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Excessively high or low body mass index measurements have been linked to an increased risk of dying from nearly every major cause except transport accidents, new research says.The?study, published Wednesday in The Lancet Diabetes and Endocrinology and conducted by scientists at London School of Hygiene and Tropical Medicine, revealed that BMI that's either too high or too low is tied to increased morbidity from a range of major diseases.Krishnan Bhaskaran, lead author of the study and associate professor of statistical epidemiology, noted that his team found "important associations" between BMI and most causes of death."BMI is a key indicator of health. We know that BMI is linked to the risk of dying overall, but surprisingly little research has been conducted on the links to deaths from specific causes," he said."We have filled this knowledge gap to help researchers, patients and doctors better understand how underweight and excess weight might be associated with diseases such as cancer, respiratory disease and liver disease."BMI is determined by dividing a person's weight in kilograms by the square of their height in meters.The study authors say they discovered that maintaining a BMI in the range of 21 to 25 kg/m2 is linked to the lowest level of morbidity.BMI outside this range was shown to have a "J-shaped association" with nearly all causes of death, not solely the most prevalent diseases. This means BMIs both lower and higher than the optimal range lead to increased risk of morbidity.The study, which analyzed data from 3.6 million people and 367,512 deaths, showed that obesity, or BMI of 30 or more, was linked to an increased prevalence of two major causes of death: heart disease and cancer."BMI higher than 25, the upper end of healthy, is linked to most cancers, most cardiovascular diseases, respiratory disease, and liver and kidney conditions," Bhaskaran said.Obesity was shown to reduce life expectancy by 4.2 years in men and 3.5 years in women, and it can contribute to other chronic conditions including respiratory disease, liver disease and diabetes.The British Journal of Cancer reported in April that obesity is linked to 7.5% of cancers in UK women.The charity Cancer Research UK estimated that 23,000 women will deal with obesity-related cancers by 2035. Obesity will also become the most common cause of cancer in women by 2043 if trends continue.The study also revealed that being underweight is linked to a "surprising wide range of deaths," including dementia, Alzheimer's, cardiovascular disease and suicide.However, Bhaskaran noted that links between low BMI and causes of death were more "observative," as it was less clear whether low weight was the direct cause of illness or rather a marker of poor health more generally.He also acknowledged the limitations of the study, which included a lack of information on the diet or level of physical activity of the individuals involved and the impact these factors may have had on morbidity.He nevertheless noted that the findings reiterated the importance of maintaining a BMI within the 21 to 25 range. 3130

ESCONDIDO, Calif. (KGTV) - Residents of a small mobile home park across the street from the proposed Newland Sierra development, Measure B on the March ballot, say they fear a "yes" vote to approve the project could do irreparable damage to their community.Deer Springs Oaks is made up of 32 mobile homes off Deer Springs Road, directly across the street from the Newland Sierra site. That plan, if voters approve, would allow for around 2,100 new homes, along with open space and infrastructure changes. Residents of Deer Springs Oaks, funded by the nearby Golden Door Spa, have been making the case to voters that Measure B will make a bad traffic situation worse and create a dangerous trap in a wildfire zone. But they also worry that the project could have a more direct impact on their homes. The building of Newland Sierra would require the widening of Deer Springs Road, as well as changes to the nearby interchange with I-15. While Newland Sierra developers say these will not affect the mobile home park, the residents say they are not getting any guarantees from Newland Sierra, the County, or CalTrans."We don't know what they're going to do, how they're going to do it," said resident Georgeann Higgins. "They're so arrogant as to not inform us. These are our homes." Lawyers representing many of the residents obtained plans for some of the alternatives being considered by CalTrans. At least two would cause major changes to Deer Springs Oaks, including the possibility of residents losing property and a road being moved to go through the center of the complex."They impact the park big time," said resident Tony Eason. "They would destroy the park."A spokesperson from Newland Sierra told 10News that the maps being used by the residents are outdated. He sent 10News at statement: “This is just another desperate attempt by the Golden Door Spa and its army of lawyers to try to confuse and scare voters. This alternative was one of more than a dozen road improvement alternatives that was studied. It was ultimately rejected by CalTrans and is no longer an option. The real truth is that Measure B will create affordably priced homes for working families with open space, parks and trails - a better choice than the current General Plan that permits a two million square foot mega-commercial development, mansions and parking lots." Calls to CalTrans to check the accuracy of the claims made by both sides were unavailable to be returned because of the federal holiday. 2494

