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FALMOUTH, Kentucky — How you do find evidence of a 40-year-old murder? In pieces, mostly, according to Towson University associate clinical professor Dana Kollmann: Fragments of bone and enamel, rusted buttons and zippers, the rubber sole of a rotten shoe. Kollmann, a group of her criminal justice students and dozens of other volunteers spent the afternoon waving metal detectors and sifting through the topsoil at Kincaid Lake Park in search of these small tokens of 17-year-old Randy Sellers’s existence. Some were fresh off conversations with his family, where his parents passed around a picture of the smiling, dark-haired teenager and cried.“Not one of these students out here is getting a college credit,” Kollmann said. “They’re getting nothing but experience for this. They’re out here because they want to be here. They want to find Randy Sellers.”Sellers disappeared Aug. 16, 1980, according to police. Officers found him drinking at the Kenton County Fairgrounds that day and gave him a ride most of the way home. He vanished between there and the front door. Jack Isles, who identified himself Monday as a friend of Sellers's and claimed to have also been at the fairgrounds that day, said he often thought back to that night and regretted not driving Sellers home himself."I wish I could have told him to come on home," he said. "Let him go with me. I wish he was here, God-honest truth with you."Fourteen years later, serial murderer Donald Evans would confess to killing Sellers and burying his body at Kincaid Lake State Park — a killing in line with his self-described modus operandi, which involved preying on people at rest areas and parks. He drew a map leading investigators to the burial site.When they arrived and dug, however, they found nothing. The map was a lie or the work of a bad memory.It would take another three decades, Kenton County police Capt. Alan Johnson said Monday, for them to realize they might have misinterpreted Evans's drawing. “The park ranger here reviewed the case not too long ago,” he said. “They determined there was a possibility that the suspect may have held the map upside down.”Monday’s search was based on a new interpretation of the map, which Johnson hopes will finally unearth Sellers’s remains and allow his parents the relief for which they’ve waited most of their lives.“Any lead we get, it’s our obligation to investigate it to the fullest to bring closure to the family,” he said, adding later: “We’ve stayed in close contact (with his parents) through the whole process. They’ve been very appreciative and expressed a great deal of gratitude for the efforts going on.”According to Kollmann, any makeshift grave in Kincaid Lake State Park would have to be shallow. Anyone who dug further than two feet down would hit limestone.The clues, then, must have stayed in the top layer of soil or become tangled in the roots of trees as animals and weather shifted the landscape. That's if they’re really there.She and her students hope they are, she said.“It’s easy to become robotic in the field and to emotionally remove yourself,” she said. “I think you have to have that connection that we’re looking for people. People still missing after all this time.” 3234

