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SAN DIEGO (KGTV) -- Looking for somewhere to take the kids this weekend? Look no further than the Annual Fall Back Festival.Themed in the 1880’s, the free festival will be hosted in the Gaslamp Quarter in downtown San Diego on November 5 from 11 a.m. to 4 p.m.Throughout the event, kids can take a pony ride, learn to churn butter, dip their own candles and pan for gold. Booths will be set up at the festival where kids can learn about different nationalities and how they’ve contributed to the makeup of San Diego.There will also be a spaghetti, pie or ice cream eating contests. Yum!Click here for more information on the festival. 648
SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) — If you’re thinking about trading in your used car, now might be the time.Used car prices are beginning to cool off but remain near the historic highs caused by the pandemic, according to data from Edmunds.After a peak in September, dealers paid 3.3% less on average for trade-ins in October. The average used vehicle transaction price, however, remained flat at a record-high ,418 in October because of an influx of relatively new off-lease vehicles."If your household has a second vehicle that you are thinking about selling because it's going unused during the pandemic, there's no point in holding onto it in the hopes of its value increasing again,” said Ivan Drury, Edmunds' senior manager of insights. “You won't get a dramatically higher value for your trade-in than you would have just last month, but you should still get a bit more money than usual since values are still inflated."Used vehicles are worth 16.9% than they did last year, according to the Manheim Used Vehicle Value Index.What caused the historic spikeIn some ways, the pandemic was a time machine for used car prices, reversing depreciation and making pre-owned vehicles worth more than they did a year ago.“That’s kind of crazy to see appreciation on a used vehicle,” Drury said.Drury said he sold a car after owning it for a year for the same price. “That’s unheard of.”Industry experts say it’s a matter of supply and demand. During the pandemic, the supply of used cars dropped, while the demand soared. Both caused prices to spike to record levels.On the supply side, the shutdown of new car manufacturing had a cascading effect on the used car market.“We weren’t churning out new cars, which meant there wasn’t much for shoppers to buy. Therefore people weren’t trading in their used cars,” said Michelle Krebs, Autotrader’s executive analyst. “Everything just kind of stopped.”On top of fewer trade-ins, the pandemic brought the car rental industry to a standstill. Normally, companies like Hertz and Enterprise refresh their fleets, selling off about two million used cars a year. Car rental companies kept their fleets parked during the early months of the pandemic.The third reason supply plummeted: a lot of people decided to put off car buying and extended their leases, so those vehicles weren’t available for sale, although that is now beginning to change.At the same time the supply of used cars dropped, demand for used vehicles surged.“The factories were shut down. They weren’t producing. A lot of consumers, even if they wanted to buy new, they suddenly had to look at used,” Drury said. “That jacked up demand. We had consumers fighting for the same units of inventory.”Demand also rose because people in metro areas that typically relied on public transportation decided to get cars for the first time. And in an environment with a lot of financial uncertainty, used cars were a more affordable option, Krebs said.Low interest rates and stimulus checks also fueled demand by giving consumers more buying power, according to Krebs and Drury.With car rental businesses picking back up and lease extensions beginning to end, the supply of used cars has begun to stabilize. That means now may be the time to sell your used car, particularly before the calendar flips to 2021 and vehicles get one model year older, Drury said.You’ll get more for your used car if you trade it in now, but there’s a trade-off: “You’re also going to pay more for a new car,” Krebs said. 3489
SAN DIEGO (KGTV) — Memorial Day Weekend kicked off Friday night on the USS Midway. As a part of their Legacy Week, they had their annual benefit concert. This year, Daughtry took the stage. Kevin Beam is a big fan and made sure to buy his tickets early, “you got Memorial Day Weekend, Daughtry and beautiful San Diego”. People filled the top deck of the Midway. Ahead of the concert, the USS Midway Foundation presented three ,800 checks to different local charities. The night served as a way for people to remember and honor those who gave the ultimate sacrifice. Penny Erickson was especially grateful for the event Friday, “I’m from a military family my dad was from Pearl Harbor so it means a lot to me.” Chuck Erickson is a volunteer for the USS Midway and a veteran. Friday night, he tells 10News he’s making sure he is grateful all weekend long, “a lot of people lost their lives giving us the freedom we have today”. The USS Midway will have there Legacy Week events through Memorial Day. 1009
SAN DIEGO (KGTV) — Kids, parents, and youth sports leaders held a protest in front of the San Diego County Administration Building on Saturday to voice their concerns over the state’s regulations regarding games and competitions.Currently, under California coronavirus restrictions, youth sports can practice, as long as six feet of social distancing can be maintained, but they can't play games. People who gathered Saturday said the lack of games is taking a toll on the youth.“Thank you for honoring our safety but I think our mental health is important as well and for that to be good and top-notch, we need to be allowed to play our sports and escape from life,” said 7th grader Zoey Hagan, who stood with other girls in her soccer club.Bob Turner is both Executive Director of Presidio Soccer League and President of the Southern California Youth Soccer Association and said the athletes should be able to play games. He said they have created safety plans, including spacing out the times of games and shortening games to avoid crowds, only allowing one parent for each athlete, and also requiring masks of all referees, parents, and substitute players. Turner said they’ve sent countless letters and filled-out petitions to the state, but have not gotten a response. A spokesperson for San Diego County said the county has also been asked about plans for youth sports. They also asked the state and have not heard about what’s next.“This is small potatoes to them compared to a lot of the other things opening but it is our youth and what’s more important than our kids. We’re destroying these kids with what’s happening through the schools and now we’re taking this away. This is the only outlet some of these kids have,” said Turner.At Saturday’s protest, speakers took turns sharing their personal experiences. One parent questioned why other businesses can operate, but these athletes can’t play games.“It is infuriating to me that we’ll open up beaches, we’ll open up Home Depot, we’ll open up restaurants. These people can make their money. We can take care of the adults and make sure they’re doing well, but our kids are sequestered?” he said, addressing the crowd.After a handful of speakers comprised of parents and athletes took to the podium, a group of young athletes held a 'what about us' banner and marched around the admin building while chanting "let us play." 2394
来源:资阳报