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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

Dec. 11-23: 9 a.m.-10 p.m.Dec. 24 (Christmas Eve): 8 a.m.-6 p.m.Dec. 25 (Christmas Day): CLOSEDWestfield UTC (4545 La Jolla Village Dr.) 152

The Wauwatosa Police Department announced that a 15-year-old boy has been arrested in connection to the mass shooting at Mayfair Mall.Eight people including one teen were shot by a suspect at Mayfair Mall Friday afternoon. All are expected to survive their injuries, according to police.Police speculate that the shooting was not a random act but came after an altercation.During the preliminary investigation, witness accounts identified the suspect as a white man in his 20s or 30s. That has now been changed.No photos or videos of the suspect have been released. Once informed that the person was underage, police decided not to release images of the suspect.Police did say multiple arrests have been made.The investigation is still ongoing.This is a developing story. This story was originally published by Patricia McKnight of TMJ4.com. 863

It was not a quiet afternoon Monday at Madison Square Park.Brian Kemsley was walking with his girlfriend when he saw and heard a commotion on the Fifth Avenue side of Madison Square Park. He saw a man trying to rip away a stroller.“It's not a matter of stepping in it's a matter of duty, when you see a woman and her child screaming,” he said.He says the man was asked to let go of the stroller but kept reaching for the baby. The mother was also holding another toddler and everyone was screaming.Kemsley pinned him down and waited for police to arrive. It was captured by a witness on social media. Witnesses recorded video and called 911. Rangers arrived after about fifteen minutes and Kemsley says police took the man into custody. He was taken to a hospital and no one was hurt. This article was written by Greg Mocker for WPIX. 859

Hundreds of people had to be rescued from fast-rising flood waters in the Midwest as several areas dealt with historic flooding that washed out roads and bridges.For many, all they have left is what they could grab from their homes before fleeing. Outside Omaha, Nebraska, animal rescue groups worked to save dozens of farm animals in the area, but others had to be left behind. Weather experts say, so far, 38 spots in the Midwest have reported record-high river levels, most of it caused by rain and melting snow. More evacuations could be on the way as floodwaters head downstream.The governors in Nebraska, Iowa and Wisconsin have declared states of emergency, and some areas could see more chances of rain throughout the week. 745