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The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722
The Trump Administration wants to change the definition of a showerhead to let more water flow, addressing a pet peeve of the president who complains he isn’t getting wet enough.Publicly talking about the need to keep his hair “perfect,” President Donald Trump has made increasing water flow and dialing back long held appliance conservation standards — from light bulbs to toilets to dishwashers — a personal issue.But consumer and conservation groups said the Department of Energy’s proposed loosening of a 28-year-old energy law that includes appliance standards is silly, unnecessary and wasteful, especially as the West bakes through a historic two-decade-long megadrought.Since 1992, federal law has dictated that new showerheads shouldn’t pour more than 2.5 gallons of water per minute (9.5 liters). As newer shower fixtures came out with multiple nozzles, the Obama administration defined the showerhead restrictions to apply to what comes out in total. So if there are four nozzles, no more than 2.5 gallons total should come out between all four.The new proposal Wednesday would allow each nozzle to spray as much as 2.5 gallons, not just the overall showerhead.With four or five or more nozzles, “you could have 10, 15 gallons per minute powering out of the showerhead, literally probably washing you out of the bathroom,” said Andrew deLaski, executive director of the energy conservation group Appliance Standards Awareness Project.On the White House South Lawn in July, Trump made the issue personal:“So showerheads — you take a shower, the water doesn’t come out. You want to wash your hands, the water doesn’t come out. So what do you do? You just stand there longer or you take a shower longer? Because my hair — I don’t know about you, but it has to be perfect. Perfect.”DeLaski and officials at Consumer Reports said there’s been no public outcry or need for change. The Department of Energy’s own database of 12,499 showerheads showed 74% of them use two gallons or less water per minute, which is 20% less than the federal standard.“Frankly it’s silly,” deLaski said. “The country faces serious problems. We’ve got a pandemic, serious long-term drought throughout much of the West. We’ve got global climate change. Showerheads aren’t one of our problems.”Energy Department spokeswoman Shaylyn Hynes said the 2013 Obama definition of showerhead clashes with what Congress intended and the standards of the American Society of Mechanical Engineers.If the rule is adopted, Hynes said it would be “allowing Americans — not Washington bureaucrats — to choose what kind of showerheads they have in their homes.”Officials at the industry group Plumbing Manufacturers International did not respond to a request for comment.Appliance and plumbing energy and water conservation standards save consumers about 0 a year on energy bills, deLaski said.If people are having trouble getting water flowing in their shower, they should check their home’s water pressure and can replace a faulty showerhead for not much money, deLaski said.A 2016 test of showerheads by Consumer Reports found that the best rated showerheads — including a model — provided a pleasing amount of water flow and met federal standards, according to David Friedman, a Consumer Reports vice president and former acting assistant energy secretary.DeLaski said he has had a hard time understanding the president’s shower concerns.“If the president needs help finding a good shower, we can point him to some great consumer websites that help you identify a good showerhead that provides a dense soak and a good shower,” deLaski said. 3624

The Tampa Police Department is searching for a young man who was caught on camera doing a skateboard trick across a custom-painted car in Ybor City.A spokesperson for the police department said the case is being investigated as a felony criminal mischief. Detectives would like to speak with Dalton Newbury as a person of interest. According to those who have shared the video that's getting thousands of shares on Facebook, it was originally posted to Instagram by the skateboarder himself. The video has since been deleted from instagram. Tampa Police obtained the video and shared it on their YouTube page. Watch the video below: 661
The San Francisco Fire Department released a dramatic video of its rescue swimmers braving choppy waters to save a man on Wednesday. 140
The suspect in the deadly terror attack in New York wasn't only a driver for Uber. He also worked for its rival Lyft.Lyft said late Wednesday that Sayfullo Saipov drove for its ride-hailing app in the past but that it deactivated his account as soon as he was identified as a suspect in the attack.Saipov, a 29-year-old from Uzbekistan who was living in New Jersey, has been charged with federal terrorism offenses in connection with Tuesday's attack in Manhattan in which eight people were killed.Uber said Tuesday that Saipov started driving for it in New Jersey just over six months ago, making more than 1,400 trips. It also banned him from its platform after the attack.Lyft didn't provide details on how long Saipov drove for its app or how many trips he made. It's not unusual for drivers to work for both companies.Saipov's case is drawing renewed attention to the background checks that ride-hailing companies carry out on their drivers.Records show Saipov received multiple traffic citations in the past, including failure to equip a motor vehicle carrier with or maintain a required brake system.Both Uber and Lyft said they hadn't come across any complaints about Saipov's safety as a driver for them.New Jersey rules for ride-hailing services like Uber and Lyft require the companies to conduct criminal background checks, which are usually outsourced to specialist firms. Convictions for crimes like reckless driving automatically disqualify a driver.Uber applies different criteria for background checks depending on state regulations. In general, drivers cannot have more than three minor moving violations, such as speeding tickets, in the past three years.Lyft's website says potential drivers are screened for "driving incidents" but doesn't specify what would disqualify them.Both Uber and Lyft say they are in contact with law enforcement authorities over the New York attack."Our thoughts are with those affected by this tragic act," Lyft said. 1999
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