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Pfizer announced Monday that its COVID-19 vaccine candidate has been 90% effective.In a press release, the company said that in Phase 3 trials, the vaccine has proven to promote a vaccine efficacy rate above 90% following the two-shot regimen.The Associated Press said that while Pfizer's announcement means the company is on track to file an application for emergency use authorization later this month, it does not mean a vaccine is "imminent" and more studies are needed.Pfizer's vaccine candidate began Phase 3 testing in the summer and is among a handful of vaccine candidates that could be distributed in the coming months pending FDA approval.Phase 3 trials consist of testing about 30,000 voluntary participants in a double-blind study — meaning half of those participating receive the vaccine, and half receive a placebo. Pfizer's vaccine requires two shots, which need to be taken 28 days apart.According to Pfizer, 90% of those who were tested for the vaccine had developed protection against the virus seven days following the second shot.Pfizer is already in the process of producing millions of doses of its vaccine candidate after the U.S. government agreed to pay .95 billion for 100 million doses of the vaccine, should it prove effective. If and when the FDA grants approval for the vaccine, it will be distributed to hospitals around the country by the U.S. military in an effort the Trump administration has dubbed "Operation Warp Speed.Even though hundreds of thousands of doses of the Pfizer vaccine will be ready for shipment if it is approved for emergency use, it will need to be rationed in the first months of its availability. According to a playbook for "Operation Warp Speed," essential health care workers and people in high-risk populations would have the first opportunity to get a COVID-19 vaccine. The rest of the general public will be able to get the vaccine as more doses become available later in 2021.Pfizer was one of a handful of companies that pledged in September not to distribute their vaccine under political pressure, and would only do so if it proved to be effective in large scale trials.Monday's announcement sent stock market futures through the roof, as investors eyed a return to economic normalcy should Pfizer's vaccine be given emergency approval in the coming days or weeks.President Donald Trump also celebrated the announcement in a tweet on Monday morning."STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!" Trump tweeted. 2524

PHILADELPHIA – A Scottish Deerhound named Claire was named Best in Show at the National Dog Show on Thursday.Claire won top prize at the annual Thanksgiving Day event after winning in the hound group and dazzling the judges.During the NBC broadcast, commentator David Frei said the dog was doing exactly what it was bred to do."It was built perfectly, has an active, easy gait, and is elegant in the way that Sir Walter Scott had in mind when he called the Deerhound the most perfect creature," said Frei.So Pure ??The Scottish Deerhound is the Best in Show at the #NationalDogShow pic.twitter.com/M45ein5v4G— NBC Sports (@NBCSports) November 26, 2020 Like many events this year, the dog show was held without spectators to prevent the spread of the coronavirus.In recent years, The Kennel Club of Philadelphia has conducted two separate dog shows, but this year, the club only conducted one show that was divided over two days, on Nov. 14 and 15.The competition was also limited to some 600 dogs, a decrease of 70% from the near 2,000 entries usually on hand.Tomorrow on TODAY: Meet this year’s #NationalDogShow 2020 Best in Show winner: Claire the Scottish Deerhound! @NBCSports @NBC pic.twitter.com/RXoKPWarGb— TODAY (@TODAYshow) November 26, 2020 1259

Our personality affects the decisions we make, including how we shop. And as we know, Black Friday is going to be different this year. Those changes, along with having certain types of personalities, may not help our wallets.Being impulsive can lead people to make quick decisions and buy things without really thinking about it. And now that a lot of these Black Friday deals are online, it can trigger that impulsiveness, partly because we're not physically handing money over to someone.“When there’s no cash involved and there’s no real exchange like that, it’s just kind of like this single swipe, that really makes it a lot of harder to engage that part of our brain that help us make that decision in the best way for us,” said Dr. Michael Vilensky, a psychologist at Ohio State University’s Wexler Medical Center.The stress we're all feeling this year can also be a trigger. You might have family members who are sick, maybe you lost your job, and maybe you're stressed just because you haven't seen your family in a while and won't be able to during the holidays.Psychologists say we may resort to shopping to feel like we have some kind of control.“If it does feel like shopping is a way to manage difficult emotions, think of some other strategies that may be a way to do that. If it’s talking to a friend. If it’s doing some other kind of relaxing activities or stress reduction activities,” said Vilensky.In addition to this, one thing we can do to control our shopping is getting rid of apps that have a single swipe or single tap payment option.If you know you'll be shopping online, give yourself 24 hours to think about a purchase before you pay for it. That'll help you think about whether you really need or want it. 1743

Perhaps we'll finally find out who the boss is.Tony Danza and Alyssa Milano confirm a reboot of "Who's the Boss?" is in the works.The original sitcom ran on ABC from 1984 to 1992.It starred Danza as single father Tony Micelli, who goes from being a professional baseball player to a live-in housekeeper for advertising exec Angela Bower, who was played by Judith Light.Milano starred as his daughter, Samantha.Danza and Milano shared news of the show's return on social media. 484

PEORIA —UPDATE: 10News spoke with Martha Thy's landlord who said she was a loving aunt, sister and daughter. He said he's known the family for 10 years and they are hard workers. He said they were planning on moving to Arizona to be closer to her sister who recently bought a house there.Thy will be brought back to California to be laid to rest.The landlord said he had met Fernando Acosta before, saying he was her boyfriend, and he was a normal guy. He said Acosta had spent some time in jail, but that has not been confirmed by authorities.---------------------A 25-year-old Arizona man who was driving a San Diego-area woman's car is accused of fatally stabbing her after the vehicle veered off a freeway and crashed Friday morning.Fernando Acosta of Phoenix got out of the car and accosted a witness with a knife before repeatedly stabbing Martha Thy of Spring Valley, California, along the Loop 101 freeway in Peoria, according to an Arizona Department of Public Safety probable-cause statement released Saturday.Thy was stabbed while she was still inside the white Lexus sedan and then while on her knees on the ground outside it after she crawled out and closed a door behind her. Acosta initially was in the driver's seat when he began stabbing Thy, who was seated in the passenger seat, the statement said.He then got out of the driver's side of the vehicle, going around to the passenger's side and resuming stabbing Thy before returning to the driver's side when she attempted to get away, the statement said.Thy died at a hospital. The statement said she was stabbed or cut at least 20 times.Several bystanders got out of their vehicles and tried to stop Acosta from attacking the woman.Gustavo Mu?oz was one of those bystanders. When he saw the crash, he immediately pulled over and jumped out of his car to help.“I ran towards the vehicle, and when I got to the other side of the ditch the man comes out with a knife. Hands full of blood. [His] face, body was filled with blood,” said Mu?oz.Mu?oz says he yelled for other drivers who stopped to help.“The guys that were there, they got their gun so we could try to scare him,” Mu?oz said. "One man fired shots at the ground to see if he would drop the knife and stop stabbing the lady that was in the vehicle.”Mu?oz told ABC15 that eventually one man ran and tackled the suspect and knocked the knife from his hands. Mu?oz and others piled on and held the man down until law enforcement arrived."People everywhere, some screaming, yelling going on, so you can only imagine what an officer's feeling when he arrives on scene and all he sees are people running around," Trooper Kameron Lee said.Acosta remained jailed Saturday on suspicion of premeditated first-degree murder and aggravated assault.The statement did not mention a possible motive. No additional information was available, the Department of Public Safety said Saturday.Loop 101 Agua Fria northbound was closed from Peoria to Thunderbird roads for several hours due to the police investigation. The roadway was reopened around 4 p.m. 3070

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