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Pfizer announced Friday that it would submit a request to the FDA Friday for its COVID-19 vaccine to be granted Emergency Use Authorization.Earlier this week, Pfizer said that a final analysis of trial results showed the vaccine is 95% effective.“Our work to deliver a safe and effective vaccine has never been more urgent, as we continue to see an alarming rise in the number of cases of COVID-19 globally. Filing in the U.S. represents a critical milestone in our journey to deliver a COVID-19 vaccine to the world and we now have a more complete picture of both the efficacy and safety profile of our vaccine, giving us confidence in its potential,” Dr. Albert Bourla, Pfizer Chairman and CEO, said in a press release.Pfizer's two-shot vaccine has already been in mass production for months, and thousands of doses will be ready for delivery if and when the FDA grants authorization. Pfizer says that is on track to produce 50 million doses of the vaccine by the end of 2020 and plans to produce 1.3 billion doses of the vaccine in 2021.According to "Operation Warp Speed," the federal government's plan for distributing the vaccine, upon authorization, the drug will initially be rationed for high-risk populations and health care workers. Dr. Anthony Fauci, the nation's top infectious disease expert, says he believes a vaccine won't be widely available until April.On Wednesday, Pfizer announced that a final analysis of its vaccine candidate showed that of 40,000 participants who participated in the trial, 170 people had contracted the virus. Of those 170 people, 162 received only a placebo injection — meaning just eight out of the 20,000 people who actually received the vaccine contracted the virus.The company added Wednesday that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Pfizer's announcement comes as COVID-19 cases are spiking around the world. In the U.S. alone, about 2.5 million people have contracted the virus in the month of November alone. Hospitalizations linked to COVID-19 are at an all-time high, and deaths have begun to tick up in recent weeks. 2322

PINE VALLEY, Calif. (KGTV) - A suspected human smuggler was sentenced to 30 months in prison for barreling through a Border Patrol checkpoint, narrowly missing vehicles and severely injuring a border agent.Jorge Garcia-Osornio, 28, of Michoacán, Mexico, was charged with transporting certain aliens and aiding and abetting from the Nov. 14, 2017 incident.Border officials said Garcia was illegally in the U.S. when he approached a Pine Valley border checkpoint with two illegal immigrants hidden in the floor of his vehicle. As he neared the line of cars waiting, Garcia made an illegal U-turn and began driving in the opposite direction on the freeway, officials said.RELATED: Border Patrol tests body cameras in East San Diego CountyAgents began to pursue Garcia before he made another U-turn and headed back toward the checkpoint at speeds reaching 100 miles per hour.As he reached the checkpoint, officials said Garcia narrowly missed two vehicles and a border agent, and blasted through a metal sign, sending debris in all directions.“In committing his criminal act, Garcia not only placed the lives of those he smuggled in grave danger, but seriously injured a Border Patrol agent in the process,” Chief Patrol Agent Rodney S. Scott.RELATED: Border Patrol agent arrested in North San Diego County on drug, weapons chargesThat debris severely injured a nearby agent, who likened the blow to being "hit with a baseball bat." The agent was taken to a nearby hospital for treatment and has yet to return to duty.Garcia continued on for another three and a half miles at high speeds before exited a freeway and crashing into a hillside. One of the undocumented immigrants hiding in the vehicle told agents he "feared for his life."Garcia was arrested nearby after ditching his crashed vehicle. As part of his plea deal, he admitted to charges of driving the wrong way, using a dangerous weapon, and seriously injuring a border agent, among other charges.RELATED: Mother arrested by border agents in viral video released, reunited with familyThe man was expecting to earn between ,400 to ,000 for transporting each undocumented immigrant.“This defendant had no regard for the safety of his passengers, other drivers on the freeway or agents at the checkpoint,” U.S. Attorney Adam Braverman said in a release. “It’s a miracle no one died in this incident. Smugglers operate in a world where immigrants are just dollar signs, not people. 2527

