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SAN DIEGO (KGTV) — Making your own pasta doesn't have to be reserved for restaurants, you can try it out in your own kitchen.Cucina Sorella's gnocci (isn't it fun to say?) is a delicious take on the pasta, working in rapini leaves and ground beef for a dish that will leave you ready for more.Chef Joe Magnanelli walked us through his recipe, adding that his version isn't the only way you can serve up the pasta — should you try it yourself at home.The Dish:GnocciWhat You'll Need: 520
SAN DIEGO (KGTV) — It's something many of us do in San Diego: We see a picturesque sunset. Rummage around for our phone and open up its camera. Snap a photo and post it to social media.One San Diegan who did just that could see her photo named the Smithsonian's mobile photo of the year.Jacqueline Mckune was walking along the Pacific Beach boardwalk with a group of friends when they stopped to notice the serene orange glow of the evening's sunset."It happened to be a really good sunset too, we just took some previous pictures before with the whole group," McKune said, and that's when she noticed a particular subject against the scenic backdrop.RELATED: Where to capture the most picturesque scenes of San DiegoThe silhouette of man creating massive bubbles with rope strung between two poles against the soft glow of the sunset."So this guy’s making these huge bubbles … and I saw the colors with the sunset behind it," McKune said. Snap.She posted her photo to Facebook and soon, commentators suggested she submit it to a photo contest. After a quick search, she came across the Smithsonian's 16th Annual Photo Contest.RELATED: Convoy Street rooster mural highlights efforts for future neighborhood archwayThat was in June of 2018. McKune's photo would slowly climb with interest: First being a photo of the day, then an "editor's pick.""It was really, really exciting," McKune says. Now, it's a finalist in the mobile category against 9 other finalists picked from thousands of submissions from hunderds of countries. And locals can help make sure it takes home the prize by voting on the Smithsonian's website here."I’m hoping to get at least the photo category," McKune said. "I’m usually a dramatic person so [if I win] there’s probably a scream in there."Voters can submit one vote per day until March 29 at 2 p.m. for McKune's photo. 1855

SAN DIEGO (KGTV) — Mission Valley is in store to get an additional nearly 30,000 homes by 2050, according to a new plan the City Council unanimously passed Tuesday.The council voted 9-0 to pass the Mission Valley Community Plan, which would increase the number of allowed housing units in Mission Valley to 39,200. Currently, the area has about 11,200 units. The idea is to change Mission Valley's underutilized strip malls into mixed-use developments, where housing and commercial are under the same roof. "That dream, that American dream, that middle class security that is created by home ownership is now vanishing for a large segment of the population, and we can do better," said Jonathan Frankel, who heads the Mission Valley Community Planning Group. But Mission Valley is currently one of the cities most congested areas. Currently, the city says 600 people live and work in Mission Valley, but 40,000 commute in daily. As part of the plan, the city would add bridges and roads, plus an additional trolley stop and bike and walking paths. It would allow the people who do live and work in Mission Valley to get where they need to go, without a car. "The Mission Valley Community Plan Update is a no-brainer that will increase desperately needed housing stock, improve amenities for residents and will help the city meet its climate action goals,” Councilman Scott Sherman said in a statement. “I appreciate my council colleagues for approving this important community plan update.”The city aims to turn Mission Valley into a transit environment to help with the region's housing crisis and its climate action goals, a staff report says. 1654
SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459
SAN DIEGO (KGTV) — It's no secret: exploring San Diego is a bit different amid county health orders and the COVID-19 pandemic. But there are still ways to explore safely! We're continuing our weekly look at fun around town with safety in mind.Here are four options for this weekend:Visit Old Town San Diego: While many of Old Town's smaller museums and shops remain closed, areas like the state park, Bazaar del Mundo, and nearby eateries are open for visitors. Businesses that have reopened are abiding by distancing, so guests can feel safe shopping in stores. The state park is also a great area to get some fresh air and distance. More infoCounty fair fun: The San Diego County Fair may be canceled this year, but the Del Mar Fairgrounds is continuing to highlight fair exhibits, foods, and more online and at the fairgrounds. Fair food vendors welcome guests Friday - Sunday throughout June for kettle corn, hot dogs, and more treats and the fair is hosting virtual exhibits showcasing student artwork, photography, and livestock shows. More infoHit the beach: San Diego County's beaches are open for laying out and relaxing, and parking lots, boardwalks, and piers have reopened. With warm temperatures lingering this week, it's the perfect time for a beach day. Just remember to wear a facial covering and practice distancing when near non-household members. More infoCheck out the San Diego Air and Space Museum: Balboa Park's first museum to reopen will be on Friday, as the San Diego Air and Space Museum welcomes guests with increased safety measures like stylus pens for hands-on exhibits, sanitation procedures, and distancing between guests. More info 1673
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