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Scans of the lungs of the sickest COVID-19 patients show distinctive patterns of infection, but so far those clues offer little help in predicting which patients will pull through. For now, doctors are relying on what’s called supportive care that’s standard for severe pneumonia.Doctors in areas still bracing for an onslaught of sick patients are scouring medical reports and hosting webinars with Chinese doctors to get the best advice on what works and what hasn’t.One thing that’s clear around the globe: Age makes a huge difference in survival. And one reason is that seniors’ lungs don’t have as much of what geriatrics expert Dr. Richard Baron calls reserve capacity.“At age 18, you have a lot of extra lung capacity you don’t use unless you’re running a marathon,” explained Baron, who heads the American Board of Internal Medicine. That capacity gradually declines with age even in otherwise healthy people, so “if you’re an old person, even a mild form can overwhelm your lungs if you don’t have enough reserve.”Here’s what scientists can say so far about treating those who become severely ill.HOW DOES COVID-19 HARM THE LUNGS?The new coronavirus, like most respiratory viruses, is spread by droplets from someone’s cough or sneeze. The vast majority of patients recover, most after experiencing mild or moderate symptoms such as fever and cough. But sometimes the virus makes its way deep into the lungs to cause pneumonia.Lungs contain grapelike clusters of tiny air sacs called alveoli. When you breathe, oxygen fills the sacs and passes straight into blood vessels that nestle alongside them. Pneumonia occurs when an infection -- of any sort, not just this new virus -- inflames the lungs’ sacs. In severe cases they fill with fluid, dead cells and other debris so oxygen can’t get through.If other countries have the same experience as China, about 5% of COVID-19 patients could become sick enough to require intensive careHOW DOES THAT DAMAGE APPEAR?Doctors at New York’s Mount Sinai Health System analyzed 121 chest CT scans shared by colleagues in China and spotted something unusual.Healthy lungs look mostly black on medical scans because they’re full of air. An early infection with bacterial pneumonia tends to show up as a white blotch in one section of one lung. Pneumonia caused by a virus can show up as hazy patches that go by a weird name -- “ground glass opacities.”In people who get COVID-19 pneumonia, that haze tends to cluster on the outside edge of both lungs, by the ribs, a distinctive pattern, said Dr. Adam Bernheim, a radiologist at Mount Sinai.As infection worsens, the haze forms rounder clusters and gradually turns more white as the air sacs become increasingly clogged.HOW TO TREAT THE PNEUMONIA?There are no drugs so far that directly attack the new coronavirus, although doctors are trying some experimentally, including an old malaria treatment and one under development to treat Ebola.“The best treatment we have is supportive care,” said Dr. Aimee Moulin, an emergency care physician at the University of California Davis Medical Center.That centers around assistance in breathing when the oxygen levels in patients’ blood starts to drop. For some people, oxygen delivered through a mask or tubes in the nose is enough. More severely ill patients will need a breathing machine.“The goal is to keep the person alive until the disease takes its course” and the lungs begin to heal, explained Mount Sinai’s Dr. Neil Schachter.The very worst cases develop an inflammatory condition called ARDS -- acute respiratory distress syndrome — that floods the lungs with fluid. That’s when the immune system’s attempt to fight infection “is going crazy and itself attacking the lung,” Baron explained.Many things besides the coronavirus can cause the condition, and regardless of the cause, it comes with a high risk of death.WHAT ELSE IS IMPACTED?Severe pneumonia of any sort can cause shock and other organ damage. But in a webinar last week, Chinese doctors told members of the American College of Cardiology to watch for some additional problems in severe COVID-19, especially in people with heart disease. The worst off may need blood thinners as their blood starts to abnormally clot, and the heart itself may sustain damage not just from lack of oxygen but from the inflammation engulfing the body.Another caution: The sickest patients can deteriorate rapidly, something a hospital in Kirkland, Washington, witnessed.Of 21 patients who needed critical care at Evergreen Hospital, 17 were moved into the ICU without 24 hours of hospital admission, doctors reported last week in the 4639
Singer R. Kelly has been charged with two counts of engaging in prostitution with a person under 18 in Minnesota, prosecutors said Monday.Hennepin County Attorney Mike Freeman announced the charges against the performer, whose legal name is Robert Sylvester Kelly.Kelly is being charged by a summons, Freeman said, so it is unclear when he will respond to the new charges. His attorney has said it's not clear if his client has even met the woman and says this might be a case of "revisionist history."Freeman said the criminal complaint details an incident that occurred in July 2001 after a minor asked the singer for an autograph at a promotional event.Kelly gave the girl, then 17, his autograph and a phone number, the complaint states. When she called, she was directed to his hotel in Minneapolis and was met by someone she believed was a male member of his staff.The complaint says that when she met Kelly, the two made small talk before he gave her 0 to dance for him. After settling on the amount, she agreed. He took off her clothes and then his, and he touched her sexually while she danced, the documents say.He gave the victim VIP tickets to his concert, the complaint says. That enabled her to attend the 18+ concert without paying or showing her ID.The girl said that she discussed going to Chicago with Kelly but that the two lost contact after he changed the number he had given her, Freeman said.She contacted