Over 1 million children under the age of 19 in the United States have tested positive for COVID-19 since the pandemic began, the American Academy of Pediatrics and the Children’s Hospital Association said in a new report on Monday.According to the data, as of Nov. 12, 1,039,464 children have tested positive, accounting for 11.5% of all cases in states reporting cases by age.Pediatricians said 111,946 new child cases were reported last week, the highest weekly total of any previous weeks since the pandemic began."A smaller subset of states reported on hospitalizations and mortality by age; the available data indicated that COVID-19-associated hospitalization and death is uncommon in children," the report stated.In a press release, AAP President Dr. Sally Goza called the data “staggering and tragic.”"As a pediatrician who has practiced medicine for over three decades, I find this number staggering and tragic. We haven’t seen a virus flash through our communities in this way since before we had vaccines for measles and polio," Dr. Goza said. "And while we wait for a vaccine to be tested and licensed to protect children from the virus that causes COVID-19, we must do more now to protect everyone in our communities. This is even more important as we approach winter when people will naturally spend more time indoors where it is easier for the virus to be transmitted.”According to the data, 32 children have died from COVID in Texas, and 18 have passed away in New York City. 1499

PHILADELPHIA, Pa. – From China to Egypt and beyond, the halls of history span the globe.Yet, it’s been lonesome lately in those halls at some of the 35,000 museums across the country.“We, of course, wanted to reopen as soon as we could and safe a manner as we could,” said Melissa Smith, CEO of the Penn Museum in Philadelphia.It’s one of the few major museums to recently reopen to visitors, after coronavirus restrictions forced them to close their doors for months.“For the most part, it's business as usual with our exhibits,” Smith said.First, though, a task force of 35 museum employees needed to figure out what changes might be needed.“We had to look at a number of things,” Smith said.Among the changes: masks are a must, hand sanitizing stations are now located throughout the museum, clear partitions were installed to protect staff who interact with visitors and benches were marked off, so people can sit socially-distanced.Also, arrows now line the stairs and floors, carefully choreographing how visitors move through the exhibits.“They asked us to follow the arrows and it kind of was a different museum experience, but also I think very helpful, just because there wasn't any confusion,” said museum visitor Soheil Eshghi.There are a few other changes, too: some of the exhibits around the museum have touchscreens, so visitors can dig a little deeper into what’s on display and learn more. The museum is now giving out a disposable stylus to visitors, so they can safely use the touchscreens.Visitors said they don’t mind the changes and are just happy for the chance to come back.“I think that’s one of the things that I've been missing the most since all this shutdown started happening,” said Camille Lawhead, who was visiting the museum.Now, visitors no longer need to be missing it. 1813

PINE VALLEY, Calif. (KGTV) -- After Larry McNamer received a cease-and-desist letter from San Diego County officials, during the first week purple tier restrictions went into place, he said he will not back down."This is what courts are for. I'll fight it, I will fight it," the owner of Major’s Diner in Pine Valley said.In the letter, county officials noted he could face up to a ,000 fine for every violation under the state's guidelines, which includes not allowing guests inside."It could be ,000. I don't care because I can't afford to pay it, so I couldn't pay it if I had to,” McNamer told ABC 10News.McNamer said it all boils down to survival of this business and what he thinks is right in an uphill battle with the county and the state."They're going to have be a lot more fair about doling this out and understand that we zero cases up here [in Pine Valley],” he said.Even as he continues to serve up hot plates inside, McNamer said nothing changes when it comes to safety measures given by the state. He said guests are sat apart inside and have the option of dining outdoors if they choose.ABC 10News caught up with a couple from Alpine who grabbed a bite to eat Friday morning, not because Major's was the only diner open but they wanted to support him after seeing him on ABC 10News newscasts."We saw they were in trouble and in need of assistance, so we came to support them,” the supporter, Mark, said.ABC 10News asked Mark and his wife if they thought customers supporting restaurants who defy public health orders are contributing to the problem of COVID-19 cases rates surging, as restrictions continue to grow."Show me the data that these are sources of community spread because the data I see doesn't show that,” Mark said.McNamer said he's been receiving postcards and letters from people across the county supporting his choice of staying open to survive."It empowers you, it lets you know you're doing the right thing,” he said. 1967

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