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GAITHERSBURG, Md. -- Under the fluorescent lights, inside a series of labs, researchers believe they may have cracked the code to create a vaccine for the new coronavirus, which has officially named COVID-19.“It’s rapidly evolving,” said Dr. Gregory Glenn, president of research and development at the Maryland-based company Novavax. “As a company, we are very invested in looking at how to protect people against infectious diseases.”Novavax is one of several pharmaceutical companies around the world, racing to develop a vaccine for the strain of the coronavirus, which recently emerged in Wuhan, China.“We have to puzzle-solve with vaccines,” Dr. Glenn said. “We think about: what do we want to have the immune response to target? Because that should block the infection and stop the illness and that’s the goal here.”He showed a three-dimensional computerized depiction of what the virus looks like.“The coronavirus – corona being ‘crown’ – has spikes,” he said. “Those spikes have a very important function. They let the virus bind to the human cell and then those spikes act as a syringe to inject genetic material into the human cell.”A vaccine would potentially stop that process, thereby protecting a person from the coronavirus.“We have the gene, we have the vaccine, we’re going to move it into animal testing shortly,” Dr. Glenn said. “Our goal is in late spring to be testing in humans.”It normally takes about 18 months to get human trials started on a vaccine. This shorter time frame is nothing new for the company; they developed an Ebola vaccine within 90 days ready for testing – but there’s a catch.It can take years for a vaccine to get approved, but under dire circumstances sometimes they can be used through something called “expanded access” or “compassionate use” – meaning, the vaccine can be used in humans, before it’s fully licensed.“That happened with Ebola – they didn’t have a licensed vaccine, but they were able to use it under ‘compassionate use,’ they developed evidence that it was working,” Dr. Glenn said.As for a fully approved coronavirus vaccine, experts say that would take longer.“A vaccine in a year would be record-setting time, but not in time to probably have much impact for this disease outbreak,” said Dr. Eric Toner with the Johns Hopkins Center for Health Security.However, if the coronavirus sticks around or comes back stronger in a second wave of the disease, Dr. Glenn said they want to be ready.“We know time is of the essence here,” he said.So far, approximately 73,000 people have been infected and more than 1,800 people have died from the most recent strain of the coronavirus. 2653
Hurricane-force winds and heavy rains ripped through the British and US Virgin Islands as Dorian neared Puerto Rico Wednesday afternoon.Dorian's wind speeds won't approach those of Maria, the 204

Hours before dying in Fiji, Michelle Paul texted her parents saying she had been vomiting for hours during her vacation."We are both going to the doctor now. We have been throwing up for 8 hours. Dave has diarrhea. My hands are numb. We will text when we can," she told her father, Marc Calanog, on a WhatsApp message.Paul and her husband, David, became ill while vacationing in Fiji late last month and died within days of each other. The deaths of the Texas couple are being investigated by health officials on the South Pacific Island, with help from the US Centers for Disease Control and Prevention."We just got back from the clinic. They gave us fluids and an anti-nausea drip," Calanog said his daughter said on another message. "They gave us electrolyte packets and anti-nausea pills. We still don't feel 100%. Going to rest in our room."But their illnesses quickly worsened.After his daughter died, Calanog said he urged his son-in-law to focus on taking care of himself because Michelle was already in a better place. He died two days later.Calanog said they are still unsure what happened to his daughter and son-in-law and that he and his family are concentrating on taking care of his 2-year-old grandson.Fiji's Ministry of Health said investigations into the cause of death are ongoing. It said influenza has been ruled out. Tissue samples are en route to the CDC's Atlanta headquarters for testing."And at this stage we do not believe there is any risk to the public. It would be premature to speculate further on the cause of death until the investigation is complete," the ministry said.,The deaths were confirmed by a US State Department official, who said in a statement that American authorities were "closely monitoring" the investigation.The Fijian ministry said it is also working with the country's police forensics department and the World Health Organization to determine the cause of death.The couple died over Memorial Day weekend, the Fort Worth Star-Telegram reported. Their families are currently working with US officials to repatriate their remains. 2094
Homeowners in the Merrimack Valley region of Massachusetts continue construction on their homes after over-pressured gas lines ruptured last September, killing a man and destroying five homes. More than 130 additional homes were damaged.“It was frightening because you are hearing one here and you hear there’s explosions in Lawrence, there’s explosions in Andover, there’s another house over here,” says North Andover resident Rosemary Smedile.Smedile let our 360-degree camera inside. Take a virtual tour of the damage beginning in her basement below. Use your mouse to navigate the home. Hover over any of the colored circles to learn more about the area. 670
Flu activity remains high across the nation, and there's a second wave of severe infections striking some states.There were as many as 147
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