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SAN DIEGO (KGTV) - Conservationists planted dozens of Short-leaved Liveforever in a secret location Friday in an effort to help the succulent survive, according to San Diego Zoo Global Plant Division and the Chaparral Conservancy.The reason for the secrecy was due to the same two reasons the plant is endangered: Illegal harvesting and vandalism. David Hogan, Director of Chaparral Conservancy, lent seeds from an area in Torrey Pines to San Diego Zoo Global, which cultivated the plants for two years.Hogan grew up in San Diego and says his earliest memories are toddling around in nature. He says he's been keeping a close eye on these tiny plants for years, and is now thankful for the handful of grants from various agencies to make reintroducing Liveforever possible.The plant gets its name from its life cycle, sprouting leaves in the summer, and dying down to its root in the winter.Just off the trail, two yellow measuring tapes sat straight as arrows, creating a grid for the Zoo Global team to note where they planted root shafts. "[They're] pretty tiny; the only way we're going to find them is from these measurements," Joyce Maschinski, Vice President of Science and Conservation with Zoo Global said.She wasn't kidding. Looking down, the tiny plant blends right into the rocks surrounding it. Only a trained eye and careful steps keep these conservationists from stepping on the precious wildlife.Hogan said the Liveforever would grow about three times its size in a good year. In the summer, they can bloom beautiful flowers. That's part of the draw for illegal harvesters who sell the plants in Asia.Conservationists used tweezers to hold the roots in just the right place as they filled the marker-sized hole and watered the plants."Everybody knows that it's kinda hard to kill a succulent so they should be able to do well as long as we get them in there, in the right place to grow, and give them some water," Research Assistant with Zoo Global, Joe Davitt, said.Altogether they planted 46 root shafts across two locations."They're nowhere near as appealing to a lot of people as a, say, a baby polar bear or a giraffe, but they're just as equally important. They're part of the incredible biodiversity of life on earth," Hogan said.The Liveforever only grows in five places on Earth, between La Jolla, Carmel Valley and Del Mar, Hogan said."Sometimes it's appealing to go out onto the cliffs to get a better shot for the camera or the ocean or the sunset, but that's unfortunately where a lot of these really rare and endangered animals and plants live," Hogan said, encouraging people to stay on the trails."A lot of us who work with conservation connect with nature as home; this is where we go for comfort, this is where we feel the most connected with the rest of the world," he said. 2817
SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

SAN DIEGO (KGTV) -- Authorities confirmed Monday that a deadly shooting in Chula Vista and a second shooting at Sunset Cliffs in April are related.Police say three people, Britney Canal known as "Giggles", 29, Cesar Alvarado, known as "Capone", 39, and Michael Pedraza, known as "Monster", 27, have been charged and are being held without bail for the deadly crime spree.According to a prosecutor, the murder charges with special circumstances may lead to the death penalty. To illustrate the callous nature of the suspects, the District Attorney said the three celebrated after killing a man in Chula Vista. 627
SAN DIEGO (KGTV) — As President Trump and Democratic lawmakers battle over funding for the president's border wall project, construction at the border is already slated to begin early this year.Texas-based construction company SLSCO was awarded 7 million last month for a series of wall projects along the U.S.-Mexico border in California beginning in February. The contracts include up to 14 miles of secondary wall and 15 miles of primary pedestrian replacement wall in the San Diego, Yuma, and El Centro sectors.A Border Patrol spokesperson said construction of a primary pedestrian wall was already approved, though could not comment as to whether secondary wall construction was previously approved or tied directly to President Trump's Executive Order for a continuous border wall.RELATED: Roughly 150 migrants attempt to climb border fence, throw rocks at Border Patrol agentsIn February 2019, construction on 14 miles of secondary wall will start adjacent to San Diego's primary fence replacement project that is currently underway. That primary fence construction began in June about one-half mile from the Pacific Ocean, extending east to the base of Otay Mountain. SLSCO is also in charge of that project.Then in July 2019, construction on 15 miles of pedestrian replacement wall will start, with 11 miles in Calexico, three miles in Tecate, and one mile in Andrade. The Border Patrol spokesperson was unable to say exactly where construction would take place in these areas.10News reached out to SLSCO for comment on their upcoming wall projects and will update with their comments. 1606
SAN DIEGO (KGTV) -- Authorities are searching for a woman who disappeared while driving from San Diego to Victorville nearly two weeks ago. According to the San Bernardino Sheriff’s Department, 53-year-old Izetta Burney went missing on November 24. Burney disappeared while driving home to Victorville after visiting a San Diego spa, a friend tells 10News. According to the friend, Burney’s phone goes straight to voicemail and her credit cards and bank account show no signs of activity. Burney was last seen in Victorville driving a black 2008 four-door BMW with California license plate number 7EXG207. She is described as five feet, 11 inches tall with a tattoo on her right arm and a mole above her lip. She was last seen wearing a black top and black spandex pants. Anyone with information is asked to call the San Bernardino Sheriff’s Department at 760-552-6800 or 911. 885
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