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2025-05-31 13:47:26
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  济南早射哪里治   

WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday revoked its approval of Avastin for treating the breast cancer after concluding that the drug has not been shown to be safe and effective for that use.Avastin will still remain on the market as an approved treatment for certain types of colon, lung, kidney and brain cancer."After reviewing the available studies it is clear that women who take Avastin for metastatic breast cancer risk potentially life-threatening side effects without proof that the use of Avastin will provide a benefit, in terms of delay in tumor growth, that would justify those risks," FDA Commissioner Margaret Hamburg said in a statement. "Nor is there evidence that use of Avastin will either help them live longer or improve their quality of life. "Avastin's risks include severe high blood pressure; bleeding and hemorrhaging; heart attack or heart failure; and the development of perforations in different parts of the body such as the nose, stomach, and intestines.Avastin was approved for metastatic breast cancer in February 2008 under the FDA's accelerated approval program, which allows a drug to be approved based on data that are not sufficiently complete to permit full approval. After the approval, the drug's sponsor, Genentech, completed two additional clinical trials and submitted the data from those studies to the FDA. These data showed only a small effect on tumor growth without evidence that patients lived any longer or had a better quality of life compared to taking standard chemotherapy alone -- not enough to outweigh the risk of taking the drug.FDA's Center for Drug Evaluation and Research, which is responsible for the approval of this drug, ultimately concluded that the results of these additional studies did not justify continued approval and notified Genentech it was proposing to withdraw approval of the indication.Genentech did not agree with the Center's evaluation of the data and, following the procedures set out in FDA regulations, requested a hearing on the Center's withdrawal proposal, with a decision to be made by the Commissioner. That two-day hearing, which took place June 28-29, included recommendations from the FDA 's Oncologic Drugs Advisory Committee, voting 6-0 in favor of withdrawing approval of Avastin's breast cancer indication.

  济南早射哪里治   

  济南早射哪里治   

VIENNA, Oct. 31 (Xinhua) -- Visiting Chinese President Hu Jintao met his Austrian counterpart Heinz Fischer here Monday and laid out a multi-point proposal to further strengthen bilateral cooperation.During the meeting, Hu spoke highly of the ties between the two countries, saying that China values its relations with Austria and is willing to join hands with Austria to elevate bilateral ties to a higher level.Then he proposed that the two sides enhance their political relationship based on equality and mutual trust, continue with their frequent high-level contacts and steer bilateral relations from a strategic and long-term perspective.The two countries should also expand their mutually beneficial economic and trade relations, he said, while calling for concerted efforts to fight trade protectionism and encourage mutual investment so as to achieve a balanced, diversified and sustainable trade relationship.Visiting Chinese President Hu Jintao (L) shakes hands with his Austrian counterpart Heinz Fischer (R) in Vienna, Austria, Oct. 31, 2011. Hu Jintao held talks with Heinz Fischer in Vienna Monday.China is willing to import more goods from Austria and to work with Austria to seek cooperation with third countries in Central and Eastern Europe, said the Chinese president, who also asked Austria to create favorable conditions for Chinese investors in Austria.Meanwhile, Hu urged Vienna to play a more active role in pushing for the EU's recognition of China's full market economy status and for a lift of the bloc's restrictions on high-tech exports to China.In the culture sphere, the two sides should promote people-to-people exchanges and boost cooperation in culture, eduction and media among others, Hu said.In addition, the two countries should also deepen cooperation in multilateral mechanisms to jointly push for a more just and fairer international political and economic order, Hu said.China, he added, is willing to enhance cooperation and coordination with Austria on important issues such as global economic governance, climate change, energy security and peaceful settlement of international disputes.History has proven that as long as the two sides understand and support each other, and respect each other's social systems and development models, the bilateral relationship can achieve long-term, steady and healthy development, Hu said.Fischer, for his part, said that he fully agrees with Hu's proposal, adding that his country is willing to enhance cooperation with China in culture, science and technology and tourism and expand coordination in the United Nations and other multilateral frameworks.

