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Radioactivity was detected on the oven, vacuum filter and bone crusher of an Arizona crematory where a deceased man who'd received radiation therapy was incinerated, according to a new case report. Worse still, a radioactive compound unrelated to the dead man was detected in the urine of an employee there."It is plausible that the crematory operator was exposed while cremating other human remains," Dr. Nathan Yu of the Department of Radiation Oncology at the Mayo Clinic in Phoenix and his co-authors wrote in the 529

SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Taco Bell announced this week changes to its menu, including the removal of nine menu items. Here are the items Taco Bell is removing from its menu: Beefy Mini QuesadillaChips & SalsaChipotle Chicken Loaded GrillerDouble Decker? TacoCool Ranch & Fiery Doritos Locos TacosDouble TostadaPower Menu BurritoXXL Grilled Stuft BurritoAlso beginning on Sept. 12, Taco Bell is changing its combo meal numbers. For instance, a three-taco combo will be the No. 1. The changes are an effort to declutter the menu. The menu will feature 10 lunch and dinner combos and three breakfast combos. 599

Research from Washington State University suggests cannabis could be used to relieve headaches, university researchers said in the Journal of Pain.According to the research, inhaled cannabis reduces self-reported headache severity by 47.3% and migraine severity by 49.6%. According to Washington State, the study was the first to use big data from headache and migraine patients using cannabis in real time. “We were motivated to do this study because a substantial number of people say they use cannabis for headache and migraine, but surprisingly few studies had addressed the topic,” said Carrie Cuttler, a Washington State University assistant professor of psychology, the lead author on the paper.Cuttler did caution that there could be a placebo effect, and that further research is needed.“I suspect there are some slight overestimates of effectiveness,” said Cuttler. “My hope is that this research will motivate researchers to take on the difficult work of conducting placebo-controlled trials. In the meantime, this at least gives medical cannabis patients and their doctors a little more information about what they might expect from using cannabis to manage these conditions.”The study also found no significant difference between the effectiveness of THC and CBD, two active ingredients in cannabis.One prior study indicated that cannabis was more effective than ibuprofen in reducing headaches, but that study used nabilone, a synthetic cannabinoid drug. 1480

Protesters in Denver took to the streets to march against police and the death of George Floyd on Thursday, which led to several violent encounters. In the midst of Thursday’s protest in Denver, a protester was run over by a car speeding through the protests. The incident was captured by a witness, Annabel Escobar, who posted the video on social media. After the protester was run over, dozens of others chased after the vehicle.It is unclear based on the video on what led to the incident.There is no word on the condition of the protester. The Denver protest was among dozens that took place nationally, as demonstrators call on the arrest of the officers involved in Monday's incident. 703