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With over 160 vaccines in development, the race to defeat COVID-19 continues.A California company hopes to deliver its vaccine to your mailbox; one that is pain-free and doesn't require a needle and syringe."One of the things I wanted to do was make vaccines more patient-friendly, so they don't hurt and you're not afraid to take them," said Dr. Dan Henderson, a virologist and the CEO of Verndari, Inc.The biopharmaceutical company is based in Napa, California. Dr. Henderson originally came to the wine country to retire but stepped back into the lab during the Ebola crisis. He says some adults avoid vaccines because of a fear of needles, so Verndari set out to do something different. They created the VaxiPatch, a single-dose vaccination kit that uses a dermal patch with a metal microneedle array to deliver vaccines. Once applied, the person wears the patch like a Band-Aid for five minutes. The vaccine uses the COVID-19 "spike" protein that enables the virus to infect human cells and works to enhance a person's immune person.Unlike traditional vaccines, the patch doesn't need to be refrigerated, which Henderson says would make it easier and cheaper to send to developing countries. The company initially set out to make a flu vaccine but switched gears during the pandemic; they continue to adapt to the world's changing needs. "Now, for the First World, it's a shelter-in-place vaccine," said Henderson.They're working with the FDA to see if it could be mailed to your home. The vaccine would leave a temporary blue mark so the patient could take a photo and send it to their health care provider as proof of vaccination. In collaboration with the UC Davis, they've begun clinical trials in animals. Dr. Henderson says so far the results are promising.Other researchers are also working on getting a patch like this on people's arms.Scientists at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center have created a fingertip-sized skin patch that is also showing promising results in animal testing. Verndari hopes to test its vaccine in humans in the fall, and if all goes well, it could be made available to the public early next year. Dr. Henderson believes they could manufacture about 20 million doses a month. "It would mean a lot because it's important to me to make a contribution and a contribution like that, to me, is priceless." 2408

in the Senate.The bill, which was introduced by the Trump administration, was blocked after Democratic Senators voted against it.Democrats have said the bill offers too much to corporations and not enough protection against the funds being used for stock buybacks and executive pay. Republicans urge that the bill be passed quickly, so the federal government begin sending Americans checks of up to ,200 to help stimulate the economy.As the Senate bill failed, House Speaker Nancy Pelosi introduced her own stimulus bill in the House of Representatives — a move that could lengthen the amount of time it could take for the government to provide aid to economically strapped Americans. 688

YOSEMITE NATIONAL PARK, Calif. (AP) — A man died after falling into a river at Yosemite National Park on Christmas Day, the National Park Service said Friday.The man apparently slipped down Silver Apron, a large, sloping granite area above Nevada Fall, and suffered a head injury, government spokesman Andrew Munoz said in a statement. The ongoing investigation is taking longer than usual because of the partial government shutdown, he said.Munoz said rangers responding to a 911 call arrived on scene in less than an hour and pulled the man, who has not been identified, from the water."Medical attention was provided to the visitor, but he died from his injuries," Munoz said.The man's death was first reported by Outside Magazine, which noted that at least 10 people died in the park last year, including another man who slipped and fell to his death near Nevada Fall.No further details on the Dec. 25 fatality were released.Munoz said the park didn't issue a press release about the death because of the shutdown, which began two weeks ago and forced furloughs of hundreds of thousands of federal government employees.Yosemite remains open to visitors during the shutdown, and crowds of visitors have been driving into the park to take advantage of free admission. This week, the park announced new access limitations and several closed areas within the park because of problems with human waste, damage to resources and other public safety concerns during the shutdown.Under the park service's shutdown plan, law enforcement staff remains on duty.Munoz said the visitor was not in a closed area when he fell. 1622

With down payments less than 10%, you’ll pay mortgage insurance for the life of the loan. With a loan-to-value equal to or greater than 90%, you’ll pay the premiums for 11 years. 181

With temperatures soaring into triple digits before noon, parking in downtown Palm Springs, California, usually comes at a premium.For the past few months, however, parking is actually pretty easy to find.City leaders stopped enforcing parking violations in mid-March and El Patron restaurant manager Miguel Espinola is hoping to cash in.“The extra money (customers) were going to spend on the parking lot, and I think they can spend it on an extra margarita or a cup of coffee,” he said. Parking citations generate money for the city’s general fund.“Obviously parking is important for a tourism destination like Palm Springs,” said Palm Springs city manager David Ready.He says the Palm Springs has lost about ,000 since early April.While the loss isn’t terrible, Ready says the cost is an indicator of a much bigger problem.“Because of our tourist economy, we’ve taken a hit of almost million to million that we’ve had to cut out of our budget,” he said.Other cities across the country are losing a lot more money by not handing out parking tickets during the pandemic.In Denver, city leaders say parking citation revenue is down nearly million compared to this time last year. Additionally, parking meter revenue was down almost million in the same time frame.In Miami Beach, those numbers are even higher -- with a combined loss of more than million.“When cities see their budgets being cut it means they cannot provide as many goods,” said Alex Padilla, a professor of economics at MSU Denver. He says moving forward, cities may have to find other ways to replace that revenue.“They might charge higher prices for public transportation,” Padilla said. “They might not provide things like fireworks.”Back in Palm Springs, Ready says the city had to cut parking enforcement positions to offset the cost of not issuing parking citations.“The reason parking has always been an issue to us is because it keeps the orderly flow of you know for our downtown economy,” he said.As Palm Springs faces another round of shutdowns, Ready says the city might not enforce parking citations until next year.“The last thing we want to do is give a tourist, someone who is coming to visit, us a parking ticket,” he said 2235