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SAN DIEGO (KGTV) - The City of San Diego said Friday Lime Bike, Bird, Skip Scooters and Lyft had violated its terms of operation in regards to geofencing and other scooter operating restrictions. Geofencing forces riders to slow down to 8 miles per hour in busy areas “like Balboa Park and our boardwalks,” San Diego Mayor Kevin Faulconer wrote on Twitter. Bird had violations in nine different San Diego locations on July 13 and 14. Lyft and Lime Bike had violations in seven areas during that time, city officials said. The mayor proposed last fall to require geofencing at nine locations:Boardwalks in Mission Beach, Pacific Beach and La Jolla beach areasDowntown EmbarcaderoPromenade behind the San Diego Convention CenterMartin Luther King Jr. Promenade DowntownBalboa ParkNTC ParkMission Bay Park“SD’s new scooter regulations are in place and we’re serious when it comes to enforcing rules that keep operators honest and users safe,” Faulconer posted. “We’re holding scooter companies accountable and bad actors will no longer be allowed to do business in San Diego.” RELATED: Amid safety concerns, San Diego mayor wants geofencing to slow down dockless scootersThe companies were ordered to comply with geofencing rules by July 29 or cease operations in San Diego. 1279

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) -- Sunday, San Diego Police will be enforcing scooter, bike and pedestrian safety at several beaches. Throughout the day, officers will be conducting the operation in unspecified areas of Pacific and Mission beaches between 9 a.m. and 5 p.m.During the enforcement period, officers will be looking for traffic violations made by drivers, bicyclists and pedestrians.RELATED: CA scraps helmet mandate for motorized scootersThe department says it will be paying special attention to drivers speeding, making illegal turns, failing to stop for signs and lights and failing to yield to pedestrians.Officers will also be watching when pedestrians cross streets illegally or fail to yield to drivers with the right of way.RELATED: Increase in child dockless scooter injuriesAccording to police, the number of pedestrian deaths is rising as more people use non-motorized transportation. In 2013, the department says 701 pedestrians died in California, marking 23 percent of all roadway fatalities.The department recommends the following tips to stay safe: 1086

SAN DIEGO (KGTV) - The fate of a local little league is up in the air after a string of costly break-ins dating back six months.At the Sunshine Little League fields off Federal Boulevard, it's not all sunshine and baseball joy."It's unfair, and I just don't like it," said Isaac Lopez, 11, who plays in the league.Two different break-ins were discovered over the weekend. Locks were broken and doors were pried open."It's upsetting. These kids don't deserve this," said league president John-Mario Pujol.The thief cleaned out the snack bar. Stolen from storage sheds: umpire gear and all of the equipment for the kids in the older division, including bats, helmets, gloves, and catcher's gear sets."It's just so petty. Kids are one thing that should be hands off. Stay away from messing with the youth," said Pujol.The break-ins are the latest in a series dating back six months, with more than six in all. In those cases, more equipment and food disappeared. In other incidents, homeless individuals have been found sleeping in the sheds. The total loss from theft and damage is nearly ,000. Pujol says for a low-income community, the loss is painful."We're hurting, in a tough position," said Pujol.The position is made tougher because of COVID-19. Fundraisers have been canceled. There are practices, but no games means no revenues."As of now, we don't have the opportunity to start our league back up. We'd have to generate revenue first," said Pujol."We have to stay at home because of COVID-19, but we get to go to baseball practice and get the energy out. We get to see friends, and it's good to know that something hasn't changed ... I would just be disappointed if we had to give it all up," said Lopez.A Gofundme campaign has been set up to help buy new equipment and pay for other expenses. 1811

SAN DIEGO (KGTV) -- The Del Mar Fairgrounds get transformed into a small, mobile city during the traveling performance of Cirque du Soleil as the focus shifts to feeding hundreds of artists, technicians and staff. Each Cirque du Soleil audience is transported to another world watching art unfold on the stage, but behind the scenes is another form of art. “Culinary is one of those few fields left in the world where you can be artistic, can be a form of expression every day.” Chef Scott Veneklase is one of Volta’s four chefs, creating eclectic menus featuring food from all corners of the world. “We try to do a bit of everything, German food, Japanese food, today Italian.” Because the performers come from 25 different countries, their meal is often the closest connection they’ll have to their home. Each day is a brand new menu. “Even if it’s just a little flavor from home for them it makes all the difference in the world.” “It’s so important to feed artists and to provide something they’ll like, that way they won’t feel so far from home.” Chef Veneklase and his team are responsible for feeding over 126 athletes and artists. each with unique dietary needs. “The artists are always going to be very, very clean, say we’re designing a menu have to be incredibly conscious about it.” “It’s basically opening and closing a restaurant every month, so it’s a huge challenge of creativity.” The kitchen staff is always first to arrive on sight and the last to leave.Then they do it all over again in 10 days in a new city. “We’re a close group. We all ran away and joined the circus.” It’s a fast paced lifestyle they live for. “We get to explore, we get to travel the world.” Creating new art in every stop. 1727