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WASHINGTON, July 18 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) on Monday commemorated the 90th birthday of astronaut John Glenn, the first U.S. astronaut to orbit the Earth and also the oldest person to fly to space when he launched on the space shuttle in 1998."John Glenn is a legend, and NASA sends him our best wishes on this major personal milestone," NASA Administrator Charles Bolden said in a statement. "John's legacy and contributions to the continued progress of human spaceflight are immense. His example is one we continue to emulate as we push toward farther destinations in the solar system."After a distinguished flying career with the Marines in World War II and Korea, Glenn joined NASA in 1959 as one of the country' s first astronauts in Project Mercury. On Feb. 20, 1962, Glenn piloted the Mercury-Atlas 6 "Friendship 7" spacecraft on the first U.S. manned orbital mission. He launched from NASA's Kennedy Space Center in Florida to successfully complete three orbits of the Earth.Glenn flew to space again on the STS-95 mission in 1998 aboard the space shuttle Discovery. As a mission specialist, Glenn supported deployment of a variety of research payloads and participated in investigations about spaceflight and the aging process.
LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.
SAN FRANCISCO, June 1 (Xinhua) -- Microsoft on Wednesday gave a preview of its next-generation operating system code-named "Windows 8."The software giant introduced the successor to Windows 7 at the ninth edition of The Wall Street Journal's Digital: All Things Digital in Rancho Palos Verdes, California, some 48 km south of Los Angeles.With an interface quite different from legacy Windows, Windows 8 looks more like Windows Phone 7 and features an app management from Windows mobile operating system. It is the first major attempt by Microsoft to expand a mobile operating system to desktop status, and is expected to be touch-friendly and work seamlessly on desktops, laptops and tablet computers.For legacy Windows users, they need to swipe up from the bottom of the screen to get to the Windows 7-based view. Microsoft said the new system will be compatible with all Windows 7 logo PCs, software and peripherals.During the demonstration, Steven Sinofsky, Microsoft's head of Windows, also said the importance of not abandoning the established technologies from the traditional PC. "The mouse and the keyboard aren't evil. They're just tools. There are a number of applications that require the greater precision offered by the mouse." said Sinofsky.Sinofsky did not say when Windows 8 would be available.Although there are some tablets running Microsoft's current Windows 7 operating system, the software giant has been criticized for failing to adequately respond to the fast growth of tablet computers, like Apple's iPad.
UNITED NATIONS, June 9 (Xinhua) -- Partners from UN agencies and governments, as well as civil society and the private sector gathered here Thursday to launch "Countdown to Zero: Global plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive.""Governments and foundations that support this plan are saying: we treasure all life equally," said UN Secretary-General Ban Ki- moon, who spoke at the event. "We give all people the best possible chance. We provide health care to all who need it."This new plan, which was formulated by a Global Task Team of more than 30 governments and 50 international and national organizations, aims to bring the number of new HIV infections in children to zero by the middle of the decade and help their mothers survive.The launch of Countdown to Zero came on the sidelines of the UN High-Level Meeting on AIDS, which runs from June 8-10, and has been an opportunity for participants to take stock of gains made in combating the disease and to agree on a declaration that will direct the actions of member states to prevent and treat HIV/AIDS over the next five years.Ban told the audience at the launch that history has proven that it is possible to make great strides in fighting HIV/AIDS, with the right amount of effort and coordination."Let us not forget that some regions have nearly achieved no new infections from mother to child," he said. "If we push hard, as we have committed today, with your continued help and with the will to do what is right for the world, we can spread this success to mothers everywhere."According to the Joint UN Program on HIV/AIDS (UNAIDS), the rate of HIV/AIDS transmission from mother to child was been reduced by 26 percent from 2001 to 2009.Former U.S. President Bill Clinton, who spoke at the launch, said that he believes the time to eliminate HIV/AIDS in children is at hand."We are here because we all recognize that the time has finally come to end pediatric AIDS worldwide and we believe we can do it," he said. "We know we have the capacity to produce the medicine, we know that."Clinton emphasized the fact that HIV/AIDS is often prevalent in less developed countries. Sub-Saharan Africa remains the region that has the most HIV/AIDS infected people."There are still too many kids who are born HIV-positive," he said. "Just 22 countries account for 90 percent of those pediatric infections."He said that there are not only moral reasons for wealthier countries to help these nations by investing in their HIV/AIDS responses, but that by doing so they increase their soft power -- influence that utilizes non-coercive measures."I think its important in a world where no one wants to look weak and the military justifiably has a claim on all of our budgets, we not forget that what my secretary-of-state often refers to as soft power issues, they have a bigger impact on our long term security," Clinton said. "I think that accounts in no small measure for the presence of leaders of global corporations here at this meeting today, they know this as well."Collaboration and close coordination of responses to HIV/AIDS, Clinton said, is also essential."There are still too many places where HIV and maternal and child health groups work completely separately," he said. "That dramatically reduces the likelihood that mothers are their babies will receive the full range of care. We simply have to all work together, both within governments and all of those who are trying to help to ensure that mothers get the drugs they should and that their babies are born without the virus."Clinton said that Goodluck Jonathan, president of Nigeria, who gave a statement at the launch as well, is an excellent example of the "strong political leadership and personal commitment" necessary to defeat HIV/AIDS and reach to goals set by the Countdown to Zero plan.In his speech, Jonathan said that Africa is has banded together through the Abuja Declaration, adopted in 2001, which turned attention and resources towards public health problems on the continent, particularly HIV/AIDS."That declaration was to make African countries spend at least 15 percent of their budget on their health sector and a reasonable percentage of this would be geared towards HIV prevention and control," he said.Budgeting shortfalls for fighting HIV/AIDS in Africa must be accounted for, Jonathan said, as African countries must not rely solely on donors to fund their responses."I intend to explore in the coming months in collaboration with colleagues in sub-Saharan Africa an effective and creative funding mechanism to ensure ownership and long terms sustainability of the HIV and AIDS response in Africa," he said.
SYDNEY, Aug. 25 (Xinhua) -- An Australian national survey has shown most respondents have been unsatisfied with their employers and managers on supporting employees with mental illness in the workplace, the charity Sane Australia said on Thursday.The survey, Australia's Working life and mental illness, by the national mental health charity Sane Australia, found that 95 percent of the 520 respondents thought employers and managers needed education on mental illness and how to manage its effects in the workplace.While more than 60 percent said their mental illness had not been a barrier when finding a job, the majority said that they haven't got any support from their employers or mangers once they were at work."The survey paints a concerning and unsatisfactory picture of Australian workplaces," SANE Australia's Executive Director Barbara Hocking said in a statement on Thursday."Many employees, including those who care for a family member with a mental illness, are being disadvantaged by a lack of flexibility, such as being able to work part-time, to work from home at times or to have adjustments made in the workplace," she said.According to the survey, two thirds of people reported to have revealed their histories of mental illness to their employer or manager.