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济南龟头上长水泡是怎么回事
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发布时间: 2025-05-30 22:21:17北京青年报社官方账号
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  济南龟头上长水泡是怎么回事   

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

  济南龟头上长水泡是怎么回事   

BEIJING, Sept. 18 (Xinhua) -- No newly-formed oil belt was detected in the past two days in north China's Bohai Bay from ConocoPhillips' platforms in the Penglai 19-3 oilfield, the State Oceanic Administration (SOA) said.However, new spots of visible oil spills could still be found around platform C, the SOA said in a statement on Sunday.It is estimated that about 4.51 liters of oil leaked into the sea on Saturday, a slight drop from 6.56 liters from Thursday.No oil clean-up work was done on Friday and Saturday due to the strong winds and rough conditions at sea, the statement said.ConocoPhillips China, a subsidiary of U.S. energy giant ConocoPhillips, first reported spills to authorities in June. The oil spills have polluted more than 5,500 square km of sea water in the Bohai Bay since June.The oil spills have spread to beaches in Hebei and Liaoning provinces. The spills have been blamed for losses in the provinces' tourism and aquatic farming industries.The company on Aug. 31 submitted a report to the SOA claiming that it had screened out all potential sources for oil spills and blocked all oil leaks.After days of evaluation, however, the SOA said on Sept. 2 that ConocoPhillips had failed to complete the clean-up.

  济南龟头上长水泡是怎么回事   

coastline in the U.S. State of California sampled by the state water board harbored fish with mercury in such high concentrations that they shouldn't be eaten by young women and children, a newly released survey has found.Fourteen percent of locations had similarly elevated levels of PCBs, according to the survey published by The Los Angeles Times on Sunday.The most elevated concentrations of mercury and PCBs were found in San Francisco Bay and San Diego Bay, said the survey funded by the state water board.The findings, part of a two-year inquiry that is the largest statewide survey of contaminants in sport fish along the California coast, examined more than 2,000 fish from three dozen species gathered in 2009 from waters near Los Angeles, San Francisco and San Diego, the paper said.The survey highlights the health problem of lingering mercury, a poisonous metal that is found in fish globally, and of PCBs, toxic chemicals the United States banned in the 1970s, the report said.Both substances continue to pose a risk to people who eat fish caught along the California coast because they can lead to nervous system damage and developmental problems in children and can cause cancer, liver damage and reproductive harm, the report quoted researchers as saying."Unfortunately, we're not seeing many areas that are totally clean," said Jay Davis, a senior scientist for the San Francisco Estuary Institute and lead author of the study. But a catalog of where and in what fish the substances abound should help anglers make better choices, Davis said. "With good information, people can reduce their exposure significantly."Sharks had some of the highest levels of mercury because of their unusual tendency to accumulate contaminants in their flesh, while chub mackerel had the lowest levels of contamination, according to the survey.The survey results were used in part to help craft new fish consumption guidelines issued earlier this week for anglers in San Francisco Bay, the first update there by state health officials in 17 years. The advisory identifies shiner perch and other surf perches as unsafe to eat in any quantity and warns young women and children not to eat white sturgeon, striped bass and sharks caught in the bay, The Times said.The buildup of metals and other chemicals in fish is such a problem along the Southern California coast that health officials two years ago expanded the number of fish species on the "do not eat" list from one to five because of high levels of PCBs, mercury and the banned pesticide DDT, the report noted.

  

WASHINGTON, Sept. 15 (Xinhua) -- The rates of new lung cancer cases in the United States dropped among men in 35 states and among women in six states between 1999 and 2008, according to a report released Thursday by the Centers for Disease Control and Prevention (CDC).Among women, lung cancer incidence decreased nationwide between 2006 and 2008, after increasing steadily for decades.The decrease in lung cancer cases corresponds closely with smoking patterns across the nation, the report said. In the West, where smoking prevalence is lower among men and women than in other regions, lung cancer incidence is decreasing faster. Studies show declines in lung cancer rates can be seen as soon as five years after smoking rates decline.The report also noted that states that make greater investments in effective tobacco control strategies see larger reductions in smoking; and the longer they invest, the greater the savings in smoking -- related health care costs. Such strategies include higher tobacco prices, hard-hitting media campaigns, 100 percent smoke-free policies, and easily accessible quitting treatments and services for those who want to quit."Although lung cancer among men and women has decreased over the past few years," said CDC Director Thomas Frieden in a statement. "too many people continue to get sick and die from lung cancers, most of which are caused by smoking. The more we invest in proven tobacco control efforts, the fewer people will die from lung cancer."Lung cancer is the most commonly diagnosed cancer, and the leading cause of cancer death in the United States. Cigarette smoking and exposure to secondhand smoke cause most lung cancer deaths in the United States.

  

YANGON, July 10 (Xinhua) -- Myanmar is projecting to build the first-ever liver transplant hospital in line with the international standard, the local weekly Voice reported Sunday.With the technological help of the Changi General Hospital of Singapore, a 40-million-U.S dollar worth private hospital has started building since late last month.The hospital will offer services for the patients living with heart and kidney diseases and for protection from being affected Methicillin-Resistant Staphylococcus Aureus (MRSA), the report said.In Myanmar, liver transplant will cost about 20 million Kyats ( 25,000 U.S. dollars), lesser than other countries, the report added.Myanmar experts carried out successful liver-transplant operation in 2004 for the first time and in 2009 for the second time.

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