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WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.
BRUSSELS, May 31 (Xinhua) -- Baby bottles containing the substance Bisphenol A (BPA) would have to be pulled from the shelves across the European Union (EU) starting from Wednesday, in a "milestone" move to better protect the health of EU citizens, an official said Tuesday."Due to the fact that there are uncertainties concerning the effect of the exposure of infants to Bisphenol A, the commission deemed it both necessary and appropriate to take action," said John Dalli, EU Health and Consumer Policy Commissioner."The aim is to further reduce the exposure of the most vulnerable part of our population, i.e. infants," he said.The ban, adopted in an EU directive in late January, would prohibit baby bottles containing BPA from placing on the EU market and import into the 27-member EU from June 1.Previously, the bloc had already banned the manufacture of the controversial baby bottles on March 1, and the industry has been withdrawing such products voluntarily.BPA is an organic molecule that is used in the manufacture of polycarbonate plastics, which are used to manufacture plastic materials, such as baby bottles.Traces of BPA can be released from plastic containers into the food they carry if these containers are heated at high temperatures. They may lead to early sexual development of children and could cause cancer, according to health officials.China would also prohibit the manufacture of feeding bottles containing BPA from June 1, while imports and sales of bottles containing BPA would be banned starting from Sept. 1.
BEIJING, June 11 (Xinhua) -- The Baidu Charitable Foundation (The Baidu Foundation) and The Bill & Melinda Gates Foundation (The Gates Foundation) founded a strategic charitable alliance here Saturday, in a bid to work for a healthy, smoke-free environment both in China and around the world.Li Yanhong, president of Baidu company, China's top online search engine operator, and Bill Gates, co-chair and trustee of the foundation under the names of the couple, attending the ceremony, both wore a shirt that said, "Say No to Forced Smoking."In his speech at the ceremony, Bill Gates said, "This will be a long-term, open-ended alliance. As a sponsor, Mr. Li and I would like to welcome more partners, and we expect to see more Chinese enterprises and all facets of society to focus on public health issues together."Li Yanhong also addressed the meeting, claiming, "Living healthy and green has become a common pursuit of mankind. We hope the alliance can bring together public efforts for this global cause, so that more people can benefit from our endeavor." ' The alliance's first action is to comply with the government ban on smoking in public places and refuse forced smoking, according to a press release from the foundations.Targeting "forced smokers," the alliance will carry out educational campaign through all channels of media to educate and promote self-awareness about the dangers of forced smoking. Moreover, it will also help existing smokers, especially those who are underage, by sharing scientific methods for quitting.Smoking is one of the world's eight primary causes of death, leading to lung disease, cancer, heart disease, low birth rate, fetal death, tuberculosis, high mortality and many other health issues. Smoking forces many families into poverty by causing both poor health and premature death.China ranks first in tobacco consumption and production in the world. China has 300 million smokers, and one in every three cigarettes smoked in the world is smoked in China. More than half of Chinese smokers are male; and more than 1 million people die from smoking related diseases each year.In addition, China has 740 million "forced smokers," whose health also suffers. The World Health Organization (WHO) notes that there is no safe level of second-hand smoke.This year, China published its 12th Five-Year Plan (2011-2015) that clearly stipulates for "implementing a full-scale ban on smoking in public facilities." This is the first time that tobacco control has been included as part of China's five-year plan for national economic and social development."Rules for Implementation of Public Facilities Health Management Regulations," effective since May 1st, also specifies to "ban smoking at all public indoor facilities," providing legal basis for non-smokers to protect their rights of health and to refuse "involuntary smoking."Aside from tobacco control, the strategic alliance co-founded by the foundations will also collaborate on a series of projects, such as AIDS prevention and control, in a joint effort to promote health for mankind.Founded in 2000, the Gates Foundation currently carries out charity projects in over 100 countries. Since establishing the Beijing Representative Office in 2007, the Gates Foundation has supported a range of health and development projects in China, including the advocacy of smoke-free environment, AIDS and tuberculosis prevention and control, and agricultural development and research projects.Launched in 2010, the Baidu Foundation is committed to use information technology for support of youth and disadvantaged groups, focus on the environment and promote social harmony.Ever since Baidu was founded, Li has actively pushed for tobacco control within the enterprise and the industry. He is the only Chinese member of the United Nation AIDS Prevention Senior Committee and also board member of the HuaXia Charity Foundation.
RIO DE JANEIRO, July 28 (Xinhua) -- Brazilians are eating a lot of rice and beans as well as high-calorie junk food lacking nutrition, a study released Thursday by the Brazilian Institute of Geography and Statistics (IBGE) found.According to the study, over 90 percent of Brazilians eat daily helpings of fruits and vegetables lower than the levels recommended by the Health Ministry (400 grams). Also,the consumption of sugary drinks (juices, fruit drinks and soft drinks) is twice as high as recommended by the ministry.Rice and beans, along with coffee and juices, are the most popular in Brazilians' diet. Teenagers are the main consumers of those drinks, drinking twice as much as adults. Men eat less greens and fruits than women, but drink five times more alcohol.In urban areas, the consumption of beer, soft drinks, sandwiches, and salty bread is higher. Brazilians in rural areas have a healthier diet, richer in rice, beans, fish, cassava flour, and sweet potatoes.Along with a lack of physical activity, the Brazilians' poor diet was cited as one of the main causes of obesity in the country. According to a Health Ministry study published in April, 48 percent of Brazilians are overweight, and 15 percent are obese.
SAN FRANCISCO, Sept. 6 (Xinhua)-- Yahoo on Tuesday fired Chief Executive Officer Carol Bartz and replaced her temporarily with the company's chief financial officer."On behalf of the entire board, I want to thank Carol for her service to Yahoo during a critical time of transition in the company's history, and against a very challenging macro-economic backdrop," said Yahoo Chairman Roy Bostock in a news release.The Yahoo Board of Directors appointed CFO Timothy Morse as interim CEO who will manage the company's day-to-day operations until a permanent chief executive is chosen.Carol Bartz, chief executive of Internet company Yahoo Inc, is shown in this undated publicity photo released to Reuters January 13, 2009. Before Yahoo's formal announcement, several news organizations and tech blogs posted an email reportedly from Bartz sent from her iPad to all employees of the company."To all, I am very sad to tell you that I've just been fired over the phone by Yahoo's Chairman of the Board. It has been my pleasure to work with all of you and I wish you only the best going forward."Bartz, 63, took over the Yahoo CEO role from co-founder Jerry Young in January 2009, when the company was struggling to stay competitive and profitable in a market dominated by Google. However, Yahoo never reached the heights she had foreseen.In the most recent quarterly earnings report in June, Yahoo reported net revenue of 1.1 billion U.S. dollars, down 5 percent from last year.Morse, 42, was hired as executive vice president and CFO at Yahoo in July 2009. "It is an honor to be selected for this role," he said in a statement Tuesday.Yahoo said it is starting a search for a new permanent CEO and plans to hire a "nationally recognized executive search firm" to assist in the effort.