First came a high fever, drenching sweats and muscle aches. Then, almost a month later, a weird numbness that spread down the right side of her body.Darlene Gildersleeve thought she had recovered from COVID-19. Doctors said she just needed rest. And for several days, no one suspected her worsening symptoms were related — until a May 4 video call, when her physician heard her slurred speech and consulted a specialist.“You’ve had two strokes,” a neurologist told her at the hospital. The Hopkinton, New Hampshire, mother of three is only 43.Blood clots that can cause strokes, heart attacks and dangerous blockages in the legs and lungs are increasingly being found in COVID-19 patients, including some children. Even tiny clots that can damage tissue throughout the body have been seen in hospitalized patients and in autopsies, confounding doctors’ understanding of what was once considered mainly a respiratory infection.“I have to be humble and say I don’t know what’s going on there, but boy we need to find that out because unless you know what the pathogenic (disease-causing) mechanism is, it’s going to be tough to do intervention,” Dr. Anthony Fauci, the nation’s top infectious disease expert, remarked during a medical journal interview last month.Doctors and scientists at dozens of hospitals and universities around the globe are seeking answers while trying to measure virus patients’ risks for clots and testing drugs to treat or prevent them.Gildersleeve said health authorities “need to put out an urgent warning about strokes” and coronavirus. Not knowing the possible link “made me doubt myself” when symptoms appeared, she said.Some conditions that make some COVID-19 patients vulnerable to severe complications, including obesity and diabetes, can increase clot risks. But many authorities believe how the virus attacks and the way the body responds both play a role.“COVID-19 is the most thrombotic (clot-producing) disease we’ve ever seen in our lifetime,” said Dr. Alex Spyropoulos, a clot specialist and professor at Feinstein Institutes for Medical Research in Manhasset, New York.Clotting has been seen in other coronavirus infections, including SARS, but on a much smaller scale, he said.Scientists believe the coronavirus enters the body through enzyme-receptors found throughout the body, including in cells lining the inside of blood vessels. Some theorize that it may promote clotting by somehow injuring those vessels as it spreads. That injury may cause a severe immune response as the body tries to fight the infection, resulting in inflammation that may also damage vessels and promote clotting, said Dr. Valentin Fuster, director of Mount Sinai Heart hospital in New York.It’s unclear how many COVID-19 patients develop clots. Studies from China, Europe and the United States suggest rates ranging from 3% to 70% of hospitalized COVID-19 patients; more rigorous research is needed to determine the true prevalence, the National Institutes of Health says.Prevalence in patients with mild disease is unknown and the agency says there isn’t enough evidence to recommend routine clot screening for all virus patients without clotting symptoms, which may include swelling, pain or reddish discoloring in an arm or leg.Some hospitals have found 40% of deaths in COVID-19 patients are from blood clots. Spyropoulos said that’s been true at his 23-hospital system in the New York City area, Northwell Health, which has treated over 11,000 COVID-19 patients.Cases there have dropped by almost half in the past month, allowing more time for research before an expected second and maybe third wave of infections, he said, adding: “We’re racing against time to answer the key clinical questions.”Patients hospitalized with any severe illness face increased risks for clots, partly from being bedridden and inactive. They commonly receive blood-thinning drugs for prevention. Some doctors are trying higher-than-usual doses for prevention in hospitalized coronavirus patients.A few have used powerful clot-busting medicines typically used to treat strokes, with mixed results. In guidance issued May 12, the NIH said more research is needed to show whether that approach has any benefits.Fuster was involved in preliminary research on nearly 2,800 COVID-19 patients at five hospitals in the Mount Sinai system. A look at their outcomes suggests slightly better survival chances for virus patients on ventilators who received blood thinners than among those who didn’t. Although the results are not conclusive, all COVID-19 patients at Mount Sinai receive blood thinners for clot prevention unless they are at risk for bleeding, a potential side effect, Fuster said.Some COVID-19 patients, like Gildersleeve, develop dangerous clots when their infections seem to have subsided, Spyropoulos said. Patients treated at Northwell for severe disease are sent home with a once-a-day blood thinner and a soon to be published study will detail their experiences. Spyropoulos has been a paid consultant to Janssen Pharmaceuticals, makers of Xarelto, the drug’s brand name.In addition, Northwell is taking part in a multi-center study that will test using blood thinners for clot prevention in COVID-19 patients not sick enough to require hospitalization.In a small study published May 15, University of Colorado doctors found that combined scores on two tests measuring clotting markers in the blood can help determine which patients will develop large dangerous clots. One test measures a protein fragment called D-dimer, a remnant of dissolved clots. High levels sometimes indicate dangerous clots that form deep in leg veins and travel to the lungs or other organs.Dr. Behnood Bikdeli of Columbia University’s Irving Medical Center, said D-dimer levels in many of his COVID-19 patients have been alarmingly high, as much as 50 times higher than normal.Concerns about blood clots in COVID-19 patients prompted a recent 30-page consensus statement from an international group of physicians and researchers. Bikdeli is the lead author.It says that testing to find clots that require treatment includes X-rays or ultrasound exams, but poses a risk for health care workers because the virus is so contagious. Bikdeli said he fears when protective gear was more scarce, some dangerous clots were undiagnosed and untreated.Social distancing may make people more sedentary and more vulnerable to clots, particularly older adults, so doctors should encourage activity or exercises that can be done in the home as a preventive measure, the statement says.Warnell Vega got that advice after collapsing at home April 19 from a large clot blocking a lung artery. Doctors at Mount Sinai Morningside think it was coronavirus-related. Vega, 33, a lunch maker for New York City school children, spent a week in intensive care on oxygen and blood thinners, which he’s been told to continue taking for three months.“I just have to watch out for any bleeding, and have to be careful not to cut myself,” Vega said.Gildersleeve, the New Hampshire stroke patient, was also sent home with a blood thinner. She gets physical therapy to improve strength and balance. She still has some numbness and vision problems that mean driving is out, for now.Doctors are unable to predict when or whether she’ll regain all her abilities.”I’m trying to remain positive about recovering,” she said. ’’I just have to be patient and listen to my body and not push too hard.”___Follow AP Medical Writer Lindsey Tanner at @LindseyTanner.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’ 7639

