济南什么办法龟头敏感(济南包皮水肿图片) (今日更新中)

Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

EL CAJON, Calif. (KGTV) -- Police are investigating after a car slammed into an El Cajon power pole Tuesday afternoon, leaving some residents without power.The crash happened on Madison Avenue and 3rd Street near Madison Avenue Elementary School."It was just kind of like a loud boom," said Julia Jorgensen, who heard the crash.  "The car was smoking at the front for a little bit, so I was really scared that it was going to blow up."According to police in El Cajon, the crash caused extensive damage.  In photos from the scene, the power pole appears to be split in half. SDG&E turned off power approximately 120 residents in the area as a precaution.  Power was restored for most residents by 4:30 p.m.The crash also closed Madison Avenue between 3rd Street and Macon Street, creating traffic as parents picked up their children from one of several schools in the area.Police say the incident is being investigated as a DUI crash. A witness described the driver as stumbling out of the vehicle shortly after the crash."I ran up to him.  I said, 'Who was in the car, like who's in there?' and he was really really out of it.  His eyes were rolling in the back of his head," Jorgensen said. "He was kind of falling everywhere.  He was really really sweaty.At one point, she says he even laid down in the grass, curled up like a ball.Both the driver and passenger were responsive but taken to the hospital with serious injuries. SDGE expects to reopen the street by 10 p.m. 1540

EL CAJON, Calif. (KGTV) - A renowned El Cajon artist who captured a moment in American history is helping it live on today. Olaf Wieghorst, known as the dean of Western art, spent most of his adult life in El Cajon. “He couldn't not paint and everything he painted had a cowboy, an Indian or a horse in it,” said Jim Daniels of the Olaf Wieghorst Museum. Daniels said horses were in Wieghorst’s blood. “Great horseman having been around horses his whole life,” said Daniels. Complete Coverage: Life in El CajonWieghorst’s father was a photographer who taught his son how to do handstands on stools and on horses. Wieghorst used his horse skills as a mounted patrolman in the New York Police Department. After he married a woman named Mae, he was motivated to leave the East Coast. “He was not enamored with her mother so he got out a map of the United States and wanted to find the place farthest from New York,” said Daniels. In 1945, Wieghorst started a new life in El Cajon as a natural artist with no formal training. “He traveled in a pickup truck with a camper shell on it and spent time with Navajo and local Indians all through the west,” Daniels said. Wieghorst often painted from a room which still shows paint splatters on the wall. As his reputation grew, so did his fans: Presidents Eisenhower, Ford, and Reagan, and celebrities including Burt Reynolds and Clint Eastwood. The painter also appeared in western movies with John Wayne, including “El Dorado” in 1967. “They became good friends and drinking buddies and John Wayne would come down and hang out with him.” Two of Wieghorst’s paintings, the Navajo Madonna and Navajo Man sold for more than million in 1985. However, interest in Wieghorst’s work has waned. “I think there's a lot of people around El Cajon still who've never heard the name and could care less, and there were a lot of people then who had no idea they had one of the greatest artists the world has ever had,” said Daniels. The Wieghorst Museum brings in children to keep the painter’s legacy alive. “Part of the strength of a community is remembrance of the past and appreciation of greatness and that's displayed through art.” Wieghorst died in 1988 at the age of 88. 2217

Do you want to hit the road for a weekend trip or summer vacation? As states begin opening up, many are planning an escape. But there are some things you should you know before you make the trek.Vacations were canceled, trips delayed, destinations rescheduled amid the spread of the coronavirus pandemic. As America starts to think about traveling again, AAA wants to help you plan ahead.AAA spokeswoman Jeanette Casselano said, “We always do our research before we hit the road but now people are asking lots of questions about what’s open, what can I do, what activities are free to me when I go to a certain place.”Now, there's a new tool to help you while on the go. Trip Tik is an interactive road map, and it gives you everything you need to know before you leave home."Dining solutions or dining restrictions in place, face covers if they’re required, national lands or parks are open,” Casselano said.Trip Tik provides updated information for all 50 states. In certain areas of New Mexico, for instance, only tribal members are allowed. In South Dakota, you'll have to fill out a health questionnaire. Upon entering Florida, you'll have to fill out a traveler form. All things you need to know."That’s important information to take into account when you’re traveling,” Casselano said. “COVID has hit every part of the country and you need to understand what’s happening in that locality that you’re traveling to make the best decision.”The map points out hot spots, and number of cases by state and county. So you can make an informed decision about where you're going and where you'll be staying. The interactive map has gotten a lot of web traffic as people start feeling comfortable leaving home.And as you start planning - there's some things you should think about and discuss with your family:-Know where the rest stops are, whether they're open, and whether you'll be comfortable stopping.-Figure out whether restaurants are open, and pack extra food in case of closures.-You'll want an emergency roadside kit.-You'll need a mask, gloves, disinfectant, cleaning supplies for yourself, your family and your car.AAA also recommends making sure your car is in good shape. They've been fielding a lot of dead battery calls from cars that haven't moved during lockdown.“We had a lot of people who weren’t traveling, everyone working from home,” Casselano said. “You have to take care of your cars when that happens so we provided a lot of information and tips to keep your car and battery healthy.”Check on your car, and check your own health before you leave your hometown. 2592

