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WASHINGTON, April 25 (Xinhua) -- Study by scientists at the Rockefeller University shows that anti-inflammatory drugs reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors (SSRIs), taken for depression and obsessive-compulsive disorder and anxiety disorders.This discovery, published online Monday in the Proceedings of the National Academy of Sciences, may explain why so many depressed patients taking SSRIs do not respond to antidepressant treatment and suggests that this lack of effectiveness may be preventable.The study may be especially significant in the case of Alzheimer's disease. Such patients commonly suffer from depression and unless this can be treated successfully, the course of the illness is likely to be more severe. Depression in the elderly is also a risk factor for developing Alzheimer's Disease and researchers have suggested that treating depression in the elderly might reduce the risk of developing the disease.In the recent study, investigators treated mice with antidepressants in the presence or absence of anti-inflammatory drugs. They then examined how the mice behaved in tasks that are sensitive to antidepressant treatment. They found that the mice's behavioral responses to antidepressants were inhibited by anti- inflammatory/analgesic treatments.They then confirmed these effects in a human population. Depressed individuals who reported anti-inflammatory drug use were much less likely to have their symptoms relieved by an antidepressant than depressed patients who reported no anti- inflammatory drug use. The effect was rather dramatic since, in the absence of any anti-inflammatory or analgesic use, 54 percent of patients responded to the antidepressant, whereas success rates dropped to approximately 40 percent for those who reported using anti-inflammatory agents."Many elderly individuals suffering from depression also have arthritic or related diseases and as a consequence are taking both antidepressant and anti-inflammatory medications. Our results suggest that physicians should carefully balance the advantages and disadvantages of continuing anti-inflammatory therapy in patients being treated with antidepressant medications," leader author Paul Greengard said.
LOS ANGELES, April 10 (Xinhua) -- Drinking green tea and practicing Taichi may promote bone health of postmenopausal women and reduce the risk of inflammation, a new study suggests.The study, conducted by researchers at the Laura W. Bush Institute for Women's Health at the Texas Tech University Health Sciences Center, focused on postmenopausal women and investigated the potential for green tea to work synergistically with Taichi in enhancing bone strength of postmenopausal women.Originating as a martial art in China, Taichi is a mind-body exercise that utilizes slow, gentle movements to build strength and flexibility, as well as deep breathing and relaxation, to move qi, or vital energy, throughout the body.The study findings were published Sunday at EurekAlert.org, the website of the American Association for the Advancement of Science (AAAS).Carried out as a double-blind, placebo-controlled, intervention trial (the "holy grail" of scientific studies), this experiment involved 171 postmenopausal women with the average age of 57 who had weak bones but not full-fledged osteoporosis. Subjects were divided into 4 groups -- placebo: starch pill (placebo) and no Taichi; GTP or green tea polyphenols (500 mg/day) and no Taichi; Placebo plus Taichi (starch pill and practising Taichi three times a week); and GTP plus Taichi.The study lasted for 6 months, during which blood and urine samples were collected and muscle strength assessed.The results show that consumption of GTP (at a level equivalent to about four-six cups of steeped green tea daily) and participation in Taichi independently enhanced markers of bone health by three and six months, respectively. A similar effect was found for muscle strength at the 6-month time point. Participants taking Taichi classes also reported significant beneficial effects in quality of life in terms of improving their emotional and mental health.Perhaps most remarkable, however, was the substantial effect that both GTP and Taichi had on biological markers of oxidative stress. Because oxidative stress is a main precursor to inflammation, this finding suggests that green tea and Taichi may help reduce the underlying etiology of not only osteoporosis, but other inflammatory diseases as well.In the study, the researchers developed an animal model (the ovariectomized, middle-aged female rat), with which they could effectively study the effects of green tea consumption on protection against breakdown of the bone's microarchitecture, according to the AAAS.In humans, this can lead to osteoporosis, a condition common to older women. The researchers say what they have learned from the animal models might also be applicable to postmenopausal women.There is a "favorable effect of modest green tea consumption on bone remodeling in this pre-osteoporotic population," said lead researcher Dr. Chwan-Li (Leslie) Shen, an associate professor at the institute.The researchers plan to soon complete a more long-term study utilizing more technically savvy measures of bone density, according to the AAAS.

LOS ANGELES, May 29 (Xinhua) -- Nineteen percent of
BEIJING, March 10 (Xinhuanet) -- Cigarette displays in shops will be banned and tobacco companies may also be forced to make their products in plain wrappers in an attempt to stop people from smoking, announced the UK government Thursday.The prominent displays and attractive packaging of tobacco have long provided shopkeepers with stable income, keeping addicts hooked and quitters tempted.However, the government's move that will begin as early as spring next year will keep cigarettes hidden away and make it just a tad more difficult for smokers to find their fix."Nearly all adult smokers started smoking before they turned 18 and every year, over 300,000 children under 16 try smoking," said Chief Medical Officer Sally Davies."Smoking is undeniably one of the biggest and most stubborn challenges in public health. Over eight million people in England still smoke and it causes more than 80,000 deaths each year," Health Secretary Andrew Lansley said in his statement on the new law.Now, this move has drawn predictable responses from both sides of the tobacco wars, with health groups cheering and retailers grumbling.The British Medical Association said it was "very pleased" with the announcement, citing research which it said showed that a display ban would play "a key role in discouraging children from smoking and also help smokers quit."On the other hand, industry groups and independent retailers complained it would burden them with the cost of refitting their stores and reduce their already narrow profit margins.And according to media interviews, many people kept skeptical about the real impact the move would have, especially on young smokers.
BEIJING, Feb. 10 (Xinhua) -- The Chinese currency, or the yuan, on Thursday rose to a fresh high of 6.5849 against the U.S. dollar, according to the China Foreign Exchange Trading System.The central parity rate of the yuan, or RMB, was 1 basis point higher than the previous record of 6.585 set on Feb. 9, the previous trading day.The central parity rate has risen against the dollar for a three consecutive trading days.China's central bank announced on June 19 last year that it would further reform the yuan exchange rate formation mechanism to improve its flexibility.On China's foreign exchange spot market, the yuan can rise or fall 0.5 percent from the central parity rate each trading day.The central parity rate of the RMB against the U.S. dollar is based on a weighted average of prices before the opening of the market each business day.
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