Hong Kong's embattled leader Carrie Lam has finally fully withdrawn a controversial bill that allowed extradition to mainland China and sparked three months of dramatic protests in the financial hub.The decision to cave in to one of protesters' five core demands marked a dramatic U-turn for Lam, who for months has refused to withdraw the bill."We must find ways to address the discontent in society and look for solutions," Lam said in a a video statement Wednesday evening. "After more than two months of social unrest, it is obvious to many that this discontentment extends far beyond the bill."But Lam refused to give ground on protesters' four other demands, including greater democracy for the city and an independent commission into police conduct, saying all investigations would be carried out by the existing Independent Police Complaints Council (IPCC).Instead, she announced the addition of a former education bureau chief and former judge to the IPCC. Lam said the government's priority now was to restore law and order to Hong Kong. "Let's replace conflicts with conversations and let's look for solutions," she said.Lam suspended the extradition bill in June after more than 1 million people marched against it, with protesters surrounding the city's legislature on the day of its planned second reading.That suspension did not satisfy protesters, who demanded the bill's complete withdrawal -- making it harder for the government to rush the law through at a later date. A withdrawn bill would need to go back to the beginning of the legislative process, whereas a suspended one could resume where it left off.In recent weeks, protesters' tactics have become increasingly violent as young people felt the government was refusing to consider their demands.Pro-Beijing lawmaker Michael Tien said that Lam's withdrawal may not stem their anger. "I believe the withdrawal of the bill ... may be too late because this movement has become more than the bill," he said.Activist Joshua Wong, who was last week arrested in a police sweep of activists and opposition politicians, wrote 2105

Holly Nunn is expecting her first baby in September, so it was with a bright pink shirt and a protruding belly that she joined an abortion rights rally outside the US Supreme Court on Tuesday."I'm here protesting today because no one should be forced to be pregnant when they don't want to be, and right now our right to make that most basic, fundamental decision is under attack," she said.Nunn was one of the many abortion rights supporters who gathered at statehouses, town squares and courthouses across the United States in a show of opposition to a wave of laws attempting to sharply restrict abortion."We will not go back," protesters in Charlotte, North Carolina, chanted."My voice, my choice," protesters outside the Georgia state Capitol in Atlanta shouted.More than 788

FALMOUTH, Kentucky — How you do find evidence of a 40-year-old murder? In pieces, mostly, according to Towson University associate clinical professor Dana Kollmann: Fragments of bone and enamel, rusted buttons and zippers, the rubber sole of a rotten shoe. Kollmann, a group of her criminal justice students and dozens of other volunteers spent the afternoon waving metal detectors and sifting through the topsoil at Kincaid Lake Park in search of these small tokens of 17-year-old Randy Sellers’s existence. Some were fresh off conversations with his family, where his parents passed around a picture of the smiling, dark-haired teenager and cried.“Not one of these students out here is getting a college credit,” Kollmann said. “They’re getting nothing but experience for this. They’re out here because they want to be here. They want to find Randy Sellers.”Sellers disappeared Aug. 16, 1980, according to police. Officers found him drinking at the Kenton County Fairgrounds that day and gave him a ride most of the way home. He vanished between there and the front door. Jack Isles, who identified himself Monday as a friend of Sellers's and claimed to have also been at the fairgrounds that day, said he often thought back to that night and regretted not driving Sellers home himself."I wish I could have told him to come on home," he said. "Let him go with me. I wish he was here, God-honest truth with you."Fourteen years later, serial murderer Donald Evans would confess to killing Sellers and burying his body at Kincaid Lake State Park — a killing in line with his self-described modus operandi, which involved preying on people at rest areas and parks. He drew a map leading investigators to the burial site.When they arrived and dug, however, they found nothing. The map was a lie or the work of a bad memory.It would take another three decades, Kenton County police Capt. Alan Johnson said Monday, for them to realize they might have misinterpreted Evans's drawing. “The park ranger here reviewed the case not too long ago,” he said. “They determined there was a possibility that the suspect may have held the map upside down.”Monday’s search was based on a new interpretation of the map, which Johnson hopes will finally unearth Sellers’s remains and allow his parents the relief for which they’ve waited most of their lives.“Any lead we get, it’s our obligation to investigate it to the fullest to bring closure to the family,” he said, adding later: “We’ve stayed in close contact (with his parents) through the whole process. They’ve been very appreciative and expressed a great deal of gratitude for the efforts going on.”According to Kollmann, any makeshift grave in Kincaid Lake State Park would have to be shallow. Anyone who dug further than two feet down would hit limestone.The clues, then, must have stayed in the top layer of soil or become tangled in the roots of trees as animals and weather shifted the landscape. That's if they’re really there.She and her students hope they are, she said.“It’s easy to become robotic in the field and to emotionally remove yourself,” she said. “I think you have to have that connection that we’re looking for people. People still missing after all this time.” 3234

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