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Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said. 3711
Research by the RAND Corporation American Life Panel found that Americans over the age of 30 have been drinking more alcohol in 2020 than they did a year ago.The journal Jama Network Open published the results Tuesday.Researchers surveyed more than 1,500 people between the ages of 30 and 80 in 2019 and 2020. They found a 14% increase in drinking during the pandemic.On average, alcohol was consumed one day more per month by 3-of-4 adults, researchers said.Researchers added that it's essential to watch for whether the increases in alcohol drinking continues over the pandemic, and whether it will lead to physical and mental health consequences. 657
RAMONA, Calif. (KGTV) — A local mother said her son and another teenager were attacked during a Black Lives Matter protest in Ramona.Heidi, who wanted to use only her first name, said her son Miguel had been peacefully protesting during the first week of June. Miguel recently graduated from high school. “I feel like our new generation is going to change something in the future,” he said.During the protest on June 5 in Ramona, he and his mother said men attacked him and his friend. She said the attack was unprovoked. RELATED: Man says he was sucker punched at Imperial Beach protestIn video sent to ABC 10News, the unidentified man yelled, “I’m from Ramona!” He then punches a 16-year-old protester. Miguel said he moved his friend out of the way and that’s when the same man attacked him.“He hits me, I try to grab him so he won’t go away,” Miguel said. “Next thing… I get hit in the back. I was unconscious after that.”Heidi said the second hit came from a different man. She was at home when the Sheriff’s Department called her. “As a mother, it was very heartbreaking,” Heidi said.This is the second attack on protesters caught on camera that ABC 10News has covered recently. On June 7 in Imperial Beach, a man sucker-punched Marcus Boyd, a local businessman.Heidi said Miguel went to Pomerado Hospital with a concussion, sprained neck, and jaw. She is disappointed with where the Sheriff’s investigation stands. “Our officer was very, very nice. Are they doing all we think they should do? No.” Heidi said.Miguel plans to go to EMT school and eventually become a law enforcement officer. He said despite being attacked, he would still protest for causes he believes in.“I don't want my son to get hurt. but that being said, I'm not raising a man that's going to be afraid to voice his freedom of speech and liberty,” Heidi said.A Sheriff’s spokesperson told ABC 10News: “Deputies from the Ramona Sheriff’s Substation took a report about this incident. This is being investigated as a battery. As this is an open and active investigation, we can’t go into a lot of details to avoid jeopardizing the outcome of the case.” 2137
RADCLIFF, Ky. (AP) — A Kentucky couple who refused to sign a self-isolation order when one tested positive for the coronavirus said they were placed under house arrest.Elizabeth Linscott of Radcliff told news outlets she was tested July 11 for COVID-19 because she wanted to visit her grandparents and received a positive result the next day. Linscott said the health department emailed her a form to sign that said she would check in daily, self isolate and let officials know if she has to be treated at the hospital.The form said the isolation order is to “prevent the introduction, transmission and spread of the 2019 novel coronavirus in this state.”Linscott said she declined to sign because of one sentence: “I will not travel by any public, commercial or health care conveyance such as ambulance, bus, taxi, airplane, train or boat without the prior approval of the Department of Public Health.”“I could not comply to having to call the public health department prior if I had an emergency or I had to go pick something up for my child or myself as a necessity and could not wait,” Linscott said.When she declined to sign the form she said she was told the case would be escalated and on July 16, Linscott said she and her husband were placed under house arrest with ankle monitors.Hardin County Sheriff John Ward said his office was on hand to execute court documents from a Hardin County Circuit Court judge. It was the first time his office executed such an order, he said.Lincoln Trail District Health Department spokeswoman Terrie Burgan declined to comment on the matter to protect the privacy of the family. 1630
Restaurants in Los Angeles County will be open for delivery, take-out and drive-thru services only for three weeks beginning Wednesday in the hopes of preventing the spread of COVID-19, according to The Los Angeles Times and KABC-TV.Restaurants, bar, breweries and wineries in LA County had been open with outdoor seating only. However, officials have moved to restrict all in-person dining as cases in the county have spiked in recent weeks — just as they have across the country.Breweries and wineries can continue selling alcohol in a retail setting."To reduce the possibility for crowding and the potential for exposures in settings where people are not wearing their face coverings, restaurants, breweries, wineries and bars will only be able to offer take-out, drive thru, and delivery services," the county's Department of Public Health said in a news release. "Wineries and breweries may continue their retail operations adhering to current protocols. In person dining will not be allowed, at minimum, for the next 3 weeks."The restrictions came after county officials warned that further action would be taken if the county's five-day average of daily cases rose above 4,000 a day. KABC-TV reports that on Sunday, the four-day average sat at 4,097 a day.The restrictions threaten countless restaurant owners in the Los Angeles area, as well as the thousands of people those owners employ. Several restaurant owners told The Los Angeles Times that the restrictions come just as they were expecting a boost in business for the holidays. Some business owners say they are still paying off renovations implemented to expand outdoor dining.In the last week, California has reported about 11,000 new cases of COVID-19 each day — a record since the pandemic began. 1774