washington is currently one of the hardest-hit states by COIVD-19. At least 109 people have died in the Seattle area alone. In Michigan, 60 people have died, and there are nearly 3,000 confirmed cases across the state.Amid reports that the United States had reached 100,000 confirmed cases of the coronavirus — the most in the world — Trump was asked about his presidential guidelines on social distancing, which expire on Monday. He declined to say if he would reinstate the guidelines this weekend but said he would speak to the task force before making a decision. Trump was also asked about his decision to invoke the Defense Production Act to order GM to begin producing ventilators to address a nationwide shortage. When asked about his comments on Thursday night, casting doubt on whether governors actually needed the number of ventilators they were asking for, Trump said he thought many governor's estimates were high, and he hoped he could provide and surplus ventilators to other countries. 1002

when he declined to endorse the US government's assessment that Russia interfered in the 2016 presidential election, saying instead that he believed Putin's denial that his government meddled. Trump has also dismissed credible allegations that Putin uses violence against his opponents, saying in 2015: "I haven't seen any evidence that he killed anybody, in terms of reporters."Putin added on Thursday: "This is just the continuation of the internal political battle, one party that lost the elections, the Democrats, and are now trying to find new ways by accusing Trump of collusion with Russia. But then it turns out there was no collusion, this can't be the basis for the impeachment. Now they came up with some pressure on Ukraine, I don't know what is the [pressure] but this is up to your congressmen."The question was asked by Dmitry Simes, head of the Washington-based think tank Center for the National Interest, mentioned in the Mueller report for providing advice to Trump's campaign on Russia.The two articles of impeachment passed against Trump charged him with abuse of power for withholding nearly 0 million in US military aid and a White House meeting while pressuring Ukraine's president to investigate a potential political rival, and obstruction of Congress for thwarting the House's investigative efforts. 1330