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AstraZeneca is the latest drugmaker to announce promising Phase 3 trial results from its COVID-19 vaccine candidate.On Monday, AstraZeneca said its two-shot vaccine candidate has been 90% effective thus far along with no safety concerns.“These findings show that we have an effective vaccine that will save many lives," said Professor Andrew Pollard, the chief executive of the study. Excitingly, we’ve found that one of our dosing regimens may be around 90% effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply. Today’s announcement is only possible thanks to the many volunteers in our trial, and the hard working and talented team of researchers based around the world.”The company added in its press release that its vaccine candidate offers two distinct advantages over vaccines made by Pfizer and Moderna — it's cheaper to produce, and does not need to be stored in ultra-cold conditions before use.AstraZeneca added that the company would "immediately" prepare regulatory paperwork to seek Emergency Use Listing status from the World Health Organization.AstraZeneca is just the latest drug company to report encouraging results from its COVID-19 vaccine candidate.Last week, Pfizer said it had submitted Emergency Use Authorization paperwork to the Food & Drug Administration (FDA) after a final analysis of its vaccine candidate proved to be 95% effective in preventing COVID-19. The FDA is expected to approve the drug in the coming weeks.Moderna has also said that early results show its vaccine candidate to be 95% effective, and is on track to have the drug approved for Emergency Use Authorization by the end of the year.AstraZeneca, Pfizer and Moderna are all shattering records for vaccine development. The three vaccines are all on track to be approved for widespread use in uder a year. Typically, it takes several years for a vaccine to go from development to approval.The announcement comes as COVID-19 is spreading around the world at a rate not previously seen since the pandemic began. And while all three companies are pre-producing their vaccines in the hope that it will be approved, health experts warn that they won't be widely available until spring 2021. 2247

ATLANTA (AP) — A federal judge has sentenced a California man to serve 35 years in prison for traveling to Atlanta to have sex with a 9-year-old girl.The U.S. attorney's office in Atlanta said Tuesday that 40-year-old Craig Alan Castaneda of Imperial Beach must also register as a sex offender and serve 10 years supervised release after his prison term.Castaneda was convicted in December.RELATED: Alabama governor signs bill permitting chemical castration for sex offendersAn undercover FBI agent posted an ad on Craigslist in April 2015 posing as a mother seeking a "teacher" for her 9-year-old daughter. Prosecutors say Castaneda responded, describing his prior experience molesting children.Castaneda continued to communicate with the undercover agent for several weeks and made plans to travel to Atlanta. FBI agents arrested Castaneda when he arrived at the Atlanta airport on May 2, 2015. 904

AUSTIN, Texas (AP) — Texas Lt. Gov Dan Patrick says he's offering up to million in defense of President Donald Trump’s unsupported claims of irregularities in the U.S. presidential election. The Republican said Tuesday he would pay out rewards for information that leads to voter fraud arrests and convictions. A former chief Texas ethics regulator suggested that paying reward money, which would come from Patrick’s political campaign, could run afoul of federal campaign finance laws. There's no evidence of widespread fraud in the 2020 election. 559

As we inch toward another national election, it may seem that bridging social, economic and political division is insurmountable. But one artist has spent years bringing people together with a message of reconciliation.Rich Alapack is the founder of “We All Live Here”, a project that aims to build unity through community partnerships and public art installations.For the last five years, he’s been spreading his message of positivity and inclusiveness through interactive murals.He’s brought together students, educators and businesses to spread the message that “we all live here.”“Income equality, gender equality, racial equality, sexual equality, the environment, all fall under the umbrella of these four really simple words,” explained Alapack.When he first began his work, he was surprised at how much the phrase resonated.“I started getting messages from people all over the world encouraging me to keep spreading this message,” he said.He created a program for schools called ACT, which stands for art, community and technology. So far, he’s worked with 110 different schools and shared the message of positive inclusiveness with almost 40,000 kids.“With this division that's happening in our society these days, you can't tell someone that they're wrong and expect them to change their mind,” said Alapack. “So, this phrase ‘we all live here’ as a phrase to respond when they hear something hateful.”Seven thousand colorful magnetic panels outside one school mural he installed will eventually have messages scribbled on the underside by eighth-graders.“Believe in yourself, and you can do it,” read Alapack from one panel.A two-year study released this past summer by Beyond Conflict, tapped brain and behavioral scientists to look at toxic polarization in the U.S. What they found suggests that the divide is more a function of perception than reality.It’s something Alapack believes we can change.“It's indisputable. We do all live here, and so, from there you can find other common grounds and repair maybe some of this divide,” he said.And whether through chalk, paint or magnetic panels, Alapack says he hopes creativity and engagement will inspire others to look beyond differences to find understanding.“Creativity is this unique superpower that humans have, and if you can get someone to do something that they don't think they can, then all of a sudden that opens their horizons to what other things they might be able to do that they don’t think they can do.” 2490

Authorities have intercepted bombs intended for former President Barack Obama and Hillary Clinton, and several other top political figures were targeted in what authorities are investigating as a connected series of incidents.Also, CNN's New York bureau in the Time Warner Center was evacuated after a package containing a bomb, addressed to former CIA Director John Brennan, was discovered, city and local law enforcement officials said.In addition, sources told CNN that a suspicious package intended for California Democratic Rep. Maxine Waters was intercepted at a congressional mail screening facility in Maryland; New York Gov. Andrew Cuomo received what he said was a device at his Manhattan office; and the San Diego Union-Tribune evacuated?its building after "suspicious looking packages" were spotted outside.The developments, which unfolded rapidly and continued steadily into the afternoon, touched off fear and confusion and immediately invited questions about the motives of those responsible. The recipients of the packages are all prominent targets of right-wing criticism and, in many cases, of President Donald Trump himself."This clearly is an act of terror attempting to undermine our free press and leaders of this country through acts of violence," New York Mayor Bill de Blasio said at an afternoon news conference.CNN, citing a law enforcement official, was initially told a suspicious package containing a pipe bomb that was addressed to the White House was intercepted at Joint Base Bolling in Washington, DC. The Secret Service, however, later said it had only intercepted the two packages intended for Obama and Clinton and called reports of a package headed for the White House "incorrect." 1742

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