law enforcement in January to report the encounter, he said, after other allegations against Kelly surfaced. Attorneys corroborated some of her account with her brother, who saw her at Kelly's 2001 concert and confirmed that she told him she had been paid to dance for the singer.He said she didn't go into detail and he did not press her because she seemed uncomfortable talking about it."It is despicable that Mr. Kelly used his fame in order to prey on underaged girls," Freeman said in a statement.With charges pending against Kelly in New York and Illinois, Freeman said it's unclear when he will appear in court in Minnesota."While there are more numerous charges in the Illinois and federal cases, we wanted to make sure that our victim here in Minneapolis also receives a measure of justice," he said in a statement.Doug Anton, one of Kelly's attorneys, responded to the latest charges."Frankly I don't understand where the criminal activity exists in this matter. But I believe this highlights what has now become the absurdity of The bulk of the charges against our client.""When a top law-enforcement figure makes a public cry for the world to come and be famous by telling their sordid story, true or not, it inherently invites people to create revisionist history and put a different label on simple fan rockstar encounters."Anton said he didn't know if Kelly had ever met the woman."All we know is that yet another person has come forward either by their own desire or by being dragged in to the fray by prosecutors looking to make a name for themselves."Kelly pleaded not guilty to other charges FridayThe Minnesota indictment is the latest in a tangle of charges against Kelly, who's faced accusations of abuse and manipulation of underage girls and women for more than 20 years.On Friday, he pleaded not guilty in New York on several counts of racketeering, kidnapping, forced labor and sexual exploitation of a child. He was indicted in July by a federal court on accusations of transporting women and girls across state lines for "illegal sexual activity."Of the five unnamed women referenced in the indictment, three were minors.That indictment also alleges that he knowingly exposed at least one person to a sexually transmitted disease without disclosing it.He was indicted by grand juries in Illinois and New York in July on charges of recruiting women for sex, persuading people to conceal his sexual misconduct with teenagers, and buying back tapes that show him having sex with underage girls.He pleaded not guilty to the 13-count indictment in Illinois, which included four counts of producing child pornography and five counts of enticement of a minor to engage in criminal sexual activity.Kelly was also accused of videotaping himself having sex with at least four underage girls as far back as 1998.He'll next appear in Chicago court on September 4 for a status hearing on those charges.In February, he pleaded not guilty to an Illinois state court's charges: 10 counts of aggravated criminal sexual abuse against four people, including three underage girls. He was released on 0,000 bond but arrested and jailed in March after, authorities say, he failed to pay more than 0,000 in child support to his ex-wife. He was released days later after an undisclosed person paid the money owed.Kelly has remained in custody since July, awaiting trial on the 13-count indictment. 4851
Singer R. Kelly appeared in court today and his bond was set at million — 0,000 for each of the four people he’s charged with sexually abusing, the judge said.This was a bail hearing after 206
SANTA FE, N.M. – George R.R. Martin, the author of the books that inspired the TV show “Game of Thrones,” says he’s practicing social distancing amid the coronavirus pandemic. Martin provided the update to his fans in a blog post Tuesday, saying that he’s spending the time at his Santa Fe home writing the next book in the “Song of Ice and Fire” series. “Truth be told, I am spending more time in Westeros than in the real world, writing every day,” he wrote. “Things are pretty grim in the Seven Kingdoms… but maybe not as grim as they may become here.” As a 71-year-old man, Martin is in high risk age group for COVID-19, the illness caused by the virus. However, he says he’s taking the necessary precautions. “For those of you who may be concerned for me personally… yes, I am aware that I am very much in the most vulnerable population, given my age and physical condition,” he wrote. “But I feel fine at the moment, and we are taking all sensible precautions. I am off by myself in a remote isolated location, attended by one of my staff, and I’m not going into town or seeing anyone.”Martin, one of the most celebrated fantasy writers, went on to say that he can’t help feeling as if we are living in a science fiction novel.“But not, alas, the sort of science fiction novel that I dreamed of living in when I was a kid, the one with the cities on the Moon, colonies on Mars, household robots programmed with the Three Laws, and flying cars,” wrote Martin, :I never liked the pandemic stories half so well…”The writer also provided updates on the status of his businesses, including his bookstore, art installation and theater, as well as his nonprofit. 1674
ROCKFORD, Illinois — A U.S. Marshal who served a search warrant at an Illinois hotel on Thursday died from his injuries.Officials said Floyd E. Brown, 39, shot the McHenry County deputy through the door of the hotel room. He then fled in a silver vehicle. Authorities chased Brown at about 100 miles per hour on Interstate 55. Brown allegedly brandished a gun and pointed it at police during the pursuit, which ended with him spinning out in Logan County, Illinois.Brown was holed up in his vehicle on I-55, which was shut down in both directions. As of 3:20 p.m. Eastern he was still barricaded inside the car.Police said Brown has opened his car door several times but is staying in it. They are also interviewing others in connection to the incident.A SWAT team and crisis negotiators were called to the scene where Brown is barricaded. 851