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SAN DIEGO (KGTV) -- In one San Diego neighborhood alone, around a half dozen residents have reported seeing rattlesnakes dangerously close to their front doors.The Department of Fish and Wildlife says avoid tall grasses and heavy brush if you can. And if your kids are playing in snake country — ditch sandals for a pair of boots.RELATED: Warm temps brings rattlesnake sightings across San Diego 408

SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) — Lunar New Year kicks off in San Diego and thousands prepare to celebrate a civil rights icon.Lunar New Year celebrations at SDCCU Stadium and SeaWorld are running through the weekend in celebration of the Year of the Rat. Locals can check out all the delicious Asian-inspired foods and traditional dancing and performances marking the occasion.This weekend will also celebrate Martin Luther King Jr. as floats, marching bands, and more parade down Harbor Dr. to pay tribute to Dr. King and his work during the civil rights movement. 10News live be live streaming the parade on 10News.com, our 10News mobile app, on Facebook, and on your television streaming device (Roku, Apple TV, Amazon Fire).MORE: Don't see anything you like? Check out our event calendar for even more local eventsOr, visit with the camels, sheep, birds, and more in Ramona, where Oasis Camel Dairy Farm is holding an open house event with tons of activities for families. Borrego Springs also packs a weekend of cinematic fun in the desert with their annual film festival. Here's a look at all the fun this weekend:THURSDAYBorrego Springs Film FestivalWhere: Borrego Springs Performing Arts Center; Cost: - 5(Thursday - Sunday) Enjoy the works of young and seasoned filmmakers at the Borrego Springs Film Festival, filled with opportunities to network with filmmakers, take part in Q&A sessions, listen to panel discussions, and check out a variety of wonderful films.Winter Paradice: Skate, Create and CelebrateWhere: Fleet Science Center; Cost: -(Thursday - Sunday) The holiday spirit is still strong at The Fleet Science Center for a special winter exhibit. Take off your flip flops and get skating on a synthetic ice rink, make your own ornament, or create your own ice cream as a holiday treat at the Skate, Create, Celebrate exhibit. Special pricing and hours also invite guests out for late-night skating and cocktails.FRIDAYSan Diego Lunar New Year FestivalWhere: SDCCU Stadium; Cost: - (Friday - Sunday) SDCCU Stadium hosts the San Diego Lunar New Year Festival, bringing dragon and lion dancing, firecrackers, games, a variety of local food vendors, and more for three days in celebration of Lunar New Year.Shen Yun 2020Where: California Center for the Performing Arts, Escondido; Cost: - 0(Friday - Sunday) The excitement of Shen Yun returns to San Diego, bringing a colorful and theatric display of traditional Chinese culture through five millennia. With stunning costumes, high-tech backdrops, and a unique blend of music and dance, Shen Yun immerses audiences into a multi-dimensional journey of classic Chinese dance. SATURDAYThe Oddities & Curiosities ExpoWhere: Del Mar Fairgrounds; Cost: Free-Explore the world of the strange and unusual at the Del Mar Fairgrounds at the San Diego Offities & Curiosities Expo. Guests can peruse jewelry made from bones, skulls, insects, original artwork, performances featuring human suspension, and more of the strange, weird, and unusual.Oasis Camel Dairy Open Farm eventWhere: Oasis Camel Dairy; Cost: - (Saturday - Sunday) Enjoy a weekend in Ramona visiting camels, sheep, donkeys, and more at Oasis Camel Dairy. The farm's Open Farm event invites the public in for camel rides, pet feeding, a game area, bird and animal shows, and more farm exhibits.Bloom Yoga fundraiserWhere: Bloom Yoga, El Cajon; Cost: VariesBloom Yoga is hosting a donation-based yoga class to help a Jamul 6-year-old boy who was involved in a car accident and is currently hospitalized. The yoga studio is hosting a class in hopes of raising money to help his mom with medical expenses.SeaWorld Lunar New YearWhere: SeaWorld San Diego; Cost: Starting at online(Thursday - Sunday) SeaWorld is hosting a month's worth of Lunar New Year celebrations featuring amazing acrobatics, dancing and cultural performances around the park, as well as interactive activities for families and, of course, some delicious Asian-inspired cuisine for Lunar New Year.SUNDAY40th annual Martin Luther King Jr. Day ParadeWhere: Harbor Drive; Cost: FreeThe 40th annual Martin Luther King Jr. Parade steps off on Jan. 19, bringing floats, high school bands and drill teams, colleges, churches, and many more to Harbor Drive to honor the work of Dr. King. The parade is free and begins at 2 p.m. in front of the County Administration building.San Diego Restaurant WeekWhere: Various locations; Cost: - San Diego Restaurant Week brings special pricing and delicious eats to hungry locals, with more than 180 restaurants taking part in the week-long event offering two-course lunch price points from to , and three-course dinner options from to .Carlsbad Marathon, Half Marathon, and 5KWhere: Marron Rd. and Monroe St.; Cost: - 9San Diego runners take off in the first of three races this year as part of the Triple Crown series with the Carlsbad Full or Half Marathon. Carlsbad's half marathon takes runners on 8 miles along the Pacific Ocean, Buena Vista Lagoon, and on Highway 101. The out-and-back course is described as "gently rolling" with no major elevation changes and mostly unobstructed views of the ocean. 5193

SAN DIEGO (KGTV) - Many of the 134 cats rescued from a Lakeside apartment are up for adoption in County animal shelters. Sheriff’s deputies who were conducting a welfare check at the apartment Thursday discovered the cats and called animal services.Most of the animals appear to be healthy and well-fed, though stand-offish at the moment.  RELATED: 'Dozens' of cats found inside Lakeside apartment during elderly neglect callThe adoptable animals are at the shelters in Bonita and Carlsbad.  All have been checked out by the veterinary staff and given flea and worm medicines.  Each will be spayed or neutered and chipped before adoption.  The adoption fee is per cat or kitten. 745

SAN DIEGO (KGTV) — It's something many of us do in San Diego: We see a picturesque sunset. Rummage around for our phone and open up its camera. Snap a photo and post it to social media.One San Diegan who did just that could see her photo named the Smithsonian's mobile photo of the year.Jacqueline Mckune was walking along the Pacific Beach boardwalk with a group of friends when they stopped to notice the serene orange glow of the evening's sunset."It happened to be a really good sunset too, we just took some previous pictures before with the whole group," McKune said, and that's when she noticed a particular subject against the scenic backdrop.RELATED: Where to capture the most picturesque scenes of San DiegoThe silhouette of man creating massive bubbles with rope strung between two poles against the soft glow of the sunset."So this guy’s making these huge bubbles … and I saw the colors with the sunset behind it," McKune said. Snap.She posted her photo to Facebook and soon, commentators suggested she submit it to a photo contest. After a quick search, she came across the Smithsonian's 16th Annual Photo Contest.RELATED: Convoy Street rooster mural highlights efforts for future neighborhood archwayThat was in June of 2018. McKune's photo would slowly climb with interest: First being a photo of the day, then an "editor's pick.""It was really, really exciting," McKune says. Now, it's a finalist in the mobile category against 9 other finalists picked from thousands of submissions from hunderds of countries. And locals can help make sure it takes home the prize by voting on the Smithsonian's website here."I’m hoping to get at least the photo category," McKune said. "I’m usually a dramatic person so [if I win] there’s probably a scream in there."Voters can submit one vote per day until March 29 at 2 p.m. for McKune's photo. 1855