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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
President Donald Trump's legal team is preparing to respond to special counsel Robert Mueller regarding the possibility of an interview, Rudy Giuliani told CNN Monday.Giuliani, one of Trump's lawyers, would not characterize the response. He's recently suggested that Trump and his lawyers would be making a final decision soon, but other sources have said the coming response would likely be another effort to counter the latest from Mueller and not a final offer.CNN reported last week that Mueller has offered to reduce the number of obstruction-related questions Trump would be asked by investigators. The President's lawyers had previously offered the special counsel written answers to obstruction questions and limiting the interview to matters before his presidential inauguration, which are largely confined to collusion.The special counsel indicated an interview with the President would include obstruction questions, but did cede that some answers on topics could be in writing. Trump's lawyers -- who are not in favor of any interview despite the President saying he wants to set the record straight with special counsel -- are seeking to limit the interview to collusion topics.The-CNN-Wire 1211

Read the letter from now-suspended Cincinnati Reds broadcaster Thom Brennaman apologizing for using a homophobic slur on-air Wednesday evening.As many of you know, I said something hateful on the air Wednesday night, something no one should ever say. Something that someone should ever think.Something that no one should ever feel.Something no one should ever hear.I could try to explain it or tell you about who I am and what I believe, but those things would all be excuses. The simple fact is, what I said was wrong.I used a word that is both offensive and insulting. In the last 24 hours, I have read about its history; I had no idea it was so rooted in hate and violence and am particularly ashamed that I, someone who makes his living by the use of words, could be so careless and insensitive. It’s a word that should have no place in my vocabulary and I will certainly never utter it again.I cannot erase what I have done. The only thing I can do is humbly apologize, accept the consequences of my actions, and resolve to be better and behave differently from now on.To the LGBTQ+ community – I am truly and deeply sorry. You should never be denigrated with crude and hateful language. I failed you and I cannot say enough how sorry I am.To the Cincinnati Reds and all Reds fans – You deserve better from me. I let you down and will work in whatever way I can to show that I am capable of learning from my mistakes and setting an example of which everyone associated with the Reds – management, staff, players, former players, and fans – can be proud.To Major League Baseball – Diversity is a strength of our game, and derogatory language has no place in the booth, on the field, or anywhere else for that matter. I am sorry for the shame I brought upon the game that has been so good to my family and me for nearly 50 years.I have spoken at length with Billy Bean, Vice President, and Special Assistant to the Commissioner of Baseball and an openly gay man, and Evan Millward, WCPO anchorman, who have been generous with their time and patience to help me understand the impact of my actions and provided me with resources to educate myself and work to become a more informed person. With their help, I am going to start improving my understanding of LGBTQ+ issues and not in a way to simply check a box to keep my job but to sincerely have an impact and change. I immediately plan to participate in Diversity, Equity, and Inclusion training and have reached out to PFLAG for resources and guidance.Regardless of what my future holds in broadcasting, my actions have forced me to reflect on who I am and how I want to be seen and thought of. I realize it is more important than ever for us to treat each other with dignity and respect. I need to be better and I must set a better example. I hope the LGBTQ+ community, the Reds and their fans, and the people of Cincinnati can find a way to think better of me. With all the humility I can muster, I ask for your forgiveness.This story was first reported by Thom Brennaman at WCPO in Cincinnati, Ohio. 3065
Rancho Bernardo, Calif. (KGTV) – Sheriff’s investigators and San Diego Police Detectives worked together to arrest three men after a series of small business burglaries in the Poway and Rancho Bernardo area.Robbers shattered the glass doors of Tony Pepperoni early Sunday morning and stole the restaurant’s safe."I was just happy it was at 5 a.m., and nobody was here and everyone's safe," said Sarah Dean, the manager of the pizza place. She said security cameras caught the burglary on camera.Pattaya Thai, the restaurant right across the street, was also broken into early Sunday morning.Dean believed the same thieves robbed both restaurants, which are in Rancho Carmel Village Center.The next break in the case came from more than three miles away in 4S Ranch on Sunday afternoon when a neighbor reported loud noise coming from behind the Boys and Girls Club.When deputies arrived, they found three men trying to crack the Tony Pepperoni’s safe.Sheriff’s investigators and SDPD detectives arrested and questioned Da'Shon Morales, 20, Jesus Ruiz Arias Jr., 19, and Fernando Vazquez Cruz, 20, on Sunday night in connection with burglary, possession of stolen property and other crimes. 1206
President Donald Trump Saturday threatened to withhold federal aid from California to assist with relief from wildfires burning up and down the state.Trump blamed the state's "poor" forest management for the devastation caused by the wildfires."There is no reason for these massive, deadly and costly forest fires in California except that forest management is so poor. Billions of dollars are given each year, with so many lives lost, all because of gross mismanagement of the forests. Remedy now, or no more Fed payments!" Trump tweeted. 547
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