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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890

RANCHO PENASQUITOS -- A group of residents in Rancho Pe?asquitos is sounding the alarm about a trio of dense developments that could add 1,500 housing units within 1.5 miles of each other.The group, called PQ-NE Action, notes the northwest part of Rancho Pe?asquitos only has one road in and out. They are raising concerns that the road could not handle the influx in the case of an emergency, such as a wildfire evacuation. "We fully understand things are going to change, but not change to a point where the neighborhood becomes threatened from a safety standpoint," said Junaid Razvi, a 40-year resident and spokesman for the group. RELATED: San Diego's top neighborhoods to get more rental space for the moneyCurrently, Lennar is building the 600-unit Pacific Village complex just east of Carmel Mountain Road. Two more could be on the site of the Hotel Karlan, which shut down Dec. 31. The hotel portion of the property could be rebuilt into as many as 370 homes. The Encinitas-area development company that owns it did not respond to requests for comment. Meanwhile, Lennar is proposing to build more than 530 new housing units on the hotel's old golf course.PQ-NE Action is now calling on Councilman Mark Kersey to step in. "They are moving fast on this, and so we would like to see a pause," Razvi said. RELATED: Making it in San Diego: Changing market could mean opportunity for entry-level San Diego homesIn a statement, Kersey said he understands the concerns and hopes the property owners will work with the community to address them.A spokeswoman for Lennar says the company will do exactly that as part of the approval permitting process. 1661

President Donald Trump, House Speaker Paul Ryan and Senate Majority Leader Mitch McConnell honored the late evangelist Billy Graham while he lies in honor at the US Capitol Wednesday.Graham, an evangelical minister and spiritual confidant to American presidents, died at the age of 99 last week."The man had such a gift with connecting with people," Ryan said in his remarks honoring the late Reverend. "When listening to Reverend Graham, it was like he was right there next to you."He continued: "Here lies America's pastor."  540

President Donald Trump sought to distance himself from the Justice Department official he just named as acting attorney general in the face of mounting criticism about the legality and propriety of his appointment."I don't know Matt Whitaker," Trump said of the new acting attorney general, saying he hired him because he had worked for since-dismissed Attorney General Jeff Sessions. "He was always extremely highly thought of, and he still is. But I didn't know Matt Whitaker. He worked for Attorney General Sessions."The President's comments are at odds with the relationship Trump has forged with Whitaker in recent months, even as his opinion of Sessions continued to sour. Whitaker has been at the White House dozens of times, including in meetings with Trump, and the two have spoken by phone on several occasions, including on the day that Deputy Attorney General Rod Rosenstein was expected to be fired.Whitaker was not hired as Sessions' chief of staff by virtue of any pre-existing relationship with Sessions, but instead because White House officials believed Whitaker's loyalties would lie at the White House and not with the beleaguered attorney general, sources said.  1196

President Donald Trump's campaign said Tuesday it has filed for arbitration, accusing Omarosa Manigault Newman, the former campaign aide and White House official, of breaching a 2016 nondisclosure agreement with the campaign.The move is the first legal action the Trump campaign has taken since Manigault Newman published a tell-all book about her time as a Trump campaign adviser and senior White House official."Donald J. Trump for President, Inc. has filed an arbitration against Omarosa Manigault Newman, with the American Arbitration Association in New York City, for breach of her 2016 confidentiality agreement with the Trump Campaign," a Trump campaign official said in a statement to CNN.Manigault Newman embarked in recent days on a publicity tour to promote her newly released book, "Unhinged," in which she reveals private conversations during her time on the campaign and in the White House. She has also released several audio recordings of conversations she had with Trump and campaign aides.Trump has slammed Manigault Newman as a "low-life" and called her a "dog" amid the allegations she has leveled, including claiming that she heard an audio recording in which Trump says the N-word, a racial epithet. 1229