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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

Johnson & Johnson's stock fell as much as 11 percent on Friday — on track for its worst day since 2002 — after a Reuters report said the company knew for decades that asbestos was in its baby powder.The company has been grappling with lawsuits alleging some of its talcum powder products caused cancer. But the Reuters report cites documents and other evidence that indicate company executives, mine managers, scientists, doctors and lawyers knew about the problem and failed to disclose it to regulators or the public.The plunge in J&J's shares rippled across Wall Street. J&J is among the most widely held stocks and it's also a member of the Dow.Reuters said it examined documents, including depositions and trial testimony, that show that from at least 1971 to the early 2000s, J&J's raw talc and finished baby powders sometimes tested positive for small amounts of asbestos, a human carcinogen that can cause cancer.According to Reuters, the documents also depict successful efforts to influence US regulators' plans to limit asbestos in cosmetic talc products and scientific research on the health effects of talc.J&J has responded, saying "Simply put, the Reuters story is an absurd conspiracy theory, in that it apparently has spanned over 40 years, orchestrated among generations of global regulators, the world's foremost scientists and universities, leading independent labs, and J&J employees themselves."Reuters published an emailed statement from J&J Vice President of Global Media Relations Ernie Knewitz said: "This is all a calculated attempt to distract from the fact that thousands of independent tests prove our talc does not contain asbestos or cause cancer. Any suggestion that Johnson & Johnson knew or hid information about the safety of talc is false."On July 19, 2002, shares of Johnson & Johnson tumbled 16 percent as federal regulators investigated a former employee's allegations of false record-keeping at a plant that made an anemia drug linked to serious side effects.d. 2051

KEYSTONE, Colo. -- A North Carolina man died after hitting a tree while skiing at Keystone Resort in Colorado over the weekend.The Summit County Sheriff's Office said CPR was in progress when deputies responded to the resort shortly before 1 p.m. Sunday.The 32-year-old skier from Raleigh had been on an intermediate trail when he struck the tree, according to the resort. Keystone didn't say which trail the crash occurred on. The victim was transported to Saint Anthony Keystone Medical Clinic, where he was pronounced dead."Keystone Resort, Keystone Ski Patrol and the entire Vail Resorts family extend our deepest sympathy and support to our guest's family and friends," Keystone Resort Vice President and General Manager Geoff Buchheister said in a written statement.The skier has not yet been identified. 833

LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

Kim Jong Un has become the first North Korean leader to step into South Korean territory since 1953, crossing the demarcation line separating the nations for a historic summit on Friday morning.He was greeted by South Korean President Moon Jae-in and the two leaders shook hands, before walking along a red carpet to the Peace House for the first meeting between the leaders of the divided Koreas since 2007.Both men traveled to the demilitarized zone (DMZ) on Friday for a full day of talks on three subjects with worldwide implications -- the denuclearization of the Korean Peninsula, a peace settlement and the improvement of bilateral relations.Crowds of supporters, holding signs calling for denuclearization, had waved off the South Korean President as he left his residence in Seoul and his motorcade's hour-long drive north towards the DMZ was broadcast live to the world.Huge banners have been displayed across the South Korean capital of Seoul proclaiming "Peace, a new start" amid rumors the two leaders could discuss signing an official peace treaty finally ending the Korean War.Kim would "open-heartedly discuss" all the issues with Moon, and was entering talks with the hope of "achieving peace prosperity and reunification of the Korean Peninsula," North Korean state media KCNA said.The summit is the result of months of diplomatic wrangling and negotiating on the part of Moon, a longtime advocate of peace between the Koreas. It will also set the stage for the first meeting between a sitting US president and North Korean leader when Donald Trump and Kim meet in May or June.However, stakes are high and some observers are doubtful the two sides can bridge the gap created by 60 years of antagonism and suspicion.Official talks are scheduled to begin at 10.20 a.m. local time (9.20 p.m. ET Thursday). 1828