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Family Dollar will close 390 stores this year and make big changes to the stores it is keeping open as the discount chain seeks a turnaround.Family Dollar sells a variety of items for under at rural and urban locations. Dollar Tree bought the company in 2015. But Family Dollar has struggled, and Dollar Tree is under heavy pressure from an activist investor to sell or revitalize the ailing line.Dollar Tree, which sells everything for and caters more to mid-income customers with suburban stores, has a plan for Family Dollar: Close stores, re-brand some locations as Dollar Tree, and renovate others with Dollar Tree merchandise sections."We are confident we are taking the appropriate steps to reposition our Family Dollar brand," Dollar Tree CEO Gary Philbin said in a news release Wednesday.This is a developing story. 846

HENNING, Tenn. — An inmate who escaped a Tennessee prison is a person of interest in a prison employee's murder and is currently 141

Hundreds of people living in northern Syria near the Turkish border are fleeing, herding their loved ones and running from an unknown fate as fires blaze behind them.These people are members of an ethnic minority known as the Kurdish people.Living in a region controlled by the Kurdish People's Protection Units (YPG), a defense force mostly made up of Kurds, the frequently targeted group is once again under attack.Wednesday, Turkey launched an 459

GAITHERSBURG, Md. -- Under the fluorescent lights, inside a series of labs, researchers believe they may have cracked the code to create a vaccine for the new coronavirus, which has officially named COVID-19.“It’s rapidly evolving,” said Dr. Gregory Glenn, president of research and development at the Maryland-based company Novavax. “As a company, we are very invested in looking at how to protect people against infectious diseases.”Novavax is one of several pharmaceutical companies around the world, racing to develop a vaccine for the strain of the coronavirus, which recently emerged in Wuhan, China.“We have to puzzle-solve with vaccines,” Dr. Glenn said. “We think about: what do we want to have the immune response to target? Because that should block the infection and stop the illness and that’s the goal here.”He showed a three-dimensional computerized depiction of what the virus looks like.“The coronavirus – corona being ‘crown’ – has spikes,” he said. “Those spikes have a very important function. They let the virus bind to the human cell and then those spikes act as a syringe to inject genetic material into the human cell.”A vaccine would potentially stop that process, thereby protecting a person from the coronavirus.“We have the gene, we have the vaccine, we’re going to move it into animal testing shortly,” Dr. Glenn said. “Our goal is in late spring to be testing in humans.”It normally takes about 18 months to get human trials started on a vaccine. This shorter time frame is nothing new for the company; they developed an Ebola vaccine within 90 days ready for testing – but there’s a catch.It can take years for a vaccine to get approved, but under dire circumstances sometimes they can be used through something called “expanded access” or “compassionate use” – meaning, the vaccine can be used in humans, before it’s fully licensed.“That happened with Ebola – they didn’t have a licensed vaccine, but they were able to use it under ‘compassionate use,’ they developed evidence that it was working,” Dr. Glenn said.As for a fully approved coronavirus vaccine, experts say that would take longer.“A vaccine in a year would be record-setting time, but not in time to probably have much impact for this disease outbreak,” said Dr. Eric Toner with the Johns Hopkins Center for Health Security.However, if the coronavirus sticks around or comes back stronger in a second wave of the disease, Dr. Glenn said they want to be ready.“We know time is of the essence here,” he said.So far, approximately 73,000 people have been infected and more than 1,800 people have died from the most recent strain of the coronavirus. 2653

George Floyd, the Minnesota man who died while in police custody on Monday, causing nationwide unrest over his death and police brutality more generally, will be laid to rest in Houston. Houston Police Chief Art Acevedo told CNN’s Don Lemon on Sunday that he plans on giving Floyd a police escort when Floyd’s body is laid to rest in Houston. The honor is generally bestowed to officers who died in the line of duty. Acevedo said that Floyd was a well-known former Houston resident. Earlier on Sunday, Acevedo gave an impassioned speech about the state of police-community relations. 595