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LONDON — U.K. regulators say people who have a “significant history’’ of allergic reactions shouldn’t receive the new Pfizer-BioNTech vaccine while they investigate two adverse reactions that occurred on the first day of the country’s mass vaccination program. Stephen Powis, the national medical director for the U.K.'s National Health Service in England said Wednesday that health authorities were acting on a recommendation from the Medical and Healthcare Products Regulatory Agency. He says the agency has advised, on a precautionary basis, that "people with a significant history of allergic reactions do not receive this vaccination." Powis added that both people are recovering well.Dr. June Raine, head of the U.K.'s Medical and Healthcare Products Regulatory Agency, told Parliament on Wednesday that the reactions were not seen in clinical trials for the drug.“We know from the very extensive clinical trials that this wasn’t a feature,” Raine said, according to the Associated Press. “But If we need to strengthen our advice, now that we have had this experience with the vulnerable populations, the groups who have been selected as a priority, we get that advice to the field immediately.The FDA is currently weighing whether to approve the Pfizer-BioNTech vaccine for emergency use in the United States. 1325

LOS ANGELES (CNS) - Los Angeles County has reported 5,014 new cases of COVID-19 and 16 additional deaths, bringing the county's totals to 395,843 cases and 7,639 deaths as sweeping new health orders intended to halt the recent surge in cases go into effect.The number of county residents hospitalized with the virus rose from 1,951 Saturday to 2,049 Sunday, surpassing the 2,000 mark for the first time since the summer. Of those hospitalized, 24% are in intensive care.Health officials are urging people to stay at home as much as possible over the next three weeks."We have done this successfully before and we can do it again," County Public Health Director Barbara Ferrer said of efforts to stem the surge in new cases, deaths and hospitalizations.The new measures that go into effect Monday will remain until at least Dec. 20, according to the Los Angeles County Public Health Department.The additional safety modifications include the following changes to the existing Health Officer Order:-- Gatherings: all public and private gatherings with individuals not in your household are prohibited, except for church services and protests, which are constitutionally protected rights.-- Occupancy limits at various businesses; all individuals at these sites are required to wear face coverings and keep at least 6 feet of distance from others:-- Essential retail: 35% maximum occupancy;-- Nonessential retail (includes indoor malls): 20% maximum occupancy;-- Personal care services: 20% maximum occupancy;-- Libraries: 20% maximum occupancy;-- Fitness centers operating outdoors: 50% maximum occupancy;-- Museums galleries, zoos, aquariums, botanical gardens operating outdoors: 50% maximum occupancy;-- Mini-golf, batting cages, go-kart racing operating outdoors: 50% maximum occupancy;-- Outdoor recreation activities all require face coverings (except for swimming) and distancing: Beaches, trails and parks remain open; gatherings at these sites with members outside your household are prohibited. Golf courses, tennis courts, pickleball, archery ranges, skate parks, bike parks and community gardens remain open for individuals or members of a single household. Pools that serve more than one household may open only for regulated lap swimming with one person per lane. Drive-in movies/events/car parades are permitted provided occupants in each car are members of one household.-- Schools: All schools and day camps remain open adhering to reopening protocols. K-12 Schools and Day Camps with an outbreak (3 cases or more over 14 days) should close for 14 days.-- Closed nonessential businesses/activities: Playgrounds (with the exception of playgrounds at childcare centers and schools; card rooms;-- Restaurants, bars, breweries and wineries remain closed for in- person dining and drinking because of the high rates of transmission in the community, as customers are not wearing face coverings, which results in an increased chance of transmission of the virus.-- Restaurants, wineries and breweries remain open for pick-up, delivery and take-out. Breweries and wineries remain open for retail sales at 20% occupancy.Ferrer said Saturday the protocols for professional sports teams in the county would not change. "They are and will remain spectator-free."As for college sports, "We align with the state's collegiate sports directive. Should the state change, we at the local level will change."Ferrer said officials knew this surge was coming, but "None of us really thought the increase would be so big, across such a short period of time."She added that with a vaccine expected to be approved for distribution shortly, "the light is there at the end of the tunnel ... but we've got to get there."According to county estimates released earlier this week, every COVID- 19 patient in the county is passing the virus to an average of 1.27 people -- the highest transmission rate the county has seen since March, before any safety protocols such as face coverings and social distancing were in place.Based on that transmission rate, health officials estimate one of every 145 people in the county are now infected with the virus and transmitting it to others."This doesn't include people that are currently hospitalized or isolated at home," county Health Services Director Dr. Christina Ghaly said. "This is the estimate of people that are out and about and infecting others. They may not know they're infected. They may know they're infected and not be isolating. But they're out there and they're exposing other people to the virus."Ghaly said the number of people hospitalized due to the virus has jumped by 70% in the past two weeks, with the county now averaging about 300 new admissions daily."Based on the current estimate for (the virus transmission rate) and assuming that there's no change in people's behavior that would affect transmissions, there will likely be shortages in the number of hospital beds, and especially in ICU beds or intensive-care unit beds, over the next two to four weeks," she said.Ghaly noted that given the current transmission rate, the number of hospitalized patients could double in two weeks, and quadruple in a month. She said hospitals have "surge" plans to increase the number of beds, but the availability of health care workers to staff those beds and treat patients is more limited. 5345