  

HONOLULU, United States, Nov. 13 (Xinhua) -- Chinese President Hu Jintao and leaders of other Asia-Pacific Economic Cooperation (APEC) members met in Honolulu, Hawaii, Sunday to find ways to speed up regional economic integration, free trade and investment, and economic and technological cooperation.The annual meeting, hosted by U.S. President Barack Obama in his home state, is being convened at the JW Marriott Ihilani, Honolulu, to boost regional economic integration, trade, green growth, job creation in green industries, energy security, and regulatory cooperation.President Hu is expected to speak at the meeting. He will introduce China's stand on the topics and call for "improving global economic governance, shifting the growth methods, promoting economic globalization and regional economic integration," according to Chinese diplomats.Hu will join other APEC leaders in meeting with the APEC Business Advisory Council (ABAC), which presents recommendations to APEC leaders in an annual dialogue and advises APEC officials on business sector priorities and concerns.During this year's dialogue, APEC leaders are expected to discuss regional economic integrity, the development of small- and medium-sized enterprises, food security and other issues with ABAC representatives.This year's APEC meeting convenes at a time when the global economic recovery is fraught with instability and uncertainty, and encounters growing risks and challenges.Some major economies are experiencing an economic slowdown, while in the eurozone, sovereign debt risks are rising in some countries. High inflationary pressure is a problem in emerging economies, including some in the Asia-Pacific region. Protectionism in various forms is mounting.In face of the challenges, the APEC leaders will look for effective measures to stimulate the global economy, regional economic integration, free trade and investment, and economic and technological cooperation.China hopes the APEC members will implement the economic growth strategy agreed on last year, striving to achieve a balanced, inclusive, sustainable, innovative and safe economic growth, said Wu Hailong, assistant foreign minister of China, at a press briefing last week.He said that China expects the APEC members to comprehensively promote regional trade and investment liberalization, adding that all members should fulfill their commitments and oppose all forms of trade protectionism.APEC should strengthen economic and technical cooperation to enhance the ability of the developing members to develop further, and therefore to achieve common prosperity, said the senior diplomat."APEC members generally hold positive attitudes toward U.S. proposals in various fields such as green growth, innovation policy. But some of the U.S.'s expected outcomes are beyond the capacity of the developing members, and they have expressed their difficulties and concerns," Wu said.

  

WELLINGTON, Jan. 2 (Xinhua) -- Chinese lanterns or life from a distant planet?New Zealand meteorologists said Monday they were opting for the former and other mundane explanations after being inundated with reports of UFOs since the start of the New Year.WeatherWatch.co.nz said it normally received "a handful" of eyewitness reports of meteors and lights in the sky, with about 10 reports on a busy day.However, since Sunday, the reports of "floating orbs" and UFOs had been flooding in from around the world at a rate of about 10 each hour.WeatherWatch.co.nz weather analyst Philip Duncan said the reports ranged from "normal meteor sightings to the strange and unusual.""Many people around the world have been outside celebrating the New Year," said Duncan in a statement."In the U.S., where most of the sightings came from, conditions were fairly mild and dry in many areas - so more people were outside to see things. Finally, it's 2012, the year the world is supposed to end according to the Mayans and it seems many are already worrying."One report from Ireland on the weather information company's website said, "At half ten new years eve as My mother and I were heading out of our house to go to town we both saw a strange orange pulsing light. My first guess was it could be a Chinese lantern but it was moving very fast in a perfect straight line. There was no wing and a lantern would sway a little and go up not straight across. The light then began to slow and slightly fade. After a few seconds it got brighter and sped up again until we lost sight of it behind our house. My mother saw the same thing around ten past twelve later that night in the same general area."The statement quoted other reports, including one from Spain: " My father and I saw them in Spain at 00:45 am, but there were 5 or 6 of them all in a vertical line quite close to the earth.""Susana" wrote from an unknown location, "yesterday around 1230 or 1245 there were some red brownish lights first i saw one of them and kind of got my attention and of the sudden there were a BUNCH of them i couldnt count them but i can say there were around 30 lights UFO'S OR CANDLE LIGHTS who knows all i know i saw those lights and were beautiful. Are we ready for the 2012? are we enough educated not to panic?"The WeatherWatch.co.nz statement branded the reports "2012 hysteria.""WeatherWatch.co.nz believes most people witnessed meteors, or shooting stars, Chinese lanterns (which appear as slow moving orange lights) and other normal aircraft such as helicopters and planes," it said.

来源:资阳报

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