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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

Force is with you, it is.A thoughtful 5-year-old boy included a Baby Yoda doll along with groceries and other items for firefighters battling wildfires in his home state of Oregon. Now, Baby Yoda is sharing the force with firefighters around the western U.S. and bringing smiles to thousands of fans.Carver told his grandmother he wanted to do something to help those on the front lines of the deadly wildfires. She heard of a donation drive helping firefighters and took Carver shopping to buy items to donate, according to CNN.Carver focused in on a Baby Yoda doll, so he sent it off in the care package with a note telling the firefighters, “here is a friend for you, in case you get lonely,” according to posts in a Facebook group dedicated to the doll’s adventures. 778

Firefighters in the Dallas-Fort Worth area are currently battling a massive warehouse fire at a plant that manufactures plastics.According to the Ft. Worth Star-Telegram, the massive fire is burning at a Poly-America warehouse in Grand Prarie, Texas. The company makes several products out of polyethylene plastic, including construction film and trash bags.According to the Star-Telegram, the fire was first reported at about midnight local time. A collapsed power line may be responsible for starting the fire.The fire has also spread to a nearby railroad car, which was full of paint products.The Grand Prarie Fire Department has asked those nearby to avoid the area.There are no initial reports of injuries. 719

Former President Barack Obama on Wednesday announced his first wave of endorsements for Democratic candidates vying for elected positions up and down the ballot this November.Obama endorsed 81 people for this first wave and is expected to endorse more ahead of the midterm elections. His office said Wednesday that the former president is also expected to campaign in several states for 2018 candidates.His endorsement list includes several people in high-profile races, including Gavin Newsom for governor of California, Stacey Abrams for governor of Georgia and Jacky Rosen for US Senate in Nevada.Former Obama administration officials and campaign alumni were among those who snagged Obama's backing. They include Colin Allred, Andrew Kim, Tom Malinowski, Lauren Underwood, Richard Cordray and Jill Schiller.Obama said in a statement that he is "proud to endorse such a wide and impressive array of Democratic candidates -- leaders as diverse, patriotic, and big-hearted as the America they're running to represent.""I'm confident that, together, they'll strengthen this country we love by restoring opportunity that's broadly shared, repairing our alliances and standing in the world, and upholding our fundamental commitment to justice, fairness, responsibility, and the rule of law," he continued.The 2018 midterms, now less than 100 days away, are largely seen as a referendum on President Donald Trump's first two years in office.Democrats need a net gain of 23 seats to wrest control of the House from Republicans. They need a net gain of two seats to take a Senate majority, although the path to get to that number is difficult.The endorsements add to other recent post-presidential efforts by Obama to shape the political landscape. 1751

Four people were killed and several others were wounded when a gunman opened fire in a Waffle House in Antioch, Tennessee.The mass shooting happened around 3:25 a.m. Sunday at 3571 Murfreesboro Pike near Hobson Pike.Metro Nashville Police Department officials named 29-year-old Travis Reinking, from Illinois, as a person of interest in the shooting, saying the vehicle the gunman used was registered to him.He has since been added to the Tennessee Bureau of Investigation's Top 10 Most Wanted list. Reports from the TBI described him as standing around 6'4'' tall and weighing approximately 180 pounds. He should be considered armed and dangerous.A ,500 reward is being offered for information leading to an arrest. Police said Reinking drove his pickup truck into the Waffle House parking lot around 3:18 a.m.. He sat in the truck for a few minutes before getting out and immediately shooting and killing two people outside of the restaurant with an AR-15 rifle.Officers said he then went inside and shot and killed another victim.Those three victims have been identified. Taurean C. Sanderlin, age 29 of Goodlettsville. He was an employee of the restaurant who was killed as he stood outside. Also killed outside was 20-year-old Joe R. Perez, of Nashville, who was a patron of the restaurant.The third death at the scene was 21-year-old Deebony Groves, of Gallatin. She was killed inside the restaurant.Police confirmed 23-year-old Akilah Dasilva, of Antioch, passed away at Vanderbilt University Medical Center after being injured inside the restaurant. A friend confirmed to NewsChannel 5 that Dasilva was a local musician who went by the nickname "Natrix."Two other victims were wounded by gunfire. They have been identified as 21-year-old Shanita Waggoner, of Nashville, and 24-year-old Sharita Hnderson, of Antioch.When the gunshots rang out, a patron ran to the restrooms. He was watching the gunman and rushed at him when he saw the gunman look down and fidget with the gun.The 29-year-old male patron wrestled the AR-15 away from the gunman. The patron suffered an elbow injury and other abrasions. He was taken to TriStar Southern Hills Medical Center and has since been released.Police said six of the eight people injured were shot.Witnesses said he was nude wearing only a green jacket and got away on foot after the patron took him down.  2424