LOS ANGELES (CNS) - The ShakeAlertLA app that drew criticism for not notifying users during the July 4 and 5 earthquakes will begin sending alerts for smaller quakes, officials announced Wednesday.Starting this month, the early warning system will alert residents of Garcetti, CalTech and the United States Geological Survey. The previous threshold was magnitude 5.0.``Every day we are communicating the importance of preparedness, so that every Angeleno has the tools and resources they need to build a better life, and then protect that life when disaster strikes,'' Garcetti said.``Updates to ShakeAlertLA will result in an even more responsive application, making our city stronger and our families safer.''The USGS ShakeAlert Earthquake Early Warning System for the West Coast detects significant earthquakes quick enough that ShakeAlerts can reach people a few seconds before shaking starts.``The USGS, through its scientific expertise, creates ShakeAlert earthquake early warnings, but in order to be successful, our public and private partners must develop technologies to use and distribute the alerts,'' said Doug Given, the USGS' earthquake early warning coordinator.ShakeAlertLA was developed in collaboration with USGS, AT&T and The Annenberg Foundation to combine USGS sensor network with mobile app technology, according to the Mayor's Office. It launched at the end of last year.When people receive a ShakeAlert notification, they are advised to take protective action, such as drop, cover and hold on.More information can be found at www.shakealert.org. 1582

LOS ANGELES (AP) — Mike Tyson showed glimpses of his destructive prime during the 54-year-old boxing icon’s return to the ring for a lively exhibition bout with 51-year-old Roy Jones Jr. on Saturday.Both fighters had impressive moments during a fight that was ruled a draw by the WBC judges at ringside.Tyson and Jones fought eight two-minute rounds, and both emerged smiling from a highly unusual event at Staples Center.The former heavyweight champion of the world’s return to the ring after a 15-year absence attracted international attention. Iron Mike did his best to show the form that made him a legend to a generation of boxing fans. 650

LOS ANGELES (KGTV) -- A 5.3 magnitude earthquake shook the Los Angeles area Thursday afternoon. According to the United States Geological Survey, the earthquake struck about 35 miles southwest of Channel Island Beach. At this time there are no reports of damage or injuries. The National Weather Service added that there is no risk for tsunami. Shortly after the quake, the Los Angeles Fire Department went into earthquake mode. According to the department, during earthquake mode, firefighters from all 106 neighborhood fire stations survey all 470 square miles in the greater Los Angeles area. The department says crews are now inspecting dams, power-lines and large places such as Dodger Stadium to ensure public safety.  772