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SAN DIEGO (KGTV) — It's a disease that kills nearly a half million people a year. Mostly children. But painstaking work right here in San Diego is bringing the world ever closer to ending malaria."After you've been doing it for a while you get a little bit tired," said PhD student Madeline Luth, as she works over a microscope, "You're hands get a little bit shaky."She's part of a research team at UC San Diego involved in tedious, precise work."I'm using my syringe here to separate out a single mosquito," she said, "to isolate the thorax which contains all of the malaria parasites." Malaria is a parasite spread by mosquitoes; making the insect the deadliest organism on the planet -second only to humans. Millions of people -primarily in poor parts of the world like Africa- are made sick by the parasite every year. And hundreds of thousands die."What we're trying to do is interrupt the process so the infection never takes hold in your liver.," said Dr. Elizabeth Winzeler, who heads up the research team at the UC San Diego School of Medicine. "So you never develop any symptoms of the disease".Dr. Winzeler says here team has tested more than a half million compounds against the parasite. And is now about to release hundreds of promising mixtures to researchers around the world. "They can take the recipes and the information that we've used and start their own anti-malarial drug development," says Dr. Winzeler.The open door approach with no intellectual property protections, is made possible by billions of dollars in grants from the Bill & Melinda Gates Foundation. It is also a necessity since the vast majority of those new drugs will save, are too poor to pay for medicine. The venture is purely to save lives. "We're doing this for the good of humanity, says Dr. Winzeler, "And I think everyone is on board with this idea." Even if, says PhD student Madeline Luth, some of the work is hard to explain."It's a little strange telling people I dissect mosquitoes every Wednesday morning." 2022

SAN DIEGO (KGTV) -- In an effort to help San Diego's homeless population, the City of San Diego is proposing a third storage facility the homeless can use to store their belongings. The city organized a town hall in July to gather input for the facility that would be placed on 54th and Lea Street.According to the San Diego Housing Commission, the facilities provide a "safe place for individuals who are experiencing homelessness to keep their belongings as they look for work, attend classes, or meet with a service provider or doctor."One of the centers, located on the 200 block of 16th Street, provides bins for more than 400 homeless individuals. Although the centers provide a service to San Diego's homeless population, some residents have made their opposition clear. Before one of the facilities opened in Sherman Heights, residents voiced their concerns. Neighbors told 10News they worried the facility would increase illegal activity and pose safety concerns in the area. To address concerns, security was placed inside the building as well as patrols sent out into the neighborhood. The timeline below shows the recent history of homeless storage centers throughout the city: 1199

SAN DIEGO (KGTV) — Independent reviews by the FDA show the COVID-19 vaccines by Pfizer and Moderna have similar levels of safety and efficacy, although there are early indications of potential differences.Both vaccines rely on the same basic approach: jumpstarting the immune system with messenger RNA. The FDA confirmed their overall efficacy is essentially identical; 95 percent for Pfizer and 94.1 percent for Moderna.However, signals in the data suggest Moderna’s vaccine may better protect against severe cases of COVID-19, while Pfizer’s vaccine may work better in adults over 65. But experts warned those differences may just be statistical illusions.In Moderna’s study of 30,000 volunteers, 30 people got severe cases of COVID-19. All 30 of those cases were in the placebo group, suggesting the vaccine offers powerful protection against the most serious symptoms.In Pfizer’s trial of 44,000 volunteers, one vaccinated person got a severe case compared to 10 people in the placebo group.“We still need more data,” said Dr. Abisola Olulade of Sharp Rees-Stealy. “It's not a reason to recommend one versus the other.”In adults over 65, the efficacy of Moderna’s vaccine dipped slightly to 86.4 percent. Pfizer’s vaccine was 92.9 percent effective in people aged 65 to 74 and 100 percent effective in individuals 75 and up.“When I think people in the community look at that number, they might say, ‘Oh, that Moderna vaccine probably isn't as good for the older population compared to the Pfizer vaccine.’ But as a clinician looking at numbers, they're both amazing,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.FDA scientists found both vaccines are safe but short-term side effects are common, especially with Moderna’s drug. Both vaccines are administered in two doses. The table below lists the percentage of vaccinated volunteers who reported a side effect after either dose, although side effects were most common after the second injection.Side effect Moderna PfizerFatigue 68.5% 62.9%Headache 63.0% 55.1%Muscle pain59.6%38.3%Joint pain44.8%23.6%Chills43.4%31.9%Fever14.8%14.2%Typically the symptoms went away in one day.“Just because a vaccine has side effects doesn’t mean it’s not safe,” said Dr. Olulade. “We know that side effects happen actually because your immune system is working and waking up. It's actually a positive thing.”The slight difference in side effects could be because of differences in the way researchers polled volunteers, or it could be something with the architecture of the vaccines, experts said.The companies use different tiny bubbles of fat to enclose the messenger RNA. Moderna’s bubble is a little stronger and more stable so it doesn’t need to be stored at sub-arctic temperatures.“It could be that [Moderna’s] elicits a little more inflammation than the other,” Dr. Chin-Hong said.Having slightly more side effects could be a sign that Moderna’s vaccine prompts a stronger immune response that might lead to longer-lasting immunity, but the durability of either vaccine remains one of the most pressing unanswered questions.The biggest difference may be where the vaccines are deployed. Since Pfizer's vaccine needs to be stored at such cold temperatures, experts said Moderna's vaccine may be prioritized for rural hospitals and community health centers that lack ultra-cold storage units. 3370

