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SAN DIEGO (KGTV) -- Border Patrol is searching for the people on board a Panga boat that washed ashore near Sunset Cliffs.A neighbor says they heard a dog barking around 3 a.m. Monday morning then saw the boat while on a morning walk.The boat has “Ensenada. B.C.” painted on the bow. Investigators also found eight life jackets and some clothes.RELATED: Navy searches for owner of abandoned boatBorder Patrol agents say they aren’t sure who was on board the vessel at this time. 486
SAN DIEGO (KGTV) - Anyone touched by Alzheimer's knows how painful the disease is. "It's affected my family. It's affected most families. It's such a prevalent disease. As people get older, it becomes quite likely this will become an issue," said Paul Aisen, director of USC's Alzheimer's Therapeutic Research Clinic (ACTC).Aisen's team began their research in San Diego many years ago and teamed up with USC about four years ago. He's spent over 30 years trying to solve Alzheimer's mysteries and is leading the upcoming clinical trial.Aisen says the large-scale study is the culmination of decades of work from scientists worldwide."Our focus lately has been trying to alter the disease, prevent it, or significantly slow its progression. How should we do that? We think attacking amyloid early is the most promising approach," said Aisen. Researchers believe sticky amyloid deposits, which form on the brain later in life, start the Alzheimer's process. Aging, genetics, and lifestyle factors can all contribute to amyloid build-up.The worldwide clinical trial aims to target amyloid. A drug called BAN2401 will be delivered intravenously, designed to bind to the sticky amyloid. The binding neutralizes beta amyloid and helps "tag" it, so the immune system can recognize it and clear it from the brain. A previous phase 2 study showed that BAN2401 removes brain amyloid and possibly slows cognitive decline.They're seeking participants over 50 who are not yet showing symptoms of Alzheimer's but do have elevated amounts of amyloid on their brain. Researchers can determine that through a PET scan or spinal tap. "We think that the most promising approach of all is to take a vigorous attack on amyloid while the brain is still functioning normally. And we can see amyloid in people many years before they develop the symptoms of Alzheimer's."Investigators hope that by treating a patient with BAN2401 very early in the disease, before symptoms occur, it will significantly slow disease progression. "If we're successful, it will have a huge impact on human health," said Aisen. There will be 100 sites worldwide for the study, including major cities like San Diego and Los Angeles. Study participants will receive treatment for four years, given either the drug or a placebo. Results are expected in seven years, Aisen says. If you or a loved one wants to participate, learn more here.Screening will officially begin in May. 2438

SAN DIEGO (KGTV) -- Border Patrol agents arrested a man after finding more than million worth of narcotics inside his car.According to the agency, the incident began around 4 a.m. on October 4 when the 21-year-old man, a US citizen, entered the I-8 checkpoint.As agents questioned the man, a K-9 alerted authorities to the vehicle.After searching the car, agents found 36 wrapped packages under the driver’s side front tire.The brick-shaped packages were later found to contain 84 pounds of cocaine and four pounds of fentanyl pills.“Criminal organizations go to great lengths to conceal and smuggle dangerous narcotics in order to make millions of dollars. This is done without regard to the health and safety of our communities. I am proud of our Border Patrol agents’ vigilant efforts to keep this poison off our streets,” Acting Chief Patrol Agent Patricia McGurk-Daniel said.Since October 1, San Diego Border Patrol Agents have seized 491 pounds of cocaine, 7,169 pounds of methamphetamine, 178 pounds of heroin, and 383 pounds of fentanyl. 1056
SAN DIEGO (KGTV) -- Authorities are investigating a fire that destroyed a car parked on the side of the freeway in Logan Heights early Monday morning.According to the California Highway Patrol, The incident happened at about 3 a.m. on the southbound lanes of Interstate 15 at Oceanview Blvd.When fire crews arrived, the car was fully engulfed. Firefighters were able to put the fire out quickly.When the smoke cleared, deputies found a rag in the gas tank and says it appeared the car had been set on fire intentionally.No injuries were reported.Arson investigators are looking into the cause of the fire. 613
SAN DIEGO (KGTV) – County leaders Wednesday approved a plan that would allow San Diego businesses such as gyms and local places of worship to operate outdoors at county parks.The new initiative gives businesses another option as they look to operate amid the coronavirus pandemic. Last month, the state implemented restrictions that forced many businesses to either close completely or move outdoors.Under the plan, space at any of the county’s 30 parks could be used for service via a free permit.“We need to be creative and provide a lot of flexibility, particularly to churches, places of worship, gyms, and other fitness-oriented businesses,” said County Supervisor Dianne Jacob, who proposed the plan.Jacob said of the process to obtain permits: “I’m asking the county to streamline the process so it’s a very quick turnaround.”She added the process is similar to Poway’s, a city with a similar plan already in place.San Diegan Joel Nevarez visits San Diego’s Waterfront Park off Harbor Drive every morning for his workout because he enjoys it and the park was one of his only options."Getting some sunlight is good for you. I get some fresh air since I work from home, so I like it,” he told ABC 10News.Nevarez’s gym is one of many businesses that shut down amid COVID-19 restrictions. He said if his studio held classes at the park, he'd be one of the first to sign up."It'd be good for anybody and my girlfriend would come, I'd probably tell my friends, too," said Nevarez.Jacob said she hopes the plan will help local businesses get through the pandemic."We're trying to make it as easy as possible for businesses to survive during this difficult time and this is just another way to do it,” she said.RELATED:San Diego City Council approves expanded outdoor operations, 0K relief for small businessesPoway allows fitness classes, religious activities in park space after state closuresVista businesses allowed to take services outdoorsChula Vista highlights businesses moving services outdoors 2013
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