EL CAJON, Calif. (KGTV)- 10News took a trip around El Cajon to visit some of the spots most cherished by locals.The first stop was Summers Past Farms, right off Olde Highway 80. Here you can find a calm place to enjoy a freshly brewed cup of coffee and beautiful gardens."We get people from all over," said Owner Sheryl Lozier. "We together built the post-and-timber barn, planted all the gardens and we opened our gates to the community in 1992."Lozier and her husband Marshall made it their mission to provide perfect gardens, free of charge, for the whole family to enjoy.COMPLETE COVERAGE: Life in El Cajon"Your inspiration to come out and visit would actually be to get some fresh air and to unwind and relax," she said.The couple lives on the property in a 1940s cottage. They transformed their garage into their very own homemade herbal soap shop. They also have a gift shop on the site. "It's just filled with everything you'd like to get for your mom, your sister, your best friend," said Lozier. "You’re right here in your community shopping local."From birthdays to weddings, they host it all."Stay a while, just come and see what we’re doing at Summers Past Farms," said Lozier.For the next stop, we didn't have to travel far. Right across the street from Summers Past Farms, you'll find Friends of Cats."I always tell people go across the street to Summers Past, then when you've had some coffee and donuts come see us," said Terry Hogan, a Friends of Cats volunteer for 30 years.RELATED: El Cajon's rich history dates to Gold Rush daysThe no-kill shelter was founded in 1929. Hogan said the cats are all relinquished by their owners. Approximately 70 cats of the 240 are up for adoption."Sit in the chair, sit on the floor, let the cat pick you," said Hogan. "The older cats are dollars, the cats under eight, up to about a year, those are dollars. And the kittens are 0 dollars."The cats are microchipped, spayed and neutered before they leave the shelter. They also come with a free ten-day vet visit.Or, you can simply come by and hang out with the curious cats, without making any commitments."The cozy cottage, this is where the lifetime care cats are," said Hogan as we took a tour of the facility. "We maintain these cats for life for people when they pass." Next up was Marechiaro's Italian Restaraunt also on Olde Highway 80.This family owned restaurant has been satisfying hungry customers for 64 years, 46 of those years in El Cajon."Making pizza is like riding a bike," said Owner Joe Brunetto. "You never forget how to do it.""We got great food, we got a great reputation and we care about you," he said.Brunetto took over his father's restaurant and he's keeping it in the family."My daughter's taken over now," he said.RELATED: Life in El Cajon: City takes risks to help lower cost of housing"It's really important that it stays in the family," said daughter Anna Brunetto James. "It is kind of a local secret spot."Brunetto James has been the general manager for about a year."My goal here is 50 percent of making sure our customers are well taken care of so they feel like home," she said. "The other half is making sure my staff is happy and enjoy working here, because if they’re happy then our customers will be happy."Marechiaro's has a full list of Italian entrees to choose from. But, the most popular item is the pizza."The pizzas the way we make them now, is the same way 60 years ago," said Brunetto James. "I think that's really cool."If you're craving some barbecue, make your way over to the Wrangler Family Barbecue on El Cajon Blvd. The meats are slow cooked for 18 hours. The most popular item is the combo plate which includes beef, ham and spare ribs.Owner JR Henderson has a real success story."I was here washing dishes, I start managing, then I bought the store," he said. That was in 2001."When I bought the store, I was scared, but I knew what I was doing," said Henderson.Decades later, he's still doing it all."There's nothing I don't do," he said. "I wash dishes, I bus tables, I clean, I mop."These are just four of the hidden gems, adding to life in El Cajon. 4140

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