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A new study suggests misguided antibodies created as a response when someone is infected with the coronavirus could be the cause behind both more severe COVID-19 symptoms and those who report having symptoms for months after initially recovering.Researchers at Yale University found that COVID-19 patients they studied had high levels of antibodies that had turned on them; these wayward antibodies blocked antiviral defenses, wiped out helpful immune cells and attacked the body in several areas including the brain, blood vessels, liver and gastrointestinal tract.“Covid-19 patients make autoantibodies that actually interfere with immune responses against the virus,” Aaron Ring, an immunobiologist at Yale and senior author on the study, told The Guardian.Autoantibodies are antibodies that attack the body’s own proteins by mistake and disrupt their normal functions.“We certainly believe that these autoantibodies are harmful to patients with Covid-19,” said Ring. He added that the harmful effects of these autoantibodies could continue well after the initial infection has been overcome. He said antibodies can last for a long time, and if they are misguided in their attacks, the effects of their attacks on the body could also last a while.The study, which has yet to be peer reviewed and formally published, looked at antibodies from 194 COVID-19 patients and hospital workers with a range of symptoms and severity of symptoms.Other conditions, like lupus, multiple sclerosis and rheumatoid arthritis, are also made worse by the immune system malfunctioning and attacking the body. 1600

A top figure in President Donald Trump's orbit has been granted immunity in the investigation into hush money payments made to two women who alleged they had affairs with Trump, a source familiar with the matter told CNN Friday.Trump Organization chief financial officer Allen Weisselberg was granted immunity by federal prosecutors for providing information about Trump's former personal attorney Michael Cohen. The Wall Street Journal first reported the development.A lawyer for the Trump Organization declined to comment. A spokesperson for the US attorneys office also declined to comment. Weisselberg did not respond to the Journal's request for comment.Weisselberg was subpoenaed last month to testify as part of the ongoing criminal investigation into Trump's former attorney Michael Cohen, the Journal reported.At the time, a former Trump Organization employee told CNN that Weisselberg being subpoenaed was the "ultimate nightmare scenario for Trump" because Weisselberg knows "anything and everything" about the finances of the Trump Organization."Allen knows where all the financial bodies are buried. Allen knows every deal, he knows every dealership, he knows every sale, anything and everything that's been done -- he knows every membership. Anything you can think of," said the person, who was not making any specific allegations about the Trump Organization's finances.The Wall Street Journal reported Thursday that the CEO of the National Enquirer publisher, David Pecker, was also granted immunity in the Cohen case for providing details of the payments to prosecutors.On Tuesday, Cohen pleaded guilty to eight criminal counts, and implicated the President by admitting in court that he "in coordination and at the direction of a candidate for federal office," kept information that would have harmed Trump from becoming public during the 2016 election.The-CNN-Wire 1891

