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SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Talk about bad timing.A Tesla electric police patrol car in San Francisco ran low on power at one of the worst possible times last Friday -- during a pursuit.It's unclear exactly why the 2014 Tesla Model S 85 wasn't fully charged and lost juice at such an inopportune moment, according to Fremont Police Department's spokesperson, Geneva Bosques."It happens from time to time, especially if an officer returns to the station to take a report and then they never go back out in the street," she told CNN.The police officer driving the Tesla was pursuing a suspect who was wanted in connection with a crime in Santa Clara, according to Bosques. After confirming the license plate, the officer attempted a traffic stop, the car failed to yield and the driver took off at a high rate of speed, she said."Just realized I am down to six miles of battery on the Tesla, so I may lose it here in a sec," the officer driving the Tesla said, according to Fremont Police dispatch audio obtained via Broadcastify.Other police units were following behind to assist and ultimately took over the pursuit with help from California State Highway Patrol, according to Bosques. She said the chase was called off after 10 minutes when it was deemed unsafe because of the way the suspect was driving.California State Highway Patrol later found the suspect's car abandoned in San Jose.Fremont Police said they are still in their 6 months of a pilot program testing the integration of the Tesla with the department and that they are keeping track of all the data."We have no written policy regarding gas or charging, but the general guideline is that it should at least be half full at the beginning of the shift, which this car was," Bosques said.Bosques said last week's incident doesn't change the way the department feels about the performance of the car for patrol purposes. 1867

Special counsel Robert Mueller's federal grand jury has been extended for up to six months.The grand jury, based in Washington, DC, was seated for an 18-month term that began in July 2017 and was set to expire in the coming days.Under federal rules, the court is able to extend a grand jury's term for another six months if it is "in the public interest."Grand jury activity is secret, except following the 23-person group's approval of criminal indictments.Chief Judge Beryl Howell of the DC District Court, who oversees the Mueller grand jury, granted the extension. She does not sit in on its sessions. 617

Sen. Cory Booker, D-New Jersey, has endorsed former Vice President Joe Biden in the race for the Democratic presidential nomination.Booker made his announcement in a tweet early Monday morning."The answer to hatred & division is to reignite our spirit of common purpose. @JoeBiden won't only win - he'll show there's more that unites us than divides us. He'll restore honor to the Oval Office and tackle our most pressing challenges. That's why I'm proud to endorse Joe," Booker tweeted.Booker's endorsement is the latest boost in momentum for Biden's campaign, which has taken off since the former vice president's win in the South Carolina primary. Since that win, Biden racked up big wins in Super Tuesday primaries and picked up major endorsements from moderate candidates like Booker, Mike Bloomberg, Amy Klobuchar and Pete Buttigieg.Biden currently holds a slight delegate lead over Sen. Bernie Sanders (I-Vermont), with 664 delegates to Sanders' 573.Booker previously sought the Democratic presidential nomination and appeared in a number of debates, but dropped out prior to the Iowa caucuses. 1117

TAMPA, Fla. — A new academic logo for the University of South Florida that cost nearly ,000 to design and refine is a huge dud with students, who have started a petition to bring back the old academic logo.Call it a bull brouhaha!USF students are not happy with the new school logo that’s already gone through a redesign and is now costing the bay area-university approximately ,000. The new logo is a bright arty bull with ornate “USF” lettering and it debuted in September 2018. And after the university received negative feedback on the logo, they made slight revisions this month. The revisions were made "to address feedback from our audiences, as well as campus communicators regarding evolving challenges with printing, signage and apparel applications," according to a spokesperson for the university.Calling it everything from “laughable” to a ripoff of finance company Merrill Lynch’s own bull mascot, students have started a petition to bring back the old USF logo: the “U” with bull horns.Other complaints about the logo introduced in September 2018 involve the new logo’s colors, which are a brighter green and yellow than the school’s classic dark green and gold.After paying nearly ,000 for a redesign — the changes include a shorter bull tail, slightly different leg placement, a connection of the front leg to the rest of the body — USF says they’re sticking with the new logo.Breaking down the cost of the logo, according to USF:The initial logo design done in September 2018: ,000Adapting the design and creating logo lockdowns for all college, schools, programs, departments and other entities across the University: ,450March 2019 design changes/refinements: ,835Check out a transparent overlay we designed to compare the old logo to the new logo. (*note the color of the logo did not change, the old logo is just lowered to 35 percent opacity to show the difference in designs)Approximately six months ago, USF student Alexis Loukota started 1991