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NAIROBI, Aug. 18 (Xinhua) -- The World Health Organization (WHO) on Thursday decried increased number of confirmed cholera cases in the Somalian capital Mogadishu, and growing reports of acute watery diarrhea in Kismayo and other crowded urban centers, saying an urgent multi-sector response to contain the spread of this highly contagious disease is being mounted.The UN health agency said has confirmed cholera in Banadir, Bay, Mudug and Lower Shabelle regions and the number of acute watery diarrhea cases has increased dramatically in the last few months.WHO Representative for Somalia Marthe Everard said combination of poor sanitation conditions, a shortage of safe water, overcrowding and high malnutrition rates, creates the perfect combination for infectious diseases, such as cholera and pneumonia, to spread and increase the number of deaths. "For the last few years, a network of health workers reporting to the early warning system is in place, however they report through a health facility or mobile clinic. Yet the large numbers of displaced people in Mogadishu are making it more difficult to record the various diseases," Everard said in a statement issued in Nairobi. "We urgently need more mobile clinics that will provide basic health care services to the many displaced and who will strengthen the reporting on new outbreaks. This is critical to our response and our ability to save lives."According to WHO, about seventy-five percent of all cases of acute watery diarrhea are children under the age of five.Since January this year, 4,272 cases of acute watery diarrhea/ cholera have been reported in Banadir Hospital in Mogadishu alone. However, at this stage most of the cholera cases in the various regions are contained and under control. "Our major concern is to monitor and detect new disease outbreaks in the many informal settlements set up by internally displaced people in and around Mogadishu", says Everard.Although cholera is endemic in the country, the last major cholera outbreak was in 2007 with an estimated 67,000 cases.WHO said recent efforts to cholrinate the water supply of Mogadishu, along with efforts to improve hygiene and sanitation have prevented a serious outbreak but with the large influx of some 100,000 people alone this year into Mogadishu, bringing the total number of IDPs in the capital to an estimated 470,000, many are living in overcrowded settlements, there is an acute shortage of safe water and adequate sanitation. "There is no need for a child to die of diarrhea, yet this is tragic reality for a Somali child, who is acutely malnourished. It is a lethal combination." said Rozanne Chorlton, UNICEF Representative for Somalia. "These types of diseases can be prevented and treated quickly, but to save children's lives we need to make sure safe water, sanitation and hygiene along with early access to primary health care, are an integral part of our emergency response."WHO said partners in the health and water and sanitation sectors are currently preparing for a potential 100,000 cholera cases including 80,000 moderate cases and 20,000 severe cases.Emergency diarrheal disease kits made up of medical supplies such as syringes, infusions, and oral rehydration fluids (ORS), already prepositioned by UNICEF and WHO have been sent to 13 hospitals.An additional 200 diarrheal disease kits, each able to treat 100 severe cases and 400 moderate cases are being procured and should be in Southern Somalia in the next few weeks, it said.In addition, WHO said, the case management of severe dehydration with and without malnutrition is being strengthened and focus is now on mobilizing a network of already trained community health promoters to move from door to door with health hygiene education messages. "Health posts will be stocked with essential medicines and ORS to identify and promptly treat patients. Many of Southern Somalia' s rural areas and urban centers rely on shallow wells, which unless protected or treated with chlorine can serve as the perfect breeding ground for water borne diseases," it said.To respond to this threat and prevent a major outbreak, the UN health agency said partners in the water, sanitation and hygiene sector are scaling up their actions to target 1.5 million people across high risk areas of the south.Supplies of chlorine and essential items for hygiene and household treatment and storage of water are being distributed.Already 217 water sources are being chlorinated and 58 water point outlets benefitting 483,200 residents and internally displaced people in Mogadishu.In addition, household hygiene supplies, including water purification tablets, soap and buckets, enough for 48,000 families, are being distributed at existing feeding centers for malnourished children.Campaigns to educate families about the treatment of drinking water, safe disposal of waste and encourage hand washing with soap will also be scaled up in high risk communities.As part of the updated 2011 UN Consolidated Appeal for Somalia, an estimated 80 million U.S. dollars is needed for the health sector and 78 million dollars is required for the water, sanitation and hygiene sector.So far, each sector has respectively raised 30 percent and 37 percent of the required money.
WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.
SAN FRANCISCO, July 12 (Xinhua) -- Google+, the social networking service Google unveiled only two weeks ago, is estimated to surpass 10 million users on Tuesday, possibly becoming the fastest growing product in the history of the Internet.According to Ancestry.com founder Paul Allen (not the co- founder of Microsoft), after passing 10 million users, Google+ " could reach 20 million users by this coming weekend if they keep the Invite Button available."Allen looks for last names on Google+ and compares them with U. S. Census Bureau data on the popularity of surnames to statistically project the number of Google+ users."Since I have been tracking this same cohort of surnames from my first day, I am able to accurately measure growth over time," he said in a blog post on Google+ website.Google so far has not released any details about the Google+ users or the number of users. Speaking at a press event last Thursday in Sun Valley in the U.S. state of Idaho, former Google CEO and current Executive Chairman Eric Schmidt said there are " millions" of users.Industry watchers think the estimate may not be completely accurate, but Allen should be capturing the growth trajectory of Google+, which shows that a social network could undergo an exponential growth in its early days.
COPENHAGEN, June 7 (Xinhua) -- The outbreak of infections caused by E. coli bacteria may be over in Denmark as no new cases have been reported here since Friday.According to Denmark's National Serum Institute (NSI), there are 18 confirmed cases of severe intestinal infection caused by exposure to the bacteria as of Monday. No new infections have been reported since Friday, it added.The confirmed cases are said to consist of 10 men and 8 women aged between 23 and 81 years of age. Seven show symptoms of kidney failure which is associated with advanced stages of the infection.All but one are believed to have contracted the infection while traveling in northern Germany, where the outbreak started, the NSI said.So far, the E. coli infection has claimed 21 lives in Germany, which reports over 2,100 confirmed and suspected cases. It has also spread to 12 countries according to the World Health Organization (WHO)."This particular strain of E.coli has been identified in some people sporadically in the past, but it has not been known to have been associated with outbreaks in the past," a WHO spokesperson said Friday, adding it was a "very, very rare strain."Health authorities in Germany now suspect bean sprouts as the source of contamination in this outbreak, although this is yet to be confirmed.Dr Kaare Moelbak, an epidemiologist at NSI told Danish media Sunday that bean sprouts were a "very likely" source of contamination.Cucumbers were initially suspected and Denmark's food authority continues to warn against eating raw tomato, cucumber or lettuce from Germany until the source is established.Children are normally most vulnerable to E. coli infection but most of those infected in this outbreak are above the age of 20 years, Moelbak told Xinhua last week.He said children are likely less affected by this outbreak as they usually eat fewer salads than adults.In Germany, it is mostly women who have been affected by the infection. Moelbak explained the skew in infections saying women tend to choose to eat more vegetables than men, in comments made to Danish media Thursday.
BEIJING, Sept. 6 (Xinhuanet) -- Scientists from Tufts University of the U.S. have created the world's smallest electrical motor in a single molecule.The finding was published in the journal Nature Nanotechnology on Monday.In the research, scientist successfully made a single molecule accept an electrical charge and rotate as fast as 120 revolutions per second."This is the first time that electrically-driven molecular motors have been demonstrated, despite a few theoretical proposals," said Charles H. Sykes, professor of chemistry at Tufts who led the team.The single molecule electric motor could lead to new types of electrical circuitry, giving hope for scientists to apply it in medicine and engineering, he said."The next thing to do is to couple it to other molecules, lining them up next to one another so they're like miniature cog-wheels, and then watch the rotation propagation down the chain," said Sykes.