A survey of parents across the United States estimates that one in 40 children has autism spectrum disorder, according to a study published Monday in the journal Pediatrics.In other words, the condition was reported in 2.5% of children, representing an estimated 1.5 million kids ages 3 to 17.A report released this year by the US Centers for Disease Control and Prevention estimated the prevalence at one in 59 children or about 1.7%, based on 2014 data."Prevalence is not growing that rapidly, although the CDC's data suggests it is still growing," Thomas Frazier, chief science officer of the advocacy organization Autism Speaks, said in an emailed statement. He was not involved in the new report."What is happening is that these studies use methods that are a bit more liberal and inclusive than the CDC's methods," Frazier said, adding that he prefers the CDC's numbers but understands "that they are likely a bit conservative."The new study is based on the 2016 National Survey of Children's Health, which was conducted by the US Census Bureau and which collected information from parents of more than 50,000 children up to age 17. To be included in the estimate, parents would have had to report that their child had ever received a diagnosis of autism spectrum disorder and that they currently had the condition.The new numbers were also slightly lower than those in the 2017 National Health Interview Survey. It estimated that 2.76% of children had ever received such a diagnosis, which the authors of the new report note is a broader definition.The fact that the new study relies on parental reporting -- which is not validated by health and education records, as in the CDC report -- may be a limitation despite the broad scope of the research, the authors say.Frazier said the 1-in-40 figure is "generally consistent with previous parent surveys and other direct prevalence studies where researchers directly screen for and attempt to identify autism."The parents in the new study also reported more difficulties getting the health care their children need, versus those with Down syndrome, or other behavioral disorder, such as attention-deficit hyperactivity disorder."Though we've seen progress in recent years, this confirms what we know from our parents -- that many children face unacceptable delays in getting a diagnostic evaluation, even after parents, teachers or other caregivers have recognized the signs of autism," Frazier said.In the new study, more than a quarter of children with autism spectrum disorder were taking medication for symptoms related to the condition, and nearly two-thirds have received "behavioral treatments" in the past year, the study says.It also found a higher prevalence for autism spectrum disorder among certain groups such as boys, children of single mothers and households below the federal poverty level, compared with those at least four times above that income threshold.The differences between the new study's numbers and those of the CDC study might be explained by the years they were conducted, the ages of children studied and where they lived, according to the new study.The CDC report was based on data collected from 11 communities across the country but was not necessarily nationally representative, according to that report's co-author Daisy Christensen, surveillance team lead in the developmental disabilities branch of the CDC's National Center on Birth Defects and Developmental Disabilities."Parents know their child best," Christensen, who was not involved in the new report, previously told CNN. "We want to encourage parents to be aware of their child's development, to be aware of the milestones that children achieve."Autism spectrum disorder, a lifelong developmental disability, is characterized by problems with communication and social interaction with accompanying repetitive behavior patterns.The authors note that it's difficult to compare the new report with prior iterations due to updates in how the survey collected its data and how questions were worded."We cannot tell what proportion was explained by internal survey changes rather than external factors," the authors wrote.Still, the report comes as estimated prevalences of the disorder have been rising for decades."Over the '80s and '90s, the diagnostic criteria expanded to include more children," Christensen said, "so I think that's definitely a possibility for the increase that we've seen."In the past, more than half of children identified with autism also had intellectual disability, and now it's about a third, she said. "And that's really consistent with identifying children who are perhaps at the milder end of the spectrum."The new study's authors also note that universal screening recommendations in the 2000s may have led to a rise in prevalence among younger children, for example."Because there is no biological marker, [autism spectrum disorder] is a particularly challenging condition to track," the authors note.But understanding how common it is allows health experts to distribute resources and get families the help they need, according to Frazier."Having prevalence estimates -- even if there is some variation -- helps us to advocate for improved screening, diagnosis, interventions and supports," he said. 5314

A proposed state fund would pay rent for people on the brink of eviction to help them avoid homelessness.The 0 million fund is a key part of Gov. Gavin Newsom's budget proposal to address the state's homeless crisis. The fund, called the California Access to Housing and Services fund, could also be used to support the creation of more housing units and help stabilize board and care housing facilities. Newsom is proposing a .4 billion plan as part of his annual budget. Of that, 5 million would go to investments in Medi-Cal. The proposal also calls for the state using its own excess land for the site of new shelters. That includes open space near freeways, decommissioned hospitals and fairgrounds. The Del Mar Fairgrounds board has held preliminary discussions adding housing on the property. In San Diego County, excess property locations are also in downtown, El Cajon and Oceanside. An additional location deemed excess has instead been assigned to serve as a shelter for migrants seeking asylum. Jewish Family Service will operate the facility, and has requested the location not be disclosed due to security reasons. The current migrant shelter at the old family courthouse downtown at 6th and Cedar will close Dec. 31 for redevelopment. 1266

A Virginia man says he was fired from his job at a shipyard for refusing to remove a hat supporting President Donald Trump. The Virginian-Pilot reports that Dave Sunderland was fired last week from Newport News Shipbuilding. The private firm builds the nation’s aircraft carriers and some of its submarines. Sunderland said the human resources department said he violated a policy that bars yard workers from “campaigning” while on the job. Sunderland wore the hat as he walked from his car to his work area inside the gates, and sometimes during a safety meeting at the beginning of his shift. A spokesperson for Newport News Shipbuilding says the company doesn't allow political campaign or partisan political activities on company property. 751