Epidiolex, the first cannabis-based medication approved by the US Food and Drug Administration, is now available by prescription in all 50 states.The twice-daily oral solution is approved for use in patients 2 and older to treat two types of epileptic syndromes: Dravet syndrome, a rare genetic dysfunction of the brain that begins in the first year of life, and Lennox-Gastaut syndrome, a form of epilepsy with multiple types of seizures that begins in early childhood, usually between ages 3 and 5."Because these patients have historically not responded well to available seizure medications, there has been a dire need for new therapies that aim to reduce the frequency and impact of seizures," said Justin Gover, CEO of GW Pharmaceuticals, the maker of Epidiolex, in a written statement. "We are committed to ensuring that these patients can access this novel cannabinoid medicine that has been thoroughly studied in clinical trials, manufactured to assure quality and consistency, and is eligible to be covered by insurance for appropriate patients." 1063

FALLBROOK, Calif. (KGTV) - An employee at St. Peter the Apostle Catholic Parish in Fallbrook has been suspended after allegations of sexually inappropriate dating app chats were revealed in a video released by a vigilante group that conducts stings to catch suspected predators. 10News is not revealing the name of the employee because he has not been charged with a crime.A spokesperson for the Roman Catholic Diocese of San Diego confirmed the employee's suspension, telling 10News the church pastor called the San Diego County Sheriff's Department to report the employee after seeing the video posted on social media Saturday morning.The video was captured Nov. 21 by a group calling itself the "CC Unit" -- "CC" stands for "Creep Catching." The group has posted more than 60 videos over the past year, including one that led to the court martial of a Camp Pendleton Marine.In an interview with 10News, the group's leader, who asked to be identified as "Ghost," said they create profiles on dating sites. When someone reaches out, the CC Unit decoy claims to be a minor. In this particular case, Ghost claimed to be 14. Ghost said the conversation turned sexual, with the employee asking for nude pictures and eventually a meet-up. When he arrived for the meeting at a grocery store, instead of a 14-year-old boy, he was confronted by several men who were recording on their phones. The video stretches for several minutes as the employee tries to evade the CC Unit. "He was denying we had his pictures, we had his chat logs," Ghost said. "I was like 'OK, if you're so afraid, if you don't know what's going on, why don't you call the police because that's what any normal human being would do?'"Ghost admits that law enforcement does not approve of his actions. Criminal defense attorney Guadalupe Valencia told 10News that vigilante groups make the job of law enforcement harder and can jeopardize criminal investigations and prosecutions. "They can cause this person to maybe go free of prosecution because they mishandled the situation. That's a really big danger," said Valencia. Valencia said the CC Unit members could be opening up themselves to criminal charges or civil liability.Despite the criticism, Ghost said he stands by his actions. "They say it makes it harder for them, but I haven't seen them do as much work as I have done over the past year. I think the slaps on the wrist they (sexual predators) get right now is nothing compared to the embarrassment they go through when I expose them," said Ghost. 2532

ESCONDIDO, Calif. (KGTV) - Escondido Police announced Saturday the arrest of a 13-year-old boy in a case involving Xanax overdoses at Rincon Middle School.Six children aged 11 to 13 years were found to have taken the anti-anxiety drug at lunch time on October 25.Three of the children required emergency medical treatment.  All six have since recovered with no lasting effects.RELATED: Juveniles hospitalized after taking XanaxEscondido Police arrested the juvenile suspect Monday after an investigation. The boy is charged with selling or distributing narcotics or illegal substances. He is in the custody of his parents. 635