SAN DIEGO (KGTV) — July 4th weekend has arrived in San Diego, guaranteeing plenty of fun around town for the family.On Thursday, there are plenty of celebrations and fireworks displays to check out around the county. See our maps below for a look at where to catch a spectacular display above San Diego.This weekend, San Diego Pride gets going with She Fest, celebrating the talents and contributions of women within and between the LGBT and larger San Diego communities.MORE: Don't see anything you like? Check out our event calendar for even more local eventsThe U.S. women's national soccer team walks into the World Cup final Sunday, and Petco Park is celebrating with a massive watch party at Park at the Park.And San Diego Comic-Con gets an early start with Superheroes' Night Out at the New Children's Museum and the PAWmicon animal adoption event and festival in Balboa Park.Here's a look at this weekend's events:THURSDAYJuly 4 celebrationsWhere: Throughout San Diego County; Cost: VariesAcross San Diego County, several cities will be holding their own Fourth of July celebrations, from fireworks to festivals. For a look at celebrations happening across San Diego, click here. If fireworks are your thing, click here for a look at fireworks displays around the county.The Cado pop-up museum Where: North City; Cost: - (Thursday - Sunday) "The Cado" pop-up museum opens in San Marcos' North City development, bringing interactive art installations like the Ripe Room, Haas Hall, and The Pit Stop to guests who want to dig deeper into the fruit.Summer SafariWhere: San Diego Zoo Safari Park; Cost: Starting at Summer Safari returns to the Safari Park from May 25 to Sept. 1, bringing live music, arts and crafts, pop-up entertainment, up-close animal experiences, and more fun activities for families to enjoy.FRIDAYRooftop Cinema Club: Pretty WomanWhere: Manchester Grand Hyatt; Cost: - Enjoy a movie under the stars as Rooftop Cinema screens Pretty Woman on the Manchester Grand Hyatt's fourth-floor terrace. The outdoor venue hosts bottomless popcorn, cocktails, games, and of course city views under the stars.WonderspacesWhere: B Street Pier; Cost: Free - The popular, unique art show Wonderspaces hits San Diego with immersive, interactive exhibits sure to spark your imagination, including exhibits filled with helium-filled globes and 3,700 thin multicolor nylon cords.Food Truck FridayWhere: Balboa Park; Cost: Free to attendThe end of the week special brings together several food trucks for delicious fare and live entertainment by local performers. Large family game sets are also rolled out at the plaza's "living room" setup. Some of Balboa Park's museum and educational institutions set up booths during the events to offer hands-on activities and crafts for kids. Some museums also offer special late-night hours.SATURDAYSuperheros' Night OutWhere: New Children's Museum; Cost: - It's a superheroes' night out at the New Children’s Museum’s, where kids are invited to come dress up in masks and capes for an after-hours party with dinner, drinks, entertainment, a costume contest, access to the Museum’s art installations, superhero-themed activities and more.She FestWhere: North Park Community Park; Cost: FreeShe Fest is a festival that celebrates and supports the talents and contributions of women while fostering meaningful connections within and between the LGBT and larger San Diego communities. The festival highlights San Diego Pride next weekend.Horizon Music FestivalWhere: Embarcadero Marina Park North; Cost: - Big Boi of Outkast headlines Horizon Music Festival with Elephante and others, showcasing a blend of relaxation and good beats, dancing, delicious food and drink, and more. SUNDAYWorld Cup watch partyWhere: Petco Park; Cost: FreeThe Park at the Park is hosting the final match in the Women's World Cup featuring the U.S. women's team as they look to hold on to their title. Gates open to the public at 7:30 a.m. and will remain open for the match. Select concessions will also be open in the park to purchase. A live DJ will be on hand for music, along with appearances by the Pad Squad, photo opportunities, giveaway items and interactive activities. Tanabata FestivalWhere: Japanese Friendship Garden; Cost: - Celebrate Tanabata, the meeting of the stars Orihime and Hikoboshi in the Milky Way galaxy on the seventh day of the seventh month, in Balboa Park with festival foods, carnival games, cultural performances, demonstrations, and more at Japanese Friendship Garden.PAWmiconWhere: Comic-Con Museum, Balboa Park; Cost: Helen Woodward Animal Center will host their annual PAWmicon, a free dog- and kid-friendly event to get families into the Comic-Con spirit and celebrate their canine companions. A costume contest will be held for both dogs and owners, and the event will also feature music, games, comic-themed prizes, and dog goodies. 4946

SAN DIEGO (KGTV) - Many of the 134 cats rescued from a Lakeside apartment are up for adoption in County animal shelters. Sheriff’s deputies who were conducting a welfare check at the apartment Thursday discovered the cats and called animal services.Most of the animals appear to be healthy and well-fed, though stand-offish at the moment.  RELATED: 'Dozens' of cats found inside Lakeside apartment during elderly neglect callThe adoptable animals are at the shelters in Bonita and Carlsbad.  All have been checked out by the veterinary staff and given flea and worm medicines.  Each will be spayed or neutered and chipped before adoption.  The adoption fee is per cat or kitten. 745