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CLEVELAND — Chadwick Boseman’s death is putting the spotlight on colorectal cancer.Doctors are concerned about the alarming increase in patients between the ages of 25 and 45 years old who are being diagnosed with colorectal cancer.“I’m seeing younger and younger patients. 22-year-olds, 25-year-olds, 26-year-olds, and it’s left all of us a little bit puzzled as to why this is happening,” said Dr. Alok Khorana with the Cleveland Clinic.Carole Motycka went to the doctor for shoulder pain four years ago.“He ordered some tests and it turned out I had a lot more going on than I anticipated,” Motycka said.Motycka was 42 years old when she was diagnosed with colon cancer. She is now on a mission to bring attention, awareness and education to the disease and the increase in younger patients.“Two decades ago, this was widely recognized as a disease in older people,” said Khorana. He said there has been a substantial increase. “Maybe 100% increase, but rates are still very low,” he explained.Colon cancer is much more common among older people. Black men also have higher rates of the disease.There has been a decrease in colon cancer rates among people 50 years old and above, while an increase in the 25-45 age group. Most young patients do not have a family history of the disease.Experts believe catching colon cancer early is the key to survival. But young people are typically diagnosed much later, and Khorana said the cancer seems to be more aggressive.Doctors don’t yet know what is causing the spike in young people.“There are a lot of clues. There’s been an obesity epidemic in the younger population that came 10 to 20 years before the rise in colon cancer,” said Khorana. “A second clue offered is antibiotic use in young people,” he added.Boseman, who played superhero Black Panther on screen, fought a battle off-screen against colon cancer privately for four years.“It’s sad to know it had to happen to have awareness take place but also it’s good to know we can have the conversation on a bigger platform and stage,” said Motycka.Click here for a look at symptoms of colon cancer. This story originally reported by Tracy Carloss on News5Cleveland.com. 2182

CITRUS COUNTY, Fla. — A woman was attacked by an alligator on Wednesday while she was swimming in a lake in Citrus County, according to the Florida Fish and Wildlife Commission.The FWC says 24-year-old Felicitie Marie Gillette was swimming in Lake Hernando around 1 a.m. when an alligator grabbed her by the left arm and began to drag her underwater. She was reportedly able to fight off the alligator and call 911 for help. Gillette was taken to Ocala Regional Hospital for treatment of her injuries. According to the FWC, she was treated and released. She sustained non-life threatening injuries.The alligator is believed to 5 to 6-feet long.The FWC and the Citrus County Sheriff's Office are working to catch the alligator. A trapper has also been called to the scene.The public beach access to Lake Hernando is closed while a wildlife trapper searches for the alligator.  923

Consumers with questions about the recall can contact Kristyn Castellante, Customer Relations Coordinator at 856-532-661. Media with questions can contact media coordinator Alissa Davis at 856-532-6615. 210

Congratulations to the newest United States Senator @SenMarkKelly. I know he’ll serve the people of Arizona well, and I look forward to working together to build this country back better.— Joe Biden (@JoeBiden) December 2, 2020 235

Could the no-calorie sweetener you rely on to replace sugar in your diet actually cause weight gain instead of the weight loss you were expecting?The answer may be yes, according to a new study."Artificial sweeteners are not risk-free," said Brian Hoffmann, assistant professor in the Department of Biomedical Engineering at the Medical College of Wisconsin and Marquette University, and a lead author of the study. "They are a very controversial topic when it comes to health and nutrition ... but they're so prevalent in society that I think we owe it to ourselves to try and figure out what's actually going on."Hoffmann presented his new research Sunday at the annual?Experimental Biology meeting in San Diego. Relying on rats and human cell cultures, his team identified a number of pathways linking artificial sweeteners with metabolic changes at the genetic level that could lead to diabetes and obesity. Specifically, the researchers found that three weeks of exposure to aspartame and acesulfame potassium -- two artificial sweeteners frequently combined in products such as Equal -- altered the expression of certain genes responsible for lipid metabolism in the cells of both rats and humans."Aspartame had some significant changes, and one of those was an increase in lipids in the bloodstream and a decrease in a biomolecule that is involved in clearing (lipids) from the bloodstream. And we saw the exact same thing with the acesulfame potassium," Hoffmann said."We then took those particular sweeteners and put them on endothelial cells -- the cells that line the blood vessels and would be exposed to them in the body -- and we detected a marked dysfunction, suggesting why sweeteners and diet soda have been linked to potential cardiovascular problems," he added.What was perhaps most surprising, according to Hoffmann, was that these metabolic changes did not occur in the presence of natural sugars such as glucose and fructose. This suggests that artificial sweeteners could contribute to metabolic disorders such as diabetes and obesity by an entirely different mechanism than natural sugars, he said.Artificial sweeteners appear to contribute to metabolic disorders by altering the activity of certain genes responsible for the breakdown of macromolecules such as fats and proteins, Hoffmann said. This is different from normal sugars, which contribute to cardiovascular disease through insulin resistance and by damaging the cells lining the body's blood vessels."People are generally consuming non-nutritive sweeteners believing they are a 'healthy choice,' but this may not be true," said research scientist Meghan Azad of the University of Manitoba in Winnipeg, who was not involved in the new study."This is especially important given the widespread and increasing consumption of artificial sweeteners in the general population and the increasing use of artificial sweeteners in our food supply," said Azad, who has authored a paper that reviewed a number of studies on the potential downside of artificial sweeteners on weight and health.According to Azad, over 40% of adult Americans consume no-cal sweeteners on a daily basis, and studies that measure the sweeteners in blood and urine show that many people who report not using artificial sweeteners are unknowingly consuming them.It's the latest assault in the ongoing debate over artificial sweeteners and their impact on health -- a debate that began when one of our most popular foods, sugar, turned sour in terms of health. 3527

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